In lymphocytes from head and neck cancer patients and normal subjects, thymosin alpha‑1 further decreased the levels of IL-2 receptor-positive CD4 and CD8 cells at 48 and 72 hours.
In plain wordsIn lab tests of human lymphocytes, thymosin alpha‑1 lowered the number of cells with IL-2 receptors at 48 and 72 hours.
- Peptide
- Thymosin alpha-1
- Outcome
- DecreaseConcanavalin A-stimulated IL-2 receptor-positive cells at 48 and 72 h
- Study
humann: not reported in source
Lymphocytes from patients with head and neck cancer and from normal subjects- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated
Source sentences
Thymosin alpha 1 further decreased levels of IL-2 receptor-positive (both CD4 and CD8) cells at 48 and at 72 hours.
1 context sentence(design, population, supporting numbers)
Recent evidence for the potential importance of in lymphokine interleukin 2 (IL-2) in patients with cancer prompted a study of the kinetics of IL-2 receptor expression on lymphocytes from patients with untreated advanced head and neck cancer and normal subjects and an evaluation of the in vitro effe…