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Study · In vitro (cells) · 2026

3 results

Understanding the effects of ciprofloxacin on corneal epithelial cells: a study using electric cell-substrate impedance sensing (ECIS) technology.

Banga L, Shawky M, Ebrahim F, Chowdhury R, Kuhl A, Ebrahim AS, Berger E

Experimental eye research10 Jul 2026

PMID42431294 (opens in a new tab)PMCIDPMC13477596 (opens in a new tab)DOI10.1016/j.exer.2026.111162 (opens in a new tab)PepBankPUB-42431294
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In corneal epithelial cells exposed to ciprofloxacin, Tβ4 improved wound healing.

    In plain wordsIn lab tests on corneal cells exposed to an antibiotic, Tβ4 improved wound healing.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseWound healing in CPFX-exposed corneal epithelial cells
    Study

    n: not reported in source

    corneal epithelial cells with CPFX
    Comparator
    CPFX alone
    Outcome group
    Wound healing · Eye
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although Tβ4 improved wound healing
    1 context sentence
    Summary · context
    Subsequently, an in vitro approach was used to elucidate the impact of CPFX on corneal epithelial cells, both alone and in combination with Tβ4.
  2. 02LabIn vitro (cells)Efficacy outcome

    In corneal epithelial cells exposed to ciprofloxacin, Tβ4 improved barrier function.

    In plain wordsIn lab tests on corneal cells exposed to an antibiotic, Tβ4 improved the cell barrier.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseBarrier function in CPFX-exposed corneal epithelial cells
    Study

    n: not reported in source

    corneal epithelial cells with CPFX
    Comparator
    CPFX alone
    Outcome group
    Wound healing · Eye
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although Tβ4 improved wound healing and barrier function
    1 context sentence
    Summary · context
    Subsequently, an in vitro approach was used to elucidate the impact of CPFX on corneal epithelial cells, both alone and in combination with Tβ4.
  3. 03LabIn vitro (cells)Efficacy outcome

    In corneal epithelial cells, Tβ4 did not fully mitigate the disruptive effects of ciprofloxacin on the cell monolayer.

    In plain wordsIn lab tests on corneal cells, Tβ4 did not fully undo the damage caused by the antibiotic.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    MixedMitigation of CPFX-induced monolayer disruption by Tβ4
    Study

    n: not reported in source

    corneal epithelial cells with CPFX
    Comparator
    CPFX alone
    Outcome group
    Wound healing · Eye
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although Tβ4 improved wound healing and barrier function, the disruptive effects of CPFX were not fully mitigated.
    1 context sentence
    Summary · context
    Subsequently, an in vitro approach was used to elucidate the impact of CPFX on corneal epithelial cells, both alone and in combination with Tβ4.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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