| 25 μg once daily | Human | human | oral | 3 months | Randomized trial in people · n = 261 | Sand 2013 |
| 0.3 μg/kg | Human | human | subcutaneous | Not reported | Randomized trial in people · n = 162 | Manno 2011 |
| 50 μg | Human | human | oral | 3 months | Randomized trial in people | Weiss 2013 |
| 75 μg | Human | human | oral | 3 months | Randomized trial in people | Weiss 2013 |
| 300 micro g | Human | human | nasal spray | 2 months | Randomized trial in people | Kadir 2002 |
| 25 μg | Human | human | oral | 28 days | Randomized trial in people | Yamaguchi 2013 |
| 50 μg | Human | human | oral | 28 days | Randomized trial in people | Yamaguchi 2013 |
| 100 μg | Human | human | oral | 28 days | Randomized trial in people | Yamaguchi 2013 |
| 0.2 mg | Human | human | oral | 2 weeks | Randomized trial in people | Hashim 2009 |
| 50 μg | Human | human | oral | 12 weeks | Randomized trial in people | Yamaguchi 2020 |
| 25 μg | Human | human | oral | 12 weeks | Randomized trial in people | Yamaguchi 2020 |
| 120 mcg/day, then 60 mcg/day for 15 days and 60 mcg every second evening for 15 days | Human | human | sublingual | 3 months before withdrawal | Randomized trial in people | Ferrara 2014 |
| 25 µg once daily | Human | human | oral | 3 months | Randomized trial in people | Rovner 2018 |
| 10, 25, 50, or 100 µg | Human | human | oral | 4 weeks | Randomized trial in people · n = 757 | Weiss 2012 |
| 50 and 75 μg | Human | human | oral | 3 months | Randomized trial in people · n = 385 | Weiss 2013 |
| 0.2-0.4 mg daily | Human | human | oral | 6 months | Randomized trial in people · n = 251 | Evans 2011 |
| 120/240 microg MELT; 0.2/0.4 mg tablets | Human | human | sublingual MELT; oral tablet | 3 weeks per formulation | Randomized trial in people · n = 221 | Lottmann 2007 |
| melt 120/240 μg or tablet 0.2/0.4 mg | Human | human | oral | 3 weeks per period | Randomized trial in people · n = 221 | Juul 2013 |
| 120 µg | Human | human | oral melt | 2 weeks | Randomized trial in people · n = 206 | Montaldo 2012 |
| 0.2-0.6 mg | Human | human | oral | 2 weeks | Randomized trial in people · n = 193 | Schulman 2001 |
| 0.1, 0.2 or 0.4 mg | Human | human | oral | 3 weeks | Randomized trial in people · n = 151 | Mattiasson 2002 |
| 0.3 microgram per kilogram | Human | human | intravenous | Not reported | Randomized trial in people · n = 150 | Hackmann 1989 |
| 0.1 mg, 0.2 mg, or 0.4 mg | Human | human | oral | 3 weeks | Randomized trial in people · n = 144 | Lose 2003 |
| 0.1, 0.2, or 0.4 mg | Human | human | oral | 3 weeks | Randomized trial in people · n = 127 | van 2007 |
| 10-100 μg | Human | human | oral | single dose | Randomized trial in people · n = 116 | Yamaguchi 2013 |
| 0.3 micrograms/kg | Human | human | Not reported | Not reported | Randomized trial in people · n = 100 | Rocha 1988 |
| 0.3 micro g/kg | Human | human | Not reported | Not reported | Randomized trial in people · n = 100 | Pleym 2004 |
| 0.3 microgram/kg | Human | human | Not reported | Not reported | Randomized trial in people · n = 95 | Reynolds 1993 |
| 40 microg for 3 weeks then 20 microg for 3 weeks | Human | human | intranasal | 6 weeks | Randomized trial in people · n = 93 | Leebeek-Groenewegen 2001 |
| 0.03 microgram per kilogram | Human | human | intravenous | Not reported | Randomized trial in people · n = 92 | Karnezis 1994 |
| 0.3 micrograms/kg | Human | human | intravenous | Not reported | Randomized trial in people · n = 92 | de 1992 |
| 20 micrograms | Human | human | Not reported | Not reported | Randomized trial in people · n = 91 | Clagett 1995 |
| 30, 60, 120, 240, 360 or 480 microg | Human | human | oral lyophilisate | Not reported | Randomized trial in people · n = 84 | Vande 2006 |
| 0.3 microgram/kg | Human | human | infusion | Not reported | Randomized trial in people · n = 79 | Schött 1995 |
| 400 mug | Human | human | oral | 12 weeks | Randomized trial in people · n = 73 | Fai-Ngo 2005 |
| 0.3 micrograms/kg | Human | human | Not reported | Not reported | Randomized trial in people · n = 65 | Gratz 1992 |
| 0.3 microgram/kg | Human | human | intravenous | Not reported | Randomized trial in people · n = 60 | Seear 1989 |
| 0.3 micro g x kg(-1) | Human | human | intravenous | 20 min | Randomized trial in people · n = 59 | Wong 2003 |
| Two doses of 0.3 micrograms/kg | Human | human | intravenous | Not reported | Randomized trial in people · n = 56 | Rocha 1994 |
| 20 μg | Human | human | intravenous | single dose | Randomized trial in people · n = 54 | Desborough 2023 |