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Study · In vitro (cells) · 1984

3 results

Dialyzable leukocyte extracts contain thymosin.

Wilson GB, Paddock GV, Floyd E, Newell RT, Dopson MH

Thymus1 Jan 1984

PMID6464097 (opens in a new tab)PepBankPUB-06464097
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In lymphocytes from two patients with immunodeficiency disease, thymosin alpha‑1 peptide markedly increased the number of E-rosetting cells in vitro.

    In plain wordsIn lab tests of cells from two donors with immunodeficiency, thymosin alpha‑1 raised the number of mature T-cells that form rosettes.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseNumber of E-rosetting cells in immunodeficiency patients
    Study

    humann = 2

    lymphocytes from two patients with immunodeficiency disease
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin alpha 1-peptide purified from thymosin Fraction V and putative thymosin alpha 1 preparations purified from human DLEs were each active not only in increasing the rate of regeneration of T-lymphocyte E-receptors removed by trypsinization but also were active in vitro in markedly increasing t…
  2. 02LabIn vitro (cells)Activity measurement

    In trypsinized human T-lymphocytes, thymosin alpha‑1 peptide purified from thymosin Fraction V increased the rate of regeneration of E-receptors.

    In plain wordsIn lab tests of human T-cells, purified thymosin alpha‑1 sped up the return of surface receptors lost after trypsin treatment.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseRate of regeneration of T-lymphocyte E-receptors
    Study

    humann: not reported in source

    trypsinized human T-lymphocytes
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin alpha 1-peptide purified from thymosin Fraction V and putative thymosin alpha 1 preparations purified from human DLEs were each active not only in increasing the rate of regeneration of T-lymphocyte E-receptors removed by trypsinization

Studies that did not test the peptide alone1

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 03LabNot a test of Thymosin alpha-1 aloneIn vitro (cells)Mechanism

    Human dialyzable leukocyte extracts contained thymosin alpha‑1, which accounted at least in part for their enhancing effect on E-receptor regeneration.

    In plain wordsIn lab tests, white blood cell extracts contained thymosin alpha‑1, which explained part of their effect on T-cell receptors.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableThymosin alpha 1 content of dialyzable leukocyte extracts
    Study

    humann: not reported in source

    trypsinized human T-lymphocytes
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Both physical-chemical and immunochemical results reported herein indicate that the enhancing effect of human DLE preparations on the rate of regeneration of T-lymphocyte E-receptors is due at least in part to the presence of thymosin alpha 1-peptide in these preparations.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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