Elamipretide (SS-31) studies: 372 papers with results
Page 3 of 8
- Mitochondria-Related Ferroptosis Drives Cognitive Deficits in Neonatal Mice Following Sevoflurane Administration.
Zhang P · Frontiers in medicine · 2022
Animal study (in vivo) · mouse · 1 result
- Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization.
Zhang H · Journal of neuroinflammation · 2023
Animal study (in vivo) · mouse · 4 results
- Mitochondrial oxidative stress induces leaky ryanodine receptor during mechanical ventilation.
Dridi H · Free radical biology & medicine · 2020
Animal study (in vivo) · mouse · 6 results
- Mitochondria-Targeted Peptide SS31 Attenuates Renal Tubulointerstitial Injury via Inhibiting Mitochondrial Fission in Diabetic Mice.
Yang SK · Oxidative medicine and cellular longevity · 2019
Animal study (in vivo) · mouse · 19 results
- Administration of antioxidant peptide SS-31 attenuates transverse aortic constriction-induced pulmonary arterial hypertension in mice.
Lu HI · Acta pharmacologica Sinica · 2016
Animal study (in vivo) · mouse · 20 results
- Elamipretide Attenuates Pyroptosis and Perioperative Neurocognitive Disorders in Aged Mice.
Zuo Y · Frontiers in cellular neuroscience · 2020
Animal study (in vivo) · mouse · 3 results
- SS-31 peptide enables mitochondrial targeting drug delivery: a promising therapeutic alteration to prevent hair cell damage from aminoglycosides.
Kuang X · Drug delivery · 2017
Animal study (in vivo) · zebrafish · 6 results
- Elamipretide (SS-31) Ameliorates Isoflurane-Induced Long-Term Impairments of Mitochondrial Morphogenesis and Cognition in Developing Rats.
Wu J · Frontiers in cellular neuroscience · 2017
Animal study (in vivo) · rat · 3 results
- Novel mitochondria-targeted antioxidant peptide ameliorates burn-induced apoptosis and endoplasmic reticulum stress in the skeletal muscle of mice.
Lee HY · Shock (Augusta, Ga.) · 2011
Animal study (in vivo) · mouse · 6 results
- Protective effects of mitochondrion-targeted peptide SS-31 against hind limb ischemia-reperfusion injury.
Cai J · Journal of physiology and biochemistry · 2018
Animal study (in vivo) · mouse · 11 results
- Mitochondria-targeted antioxidant peptide SS-31 mediates neuroprotection in a rat experimental glaucoma model.
Wu X · Acta biochimica et biophysica Sinica · 2019
Animal study (in vivo) · rat · 11 results
- SS31 Ameliorates Podocyte Injury via Inhibiting OMA1-Mediated Hydrolysis of OPA1 in Diabetic Kidney Disease.
Yang Q · Frontiers in pharmacology · 2021
Animal study (in vivo) · 2 results
- Mitochondria-Targeted Small Peptide, SS31 Ameliorates Diabetes Induced Mitochondrial Dynamics in Male TallyHO/JngJ Mice.
Bhatti JS · Molecular neurobiology · 2021
Animal study (in vivo) · mouse · 2 results
- Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia.
Ryan TE · Journal of molecular and cellular cardiology · 2016
Animal study (in vivo) · mouse · 6 results
- Mitochondria-targeted antioxidant peptide SS31 protects the retinas of diabetic rats.
Huang J · Current molecular medicine · 2013
Animal study (in vivo) · rat · 14 results
- Pharmacological targeting of mitochondrial function and reactive oxygen species production prevents colon 26 cancer-induced cardiorespiratory muscle weakness.
Smuder AJ · Oncotarget · 2020
Animal study (in vivo) · mouse · 6 results
- The Mitochondria-targeted Peptide, Bendavia, Attenuated Ischemia/Reperfusion-induced Stroke Damage.
Imai T · Neuroscience · 2020
Animal study (in vivo) · mouse · 7 results
- Metabolic derangement in polycystic kidney disease mouse models is ameliorated by mitochondrial-targeted antioxidants.
Daneshgar N · Communications biology · 2021
Animal study (in vivo) · mouse · 1 result
- Peptide Szeto‑Schiller 31 ameliorates doxorubicin‑induced cardiotoxicity by inhibiting the activation of the p38 MAPK signaling pathway.
Zhang L · International journal of molecular medicine · 2021
Animal study (in vivo) · mouse · 8 results
- SS-31 inhibits mtDNA-cGAS-STING signaling to improve POCD by activating mitophagy in aged mice.
Ji Y · Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
Animal study (in vivo) · mouse · 6 results
- Elamipretide (SS-31) treatment attenuates age-associated post-translational modifications of heart proteins.
Whitson JA · GeroScience · 2021
Animal study (in vivo) · mouse · 3 results
- A mitochondrial-targeted peptide ameliorated podocyte apoptosis through a HOCl-alb-enhanced and mitochondria-dependent signalling pathway in diabetic rats and in vitro.
Wang X · Journal of enzyme inhibition and medicinal chemistry · 2019
Animal study (in vivo) · rat · 9 results
- Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet.
Zhang M · PloS one · 2017
Animal study (in vivo) · mouse · 11 results
- Beneficial effects of SS-31 peptide on cardiac mitochondrial dysfunction in tafazzin knockdown mice.
Russo S · Scientific reports · 2022
Animal study (in vivo) · mouse · 3 results
- Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.
Yang DQ · Oxidative medicine and cellular longevity · 2021
Animal study (in vivo) · mouse · 23 results
- Mitochondria Targeted Peptide Attenuates Mitochondrial Dysfunction, Controls Inflammation and Protects Against Spinal Cord Injury-Induced Lung Injury.
Zhu LL · Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2017
Animal study (in vivo) · mouse · 9 results
- Mitochondria-targeted antioxidant promotes recovery of skeletal muscle mitochondrial function after burn trauma assessed by in vivo 31P nuclear magnetic resonance and electron paramagnetic resonance spectroscopy.
Righi V · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2013
Animal study (in vivo) · mouse · 3 results
- Brown adipose tissue and its modulation by a mitochondria-targeted peptide in rat burn injury-induced hypermetabolism.
Yo K · American journal of physiology. Endocrinology and metabolism · 2013
Animal study (in vivo) · rat · 2 results
- Elamipretide(SS-31) Attenuates Idiopathic Pulmonary Fibrosis by Inhibiting the Nrf2-Dependent NLRP3 Inflammasome in Macrophages.
Nie Y · Antioxidants (Basel, Switzerland) · 2023
Animal study (in vivo) · mouse · 14 results
- Contradictory effects of mitochondria- and non-mitochondria-targeted antioxidants on hepatocarcinogenesis by altering DNA repair in mice.
Wang B · Hepatology (Baltimore, Md.) · 2018
Animal study (in vivo) · mouse · 6 results
- Protective Effects of Antioxidant Peptide SS-31 Against Multiple Organ Dysfunctions During Endotoxemia.
Li G · Inflammation · 2016
Animal study (in vivo) · 12 results
- SS-31 treatment ameliorates cardiac mitochondrial morphology and defective mitophagy in a murine model of Barth syndrome.
Russo S · Scientific reports · 2024
Animal study (in vivo) · mouse · 2 results
- A Water-Soluble Quercetin Conjugate with Triple Targeting Exerts Neuron-Protective Effect on Cerebral Ischemia by Mitophagy Activation.
Cen J · Advanced healthcare materials · 2022
Animal study (in vivo) · 4 results
- Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice.
Bhatti JS · Mitochondrion · 2021
Animal study (in vivo) · mouse · 2 results
- Hypertension Exacerbates Cerebrovascular Oxidative Stress Induced by Mild Traumatic Brain Injury: Protective Effects of the Mitochondria-Targeted Antioxidative Peptide SS-31.
Czigler A · Journal of neurotrauma · 2019
Animal study (in vivo) · rat · 3 results
- SS31, a Small Molecule Antioxidant Peptide, Attenuates β-Amyloid Elevation, Mitochondrial/Synaptic Deterioration and Cognitive Deficit in SAMP8 Mice.
Jia YL · Current Alzheimer research · 2016
Animal study (in vivo) · mouse · 6 results
- Reduced adenosine diphosphate sensitivity in skeletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not denervation.
Pharaoh G · JCSM rapid communications · 2021
Animal study (in vivo) · mouse · 4 results
- SS31 attenuates oxidative stress and neuronal apoptosis in early brain injury following subarachnoid hemorrhage possibly by the mitochondrial pathway.
Shen R · Neuroscience letters · 2020
Animal study (in vivo) · rat · 9 results
- The Mitochondria-Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age.
Mitchell W · Aging cell · 2025
Animal study (in vivo) · mouse (c57bl and 6j) · 9 results
- SS-31 as a Mitochondrial Protectant in the Treatment of Tendinopathy: Evaluation in a Murine Supraspinatus Tendinopathy Model.
Zhang X · The Journal of bone and joint surgery. American volume · 2022
Animal study (in vivo) · mouse · 6 results
- Elamipretide (SS-31) Improves Functional Connectivity in Hippocampus and Other Related Regions Following Prolonged Neuroinflammation Induced by Lipopolysaccharide in Aged Rats.
Liu Y · Frontiers in aging neuroscience · 2021
Animal study (in vivo) · rat · 4 results
- SS-31 Improves Cognitive Function in Sepsis-Associated Encephalopathy by Inhibiting the Drp1-NLRP3 Inflammasome Activation.
Zhong L · Neuromolecular medicine · 2023
Animal study (in vivo) · mouse · 11 results
- Novel Role for Cardiolipin as a Target of Therapy to Mitigate Myocardial Injury Caused by Venoarterial Extracorporeal Membrane Oxygenation.
Swain L · Circulation · 2024
Animal study (in vivo) · pig · 5 results
- SS31 Alleviates Pressure Overload-Induced Heart Failure Caused by Sirt3-Mediated Mitochondrial Fusion.
Suo M · Frontiers in cardiovascular medicine · 2022
Animal study (in vivo) · mouse · 7 results
- SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop.
Shan Z · The journal of headache and pain · 2023
Animal study (in vivo) · mouse · 3 results
- Elamipretide reduces pyroptosis and improves functional recovery after spinal cord injury.
Jiang W · CNS neuroscience & therapeutics · 2023
Animal study (in vivo) · 7 results
- Evaluation of the antioxidant peptide SS31 for treatment of burn-induced insulin resistance.
Carter EA · International journal of molecular medicine · 2011
Animal study (in vivo) · mouse · 3 results
- Mitochondria-targeting peptide SS-31 attenuates ferroptosis via inhibition of the p38 MAPK signaling pathway in the hippocampus of epileptic rats.
Liu X · Brain research · 2024
Animal study (in vivo) · rat (wistar) · 7 results
- SS31, a mitochondrially targeted antioxidant, prevents sepsis-induced reductions in diaphragm strength and endurance.
Supinski GS · Journal of applied physiology (Bethesda, Md. : 1985) · 2020
Animal study (in vivo) · mouse · 9 results
- Post-sepsis chronic muscle weakness can be prevented by pharmacological protection of mitochondria.
Kingren MS · Molecular medicine (Cambridge, Mass.) · 2024
Animal study (in vivo) · mouse · 1 result