Thymosin beta-4 (human) studies: 835 papers with results
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- Effect of thymosin beta 4 in the presence of up-regulation of the insulin-like growth factor-1 signaling pathway on high-glucose-exposed vascular endothelial cells.
Kim S · Molecular and cellular endocrinology · 2015
In vitro (cells) · 2 results
- Bacterial expression, purification and angiogenesis-promoting activity of human thymosin β4.
Kozaczuk A · Protein expression and purification · 2013
In vitro (cells) · 6 results
- Thymosin β4 is associated with bone sialoprotein expression via ERK and Smad3 signaling pathways in MDPC-23 odontoblastic cells.
Choi BD · International journal of molecular medicine · 2018
In vitro (cells) · mouse · 10 results
- The Effect of Thymosin β4 for Osteoblast Adhesion on Titanium Surface.
Choi BD · Journal of nanoscience and nanotechnology · 2015
In vitro (cells) · 16 results
- [Regenerative medicine of skeletal muscle].
Hara T · Rinsho shinkeigaku = Clinical neurology · 2005
In vitro (cells) · 4 results
- Thymosin β4 stabilizes hypoxia induced brain microvascular endothelial cell dysfunction through S1PR1 dependent mechanisms.
Stewart WG · Scientific reports · 2025
In vitro (cells) · 2 results
- In Vitro Study of Thymosin Beta 4 Promoting Transplanted Fat Survival by Regulating Adipose-Derived Stem Cells.
Li W · Aesthetic plastic surgery · 2024
In vitro (cells) · 6 results
- Thymosin β4 stabilizes hypoxia-inducible factor-1α protein in an oxygen-independent manner.
Ock MS · Annals of the New York Academy of Sciences · 2012
In vitro (cells) · 3 results
- The antiproliferative activity of the tetrapeptide Acetyl-N-SerAspLysPro, an inhibitor of haematopoietic stem cell proliferation, is not mediated by a thymosin beta 4-like effect on actin assembly.
Cheviron N · Cell proliferation · 1996
In vitro (cells) · mouse · 1 result
- Comparison of the effects of thymosin and other thymic factors on modulation of interleukin-2 production.
Zatz MM · Journal of biological response modifiers · 1985
In vitro (cells) · 2 results
- Cell starvation increases uptake of extracellular Thymosin β4 and its complexes with calcium.
Piludu M · International immunopharmacology · 2023
In vitro (cells) · 4 results
- Thymosin β4 promotes glucose-impaired endothelial progenitor cell function via Akt/endothelial nitric oxide synthesis signaling pathway.
Qiu F · Experimental and therapeutic medicine · 2018
In vitro (cells) · 3 results
- [Thymosin β4 inhibits pyroptosis in BV2 microglial cells: a mechanistic study in vitro].
Li YX · Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
In vitro (cells) · 12 results
- Effect of thymosin β4 on lipopolysaccharide‑stimulated brain microvascular endothelial cell remodeling: A possible role in blood‑brain barrier injury.
Stewart W · Experimental and therapeutic medicine · 2023
In vitro (cells) · 2 results
- [Effect and mechanism of thymosin beta 4 on spinal cord-derived neural stem /progenitor cell injury induced by oxidative stress].
Li HW · Zhongguo gu shang = China journal of orthopaedics and traumatology · 2022
In vitro (cells) · rat · 14 results
- [Protective effect of thymosin β4 against oxidative damage in cultured rabbit corneal epithelial cells].
Li X · [Zhonghua yan ke za zhi] Chinese journal of ophthalmology · 2013
In vitro (cells) · rabbit · 5 results
- Effect of two thymosin fraction 5 polypeptides on human peripheral blood lymphocytes.
Kokkinopoulos D · Immunopharmacology and immunotoxicology · 1987
In vitro (cells) · 6 results
- Understanding the effects of ciprofloxacin on corneal epithelial cells: a study using electric cell-substrate impedance sensing (ECIS) technology.
Banga L · Experimental eye research · 2026
In vitro (cells) · 3 results
- Thymosin Beta 4 Protects Hippocampal Neuronal Cells against PrP (106-126) via Neurotrophic Factor Signaling.
Kim S · Molecules (Basel, Switzerland) · 2023
In vitro (cells) · 4 results
- Thymosin beta 3 and beta 4
GOLDSTEIN ALLAN L · 1981
In vitro (cells) · 1 result
- Thymosin beta 4 and Fx, an actin-sequestering peptide, are indistinguishable.
Safer D · The Journal of biological chemistry · 1991
In vitro (cell-free) · 3 results
- The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.
Goldschmidt-Clermont PJ · Molecular biology of the cell · 1992
In vitro (cell-free) · 3 results
- Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering proteins.
Yu FX · The Journal of biological chemistry · 1993
In vitro (cell-free) · 5 results
- Profilin promotes barbed-end actin filament assembly without lowering the critical concentration.
Kang F · The Journal of biological chemistry · 1999
In vitro (cell-free) · 3 results
- Interaction of thymosin beta 4 with muscle and platelet actin: implications for actin sequestration in resting platelets.
Weber A · Biochemistry · 1992
In vitro (cell-free) · 8 results
- Thymosin beta 4 sequesters the majority of G-actin in resting human polymorphonuclear leukocytes.
Cassimeris L · The Journal of cell biology · 1992
In vitro (cell-free) · 5 results
- Modulation of the interaction between G-actin and thymosin beta 4 by the ATP/ADP ratio: possible implication in the regulation of actin dynamics.
Carlier MF · Proceedings of the National Academy of Sciences of the United States of America · 1993
In vitro (cell-free) · 3 results
- The actin binding site of thymosin beta 4 mapped by mutational analysis.
Van Troys M · The EMBO journal · 1996
In vitro (cell-free) · 5 results
- Thymosin beta 4 binds actin in an extended conformation and contacts both the barbed and pointed ends.
Safer D · Biochemistry · 1997
In vitro (cell-free) · 4 results
- Structural basis of thymosin-β4/profilin exchange leading to actin filament polymerization.
Xue B · Proceedings of the National Academy of Sciences of the United States of America · 2014
In vitro (cell-free) · 3 results
- Thymosin beta4 is released from human blood platelets and attached by factor XIIIa (transglutaminase) to fibrin and collagen.
Huff T · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2002
In vitro (cell-free) · 5 results
- Tbeta 4 is not a simple G-actin sequestering protein and interacts with F-actin at high concentration.
Carlier MF · The Journal of biological chemistry · 1996
In vitro (cell-free) · 5 results
- How a single residue in individual β-thymosin/WH2 domains controls their functions in actin assembly.
Didry D · The EMBO journal · 2012
In vitro (cell-free) · 2 results
- Interactions of beta-thymosins, thymosin beta 4-sulfoxide, and N-terminally truncated thymosin beta 4 with actin studied by equilibrium centrifugation, chemical cross-linking and viscometry.
Huff T · European journal of biochemistry · 1995
In vitro (cell-free) · 7 results
- Use of bimanyl actin derivative (TMB-actin) for studying complexation of beta-thymosins. Inhibition of actin polymerization by thymosin beta 9.
Heintz D · FEBS letters · 1993
In vitro (cell-free) · 2 results
- Formation and implications of a ternary complex of profilin, thymosin beta 4, and actin.
Yarmola EG · The Journal of biological chemistry · 2001
In vitro (cell-free) · 4 results
- Thymosin beta4 induces a conformational change in actin monomers.
Dedova IV · Biophysical journal · 2006
In vitro (cell-free) · 7 results
- Interaction of G-actin with thymosin beta 4 and its variants thymosin beta 9 and thymosin beta met9.
Jean C · Journal of muscle research and cell motility · 1994
In vitro (cell-free) · 5 results
- C-terminal variations in beta-thymosin family members specify functional differences in actin-binding properties.
Eadie JS · Journal of cellular biochemistry · 2000
In vitro (cell-free) · 3 results
- Mapping the ADF/cofilin binding site on monomeric actin by competitive cross-linking and peptide array: evidence for a second binding site on monomeric actin.
Mannherz HG · Journal of molecular biology · 2007
In vitro (cell-free) · 1 result
- Actin-sequestering ability of thymosin beta 4, thymosin beta 4 fragments, and thymosin beta 4-like peptides as assessed by the DNase I inhibition assay.
Hannappel E · Biological chemistry Hoppe-Seyler · 1993
In vitro (cell-free) · 4 results
- Mapping the binding site of thymosin beta4 on actin by competition with G-actin binding proteins indicates negative co-operativity between binding sites located on opposite subdomains of actin.
Ballweber E · The Biochemical journal · 1997
In vitro (cell-free) · 2 results
- Thymosin beta4: actin regulation and more.
Yarmola EG · Annals of the New York Academy of Sciences · 2007
In vitro (cell-free) · 7 results
- Effects of profilin and thymosin beta4 on the critical concentration of actin demonstrated in vitro and in cell extracts with a novel direct assay.
Yarmola EG · The Journal of biological chemistry · 2004
In vitro (cell-free) · 2 results
- Identification of contact sites in the actin-thymosin beta 4 complex by distance-dependent thiol cross-linking.
Reichert A · The Journal of biological chemistry · 1996
In vitro (cell-free) · 4 results
- The sulfoxide of thymosin beta 4 almost lacks the polymerization-inhibiting capacity for actin.
Heintz D · European journal of biochemistry · 1994
In vitro (cell-free) · 6 results
- A hypothalamic activator of calmodulin-dependent enzymes is thymosin beta 4 (1-39).
Galoyan AA · Neurochemical research · 1992
In vitro (cell-free) · rabbit · 5 results
- Multiple fuzzy interactions in the moonlighting function of thymosin-β4.
Tantos A · Intrinsically disordered proteins · 2013
In vitro (cell-free) · 1 result
- Factor XIIIa incorporates thymosin beta4 preferentially into the fibrin(ogen) alphaC-domains.
Makogonenko E · Biochemistry · 2004
In vitro (cell-free) · 6 results
- The N-terminal sequences (5-20) of thymosin beta 4 binds to monomeric actin in an alpha-helical conformation.
Feinberg J · Biochemical and biophysical research communications · 1996
In vitro (cell-free) · 2 results