Skip to content

Study · In vitro (cells) · 1990

2 results

Phytohemagglutin-stimulated human T cell: prothymosin alpha as an accessory signal.

Cordero OJ, Sarandeses CS, Nogueira M

Journal of biological regulators and homeostatic agents1 Jan 1990Cited by 6 (Europe PMC)

PMID2399834 (opens in a new tab)PepBankPUB-02399834
Publisher pageAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In PHA-stimulated human mononuclear cells, the effects of thymosin alpha‑1 depended on the degree of cell stimulation, dose and preincubation time.

    In plain wordsIn lab tests on human white blood cells, the effects of thymosin alpha‑1 changed with cell stimulation, dose and preincubation time.

    Peptide
    Thymosin alpha-1
    Outcome
    MixedEffect on PHA-stimulated PBMC proliferation by stimulation degree, dose and preincubation time
    Study

    humann: not reported in source

    PHA-stimulated PBMC
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The observed effects of Pro alpha and thymosin alpha 1 (alpha 1) on PBMC were found to depend on the degree of cell stimulation, dose, and preincubation-time.
    1 context sentence
    Summary · context
    In this work, we studied the effect of Prothymosin alpha (Pro alpha) on PHA-stimulated PBMC and PBLC.
  2. 02LabIn vitro (cells)Activity measurement

    In PHA-stimulated human PBMC and PBLC, thymosin beta‑4 had no effect at any degree of stimulation and served as a control peptide.

    In plain wordsIn human immune cells in the lab, thymosin beta‑4 had no effect, so it works as a control peptide.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeEffect on PHA-stimulated PBMC and PBLC
    Study

    humann: not reported in source

    PHA-stimulated PBMC and PBLC
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin beta 4 (beta 4) had no effect on either cell type, regardless of the degree of stimulation, which shows that beta 4 may be used as a control peptide to work in this area.
    1 context sentence
    Summary · context
    In this work, we studied the effect of Prothymosin alpha (Pro alpha) on PHA-stimulated PBMC and PBLC.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 4Current

    12 Oct 2026, 18:17 UTC

    Study data updated · source update from Europe PMC

  2. Version 3

    10 Oct 2026, 08:55 UTC

    Study results updated

  3. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  4. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.