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Study · In vitro (cell-free) · 1988

2 results

Classification of the insulin-like growth factor binding proteins into three distinct categories according to their binding specificities.

Forbes B, Szabo L, Baxter RC, Ballard FJ, Wallace JC

Biochemical and biophysical research communications1 Nov 1988Cited by 49 (Europe PMC)

PMID2973786 (opens in a new tab)DOI10.1016/s0006-291x(88)80032-9 (opens in a new tab)PepBankPUB-02973786
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cell-free)Activity measurement

    In binding assays, the acid-stable large serum binding protein subunit bound des-(1-3)-IGF-1 only slightly less than IGF-1.

    In plain wordsIn lab tests, the large serum binding protein subunit bound des-(1-3)-IGF-1 slightly less than IGF-1.

    Peptide
    IGF-1 DES (des(1-3)IGF-I)
    Outcome
    DecreaseLarge serum binding protein subunit binding
    Study

    n: not reported in source

    IGF-binding protein competition assays
    Comparator
    IGF-1
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In addition to the acid stable subunit of the large serum binding protein which exhibits des-(1-3)-IGF-1 binding only slightly less than IGF-1, the small IGF binding proteins can be separated into two classes based on differences in des-(1-3)-IGF-1 and IGF-2 binding potencies.

Studies that did not test the peptide alone1

In this study, IGF-1 DES (des(1-3)IGF-I) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking IGF-1 DES (des(1-3)IGF-I).

  1. 02LabNot a test of IGF-1 DES (des(1-3)IGF-I) aloneIn vitro (cell-free)Activity measurement

    In binding assays, small IGF-binding proteins separated into two classes according to des-(1-3)-IGF-1 and IGF-2 binding potencies.

    In plain wordsIn lab tests, small IGF-binding proteins formed two classes based on their binding of des-(1-3)-IGF-1 and IGF-2.

    Peptide
    IGF-1 DES (des(1-3)IGF-I)
    Outcome
    Not applicableSmall binding protein classification
    Study

    n: not reported in source

    IGF-binding protein competition assays
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    In addition to the acid stable subunit of the large serum binding protein which exhibits des-(1-3)-IGF-1 binding only slightly less than IGF-1, the small IGF binding proteins can be separated into two classes based on differences in des-(1-3)-IGF-1 and IGF-2 binding potencies.

    In this study, IGF-1 DES (des(1-3)IGF-I) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking IGF-1 DES (des(1-3)IGF-I).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:52 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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