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Study · In vitro (cells) · 1980

3 results

Solid-phase synthesis of thymosin alpha 1 using tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin.

Wong TW, Merrifield RB

Biochemistry1 Jul 1980Cited by 28 (Europe PMC)

PMID7190831 (opens in a new tab)DOI10.1021/bi00555a021 (opens in a new tab)PepBankPUB-07190831
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    Synthetic thymosin alpha‑1 and its desacetyl analogue had biological activity in the azathioprine-sensitive rosette assay.

    In plain wordsIn lab tests, the synthetic peptides were biologically active in the rosette assay.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableBiological activity in the azathioprine-sensitive rosette assay
    Study

    n: not reported in source

    Synthetic peptides
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    They also had biological activity in the azathioprine-sensitive rosette assay.

Studies that did not test the peptide alone2

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 02LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    Solid-phase synthesis of thymosin alpha‑1 on aminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin gave an improved yield.

    In plain wordsIn lab synthesis, the new resin gave an improved yield of thymosin alpha‑1.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseYield of solid-phase synthesis with the new resin
    Study

    n: not reported in source

    Synthetic peptides
    Outcome group
    Peptide structure and chemistry · Pharmacology

    Source sentences

    Summary
    Use of aminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin resulted in an improved yield and allowed the synthetic products to be purified by simple ion-exchange and gel filtration chromatography.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  2. 03LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    The purified synthetic thymosin alpha‑1 and desacetyl analogue were homogeneous by paper electrophoresis, isoelectric focusing and thin-layer chromatography.

    In plain wordsIn lab tests, the purified synthetic peptides were found to be pure by three separation methods.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableHomogeneity of purified synthetic peptides
    Study

    n: not reported in source

    Synthetic peptides
    Outcome group
    Peptide structure and chemistry · Pharmacology

    Source sentences

    Summary
    The purified synthetic peptides were found to be homogeneous by paper electrophoresis, isoelectric focusing in polyacrylamide gel, and thin-layer chromatography.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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