In M12 cells exposed to des(1‑3)IGF-I, IGFBP-4 transfectants and controls did not differ significantly in soft agar colony formation.
In plain wordsIn cells exposed to des(1‑3)IGF-I, IGFBP-4 transfectants and controls did not differ significantly in colony formation.
- Peptide
- IGF-1 DES (des(1-3)IGF-I)
- Outcome
- No significant changeColony formation with des IGF-I
- Study
n: not reported in source
M12 prostate epithelial cells transfected with IGFBP-4- Comparator
- Control M12 cells
- Outcome group
- Tumor growth · Cancer
Source sentences
however, in the presence of des(1-3)IGF-I, there was no significant difference between the control and IGFBP-4 transfectants in colony formation in soft agar.
1 context sentence(design, population, supporting numbers)
We have overexpressed the IGF-inhibitory IGFBP-4 in the malignant M12 prostate epithelial cell line to determine the effects on tumor formation and apoptosis.
In this study, IGF-1 DES (des(1-3)IGF-I) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking IGF-1 DES (des(1-3)IGF-I).