In human peripheral blood mononuclear cells treated in vitro with thymosin alpha‑1, the transcription profile showed modulation of many genes, including genes not described before.
In plain wordsIn cells, thymosin alpha‑1 changed the activity of many genes in human white blood cells, including genes not linked to it before.
- Peptide
- Thymosin alpha-1
- Outcome
- MixedGene expression in PBMC (transcription profile)
- Study
humann: not reported in source
Human peripheral blood mononuclear cells- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated
Source sentences
our analysis revealed a remarkable number of genes not yet described before to be modulated by this thymic peptide
1 context sentence(design, population, supporting numbers)
To get information on the mechanism of action of Talpha1 and to find new potential applications, we performed the analysis of the transcription profile of 8300 genes in human peripheral blood mononuclear cells in vitro treated with Talpha1.