Thymosin alpha-1 studies: 615 papers with results
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- Dialyzable leukocyte extracts contain thymosin.
Wilson GB · Thymus · 1984
In vitro (cells) · 3 results
- Modulation of human natural killer cell cytotoxic activity, lymphokine production, and interleukin 2 receptor expression by thymic hormones.
Serrate SA · Journal of immunology (Baltimore, Md. : 1950) · 1987
In vitro (cells) · 1 result
- Thymosin-alpha1 regulates MHC class I expression in FRTL-5 cells at transcriptional level.
Giuliani C · European journal of immunology · 2000
In vitro (cells) · mouse · 5 results
- Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis.
Wei YT · Cancer research · 2022
In vitro (cells) · 8 results
- Thymosin α1 and cancer: action on immune effector and tumor target cells.
Garaci E · Annals of the New York Academy of Sciences · 2012
In vitro (cells) · 1 result
- Thymosin alpha 1 modulates the expression of high affinity interleukin-2 receptors on normal human lymphocytes.
Leichtling KD · International journal of immunopharmacology · 1990
In vitro (cells) · 6 results
- Modulation of interleukin 2 receptor expression on normal human lymphocytes by thymic hormones.
Sztein MB · Proceedings of the National Academy of Sciences of the United States of America · 1986
In vitro (cells) · 1 result
- Thymosin alpha 1 suppresses proliferation and induces apoptosis in breast cancer cells through PTEN-mediated inhibition of PI3K/Akt/mTOR signaling pathway.
Guo Y · Apoptosis : an international journal on programmed cell death · 2015
In vitro (cells) · 6 results
- Characterization of the immunoregulatory properties of thymosin alpha 1 on interleukin-2 production and interleukin-2 receptor expression in normal human lymphocytes.
Sztein MB · International journal of immunopharmacology · 1989
In vitro (cells) · 7 results
- In vitro effect of thymosin-alpha1 and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with chronic hepatitis C.
Andreone P · Journal of viral hepatitis · 2001
In vitro (cells) · 6 results
- Immunoregulatory effects of fraction 5 thymus peptides. I. Thymosin alpha 1 enhances while thymosin beta 4 suppresses the human autologous and allogeneic mixed lymphocyte reaction.
Baxevanis CN · Immunopharmacology · 1987
In vitro (cells) · 7 results
- Thymosin-alpha1 modulates dendritic cell differentiation and functional maturation from human peripheral blood CD14+ monocytes.
Yao Q · Immunology letters · 2007
In vitro (cells) · 9 results
- Aspirin and thymosin increase interleukin-2 and interferon-gamma production by human peripheral blood lymphocytes.
Hsia J · Immunopharmacology · 1989
In vitro (cells) · 1 result
- Differential expression analysis of miRNA in peripheral blood mononuclear cells of patients with non-segmental vitiligo.
Wang Y · The Journal of dermatology · 2015
In vitro (cells) · 1 result
- Solid-phase synthesis of thymosin alpha 1 using tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin.
Wong TW · Biochemistry · 1980
In vitro (cells) · 3 results
- Thymosin α1 activates complement receptor-mediated phagocytosis in human monocyte-derived macrophages.
Serafino A · Journal of innate immunity · 2014
In vitro (cells) · 8 results
- Antioxidant and angiotensin-converting enzyme (ACE) inhibitory activity of thymosin alpha-1 (Thα1) peptide.
Kharazmi-Khorassani J · Bioorganic chemistry · 2019
In vitro (cells) · 10 results
- Thymosin increases production of T-cell growth factor by normal human peripheral blood lymphocytes.
Zatz MM · Proceedings of the National Academy of Sciences of the United States of America · 1984
In vitro (cells) · 3 results
- Thymosin alpha1 is a time and dose-dependent antagonist of dexamethasone-induced apoptosis of murine thymocytes in vitro.
Baumann CA · International journal of immunopharmacology · 2000
In vitro (cells) · mouse · 5 results
- Thymosin alpha1 suppresses proliferation and induces apoptosis in human leukemia cell lines.
Fan YZ · Peptides · 2006
In vitro (cells) · 9 results
- Dual effect of Thymosin α 1 on human monocyte-derived dendritic cell in vitro stimulated with viral and bacterial toll-like receptor agonists.
Giacomini E · Expert opinion on biological therapy · 2015
In vitro (cells) · 5 results
- Involvement of mitogen-activated protein kinases in the signal transduction pathway of bone marrow-derived macrophage activation in response to in vitro treatment with thymosin alpha 1.
Sodhi A · International immunopharmacology · 2002
In vitro (cells) · mouse · 7 results
- Proliferative and anti-proliferative effects of thymosin alpha1 on cells are associated with manipulation of cellular ROS levels.
Qin Y · Chemico-biological interactions · 2009
In vitro (cells) · mouse · 9 results
- Effects of thymic polypeptides on the thymopoiesis of mouse embryonic stem cells.
Peng Y · Cell biology international · 2008
In vitro (cells) · mouse · 4 results
- Signaling pathways leading to the activation of IKK and MAPK by thymosin alpha1.
Peng X · Annals of the New York Academy of Sciences · 2007
In vitro (cells) · mouse · 9 results
- Production of human B and T cell growth factors is enhanced by thymic hormones.
Kouttab NM · Immunopharmacology · 1988
In vitro (cells) · 4 results
- Transcription profile of human lymphocytes following in vitro treatment with thymosin alpha-1.
Matteucci C · Annals of the New York Academy of Sciences · 2010
In vitro (cells) · 1 result
- Thymosin peptides and lymphokines do not directly stimulate adrenal corticosteroid production in vitro.
Vahouny GV · Journal of immunology (Baltimore, Md. : 1950) · 1983
In vitro (cells) · rat · 3 results
- Thymosin α 1 potentiates the release by CD8(+) cells of soluble factors able to inhibit HIV-1 and human T lymphotropic virus 1 infection in vitro.
Matteucci C · Expert opinion on biological therapy · 2015
In vitro (cells) · 3 results
- The octapeptide corresponding to the region of the highest homology between alpha-interferon and thymosin-alpha 1 effectively competes with both cytokines for common high-affinity receptors on murine thymocytes.
Zav'yalov VP · FEBS letters · 1991
In vitro (cells) · mouse · 1 result
- Interleukin 2 receptor expression in patients with head and neck squamous carcinoma. Effects of thymosin alpha 1 in vitro.
Wolf GT · Archives of otolaryngology--head & neck surgery · 1989
In vitro (cells) · 2 results
- Combination of Gemcitabine and Thymosin alpha 1 exhibit a better anti-tumor effect on nasal natural killer/T-cell lymphoma.
Chen M · International immunopharmacology · 2021
In vitro (cells) · 13 results
- Potential Role of Thymosin-alpha1 Adjuvant Therapy for Glioblastoma.
Sungarian A · Journal of oncology · 2009
In vitro (cells) · rat · 10 results
- The modulation of thymosin alpha 1 in the maturation, differentiation and function of murine bone marrow-derived dendritic cells in the absence or presence of tumor necrosis factor-alpha.
Huang Y · International immunopharmacology · 2004
In vitro (cells) · mouse · 8 results
- Thymosin alpha-1 modulates excitatory synaptic transmission in cultured hippocampal neurons in rats.
Yang S · Neuroscience letters · 2003
In vitro (cells) · rat · 4 results
- Thymosin alpha-1; a natural peptide inhibits cellular proliferation, cell migration, the level of reactive oxygen species and promotes the activity of antioxidant enzymes in human lung epithelial adenocarcinoma cell line (A549).
Kharazmi-Khorassani J · Environmental toxicology · 2019
In vitro (cells) · 7 results
- Thymosin-alpha 1, but not interferon-alpha, specifically inhibits anchorage-independent growth of hepatitis B viral transfected HepG2 cells.
Moshier JA · Journal of hepatology · 1996
In vitro (cells) · 4 results
- Receptors for thymosin alpha 1 on mouse thymocytes.
Rinaldi Garaci C · Cellular immunology · 1985
In vitro (cells) · mouse · 2 results
- Thymosin fraction 5 inhibits the proliferation of the rat neuroendocrine MMQ pituitary adenoma and C6 glioma cell lines in vitro.
Spangelo BL · Endocrinology · 1998
In vitro (cells) · rat · 6 results
- Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity.
Armirotti A · Scientific reports · 2019
In vitro (cells) · 4 results
- Interaction of thymic peptide thymosin alpha 1 with VIP receptors in rat intestinal epithelial cells: comparison with PHI and secretin.
Calvo JR · General pharmacology · 1989
In vitro (cells) · rat · 4 results
- Corticosterone-releasing activity of immune mediators.
Torres-Alemán I · Life sciences · 1987
In vitro (cells) · rat · 2 results
- The use of alpha 1 thymosin as an immunomodulator of the response against SARS-Cov2.
Espinar-Buitrago MS · Immunity & ageing : I & A · 2023
In vitro (cells) · 9 results
- Cytokine-mediated apoptosis and inhibition of virus production and anchorage independent growth of viral transfected hepatoblastoma cells.
Yared G · Cytokine · 1998
In vitro (cells) · 4 results
- Thymosin α1 alleviates pulpitis by inhibiting ferroptosis of dental pulp cells.
Wu J · International journal of oral science · 2025
In vitro (cells) · 10 results
- Novel evidence of Thymosin α1 immunomodulatory properties in SARS-CoV-2 infection: Effect on innate inflammatory response in a peripheral blood mononuclear cell-based in vitro model.
Ricci D · International immunopharmacology · 2023
In vitro (cells) · 5 results
- Thymosin-α1 binds with ACE and downregulates the expression of ACE2 in human respiratory epithelia.
Zhang YH · Frontiers in bioscience (Landmark edition) · 2022
In vitro (cells) · 5 results
- A novel thymosin peptide stimulates interleukin-6 release from rat C6 glioma cells in vitro.
Tijerina M · Neuroimmunomodulation · 1997
In vitro (cells) · rat · 2 results
- Phytohemagglutin-stimulated human T cell: prothymosin alpha as an accessory signal.
Cordero OJ · Journal of biological regulators and homeostatic agents · 1990
In vitro (cells) · 2 results
- Immune modulation via dendritic cells by the effect of Thymosin-alpha-1 on immune synapse in HCMV infection.
Espinar-Buitrago MS · International immunopharmacology · 2023
In vitro (cells) · 7 results