Peptides / Sexual health and hormones

Natural peptide · 10 amino acids · 1,182.3 Da

Gonadorelin (GnRH, LHRH)

Approved in United Kingdom, Germany +1Banned in sport

Gonadorelin is the drug form of GnRH (also called LHRH), the hormone that tells the pituitary to release LH and FSH. It is approved as a diagnostic test in the UK and Germany, and studies in people measured sex hormones and fertility. PepBank shows 107 results on gonadorelin from 30 studies in people, and 8 from animal and lab studies. The strongest evidence is a randomized trial in people. Data as of 2026-10-30.

Also known as GnRH, LH-RH, LHRH, ABBOTT-41070, AY-24031, Gonadoliberin and 12 more

10 amino acids, from first to lastXHWSYGLRPG

Evidence level: Some studies in people107 of 115 results come from studies in people.

Results in people

107

93% of 115 results

Results in animals

under 1% of 115 results

Results in lab cells

6% of 115 results

From computer models

0% of 115 results

Overview

Gonadorelin (GnRH, LHRH) at a glance

What it is	Natural peptide, 10 amino acids
Approval	Approved nationally in the UK, Germany and Japan
In sport	Banned in sport (WADA S2.2.1)
Studies	56 studies with results. 33 of them gave gonadorelin, with 115 results. 107 in people1 in animals7 in lab cells
Best study in people	Randomized controlled trial with 36 people (2022)
Clinical trials	14 registered: 4 active or planned, 6 with posted results
Community use	Keeping testicular size and function during testosterone therapy, often as a stand-in for hCG; Restarting natural production after a steroid cycle (post-cycle therapy, PCT); Fertility support or sperm production, often between cycles; Higher libido, testosterone and semen volume (goals named in questions)

The science

What is gonadorelin?

Gonadorelin is the drug form of the natural 10-residue hormone GnRH (LHRH), which tells the pituitary to release LH and FSH. It is approved as a diagnostic test in some countries, and its US human products are discontinued.

Amino acids in one chain

The history of gonadorelin

1981
The oldest paper on gonadorelin in PepBank is from 1981.
2005February
A registered trial of gonadorelin started (NCT00296465).

Gonadorelin (GnRH, LHRH) structure and chemistry

The key facts about the molecule. Long codes are in the closed section below.

Sequence, 10 amino acidsFrom the first amino acid to the last

X1HWSY5GL+RPG10

Darker means more water-repelling+ and − show charge in the bodyOutlined: changed amino acid

Structure

Gonadorelin (GnRH, LHRH) is a natural peptide of 10 amino acids, with no ring, 2 changed amino acids.

Formula

C₅₅H₇₅N₁₇O₁₃

Molecular weight

1,182.3 g/mol

CAS number

33515-09-2

Target

Gonadotropin-releasing hormone receptor (gene GNRHR): agonistEvidence: primary literature

Development

Wyeth-Ayerst (Factrel) and Ferring (Lutrepulse; Ferring also sells LHRH Ferring in Germany). Many academic groups run diagnostic and pump studies. Highest phase: past the trial stage (see status).

Identifiers

PubChem 638793, ChEMBL CHEMBL1007, UNII 9O7312W37G, DrugBank DB00644, KEGG D08027, IUPHAR 3786, UniProt P01148, PDB 9U4W

Full sequence, SMILES and InChIKey

Three-letter sequence
H-Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

InChIKey
XLXSAKCOAKORKW-AQJXLSMYSA-N

SMILES
CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)NC(=O)CNC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6

See charge, composition and 3D structure on the Scientific page

The evidence

What gonadorelin studies show

Results grouped by what the studies measured. Each card shows where its results come from.

Some studies in people107 of 115 results come from studies in people.

Sex hormones and fertility

89 results · 89 in people

In infant boys with an undescended testis, gonadorelin did not change LH levels compared with no treatment. Journal of pediatric urology, 2022

Top results

In infant boys with an undescended testis, gonadorelin did not change LH levels compared with no treatment. (Journal of pediatric urology, 2022)
In infant boys with an undescended testis, penile size grew similarly with and without gonadorelin. (Journal of pediatric urology, 2022)
In girls with suspected early puberty, a GnRH injection did not lower kisspeptin levels compared with placebo. (Journal of pediatric endocrinology & metabolism, 2025)

Bones and joints

3 results · 3 in people

In young men with hypogonadotropic hypogonadism, bone density in the lower spine rose after 6 months of pulsatile gonadorelin. International journal of endocrinology, 2015

Top results

In young men with hypogonadotropic hypogonadism, bone density in the lower spine rose after 6 months of pulsatile gonadorelin. (International journal of endocrinology, 2015)
In young men with hypogonadotropic hypogonadism, bone density at the femoral neck rose after 6 months of pulsatile gonadorelin. (International journal of endocrinology, 2015)
In young men with hypogonadotropic hypogonadism, bone density at the hip rose after 6 months of pulsatile gonadorelin. (International journal of endocrinology, 2015)

Weight and appetite

3 results · 3 in people

In girls with suspected early puberty, a GnRH analogue injection did not change acylated ghrelin levels compared with saline. Hormone research in paediatrics, 2022

Top results

In girls with suspected early puberty, a GnRH analogue injection did not change acylated ghrelin levels compared with saline. (Hormone research in paediatrics, 2022)
In young men with hypogonadotropic hypogonadism, body mass index rose after 6 months of pulsatile gonadorelin. (International journal of endocrinology, 2015)
In girls with suspected early puberty, a GnRH analogue injection did not change desacylated ghrelin levels compared with saline. (Hormone research in paediatrics, 2022)

Blood sugar

2 results · 2 in people

In young men with hypogonadotropic hypogonadism, fasting insulin fell after 6 months of pulsatile gonadorelin. International journal of endocrinology, 2015

Top results

In young men with hypogonadotropic hypogonadism, fasting insulin fell after 6 months of pulsatile gonadorelin. (International journal of endocrinology, 2015)
In young men with hypogonadotropic hypogonadism, an insulin resistance score fell after 6 months of pulsatile gonadorelin. (International journal of endocrinology, 2015)

Cholesterol and blood fats

1 result · 1 in people

In young men with hypogonadotropic hypogonadism, total cholesterol fell after 6 months of pulsatile gonadorelin. International journal of endocrinology, 2015

Top results

In young men with hypogonadotropic hypogonadism, total cholesterol fell after 6 months of pulsatile gonadorelin. (International journal of endocrinology, 2015)

All 56 gonadorelin studies by area Open the Scientific page

Key gonadorelin studies

Studies in people come first, then studies in animals and in the lab.

People
The safety of neoadjuvant hormonal treatment in infants with cryptorchidism
Fiala et al. 2022 · Journal of pediatric urology · 36 people · cited by 2
8 results
People
A Randomized Trial of the Effect of a GnRH Analogue Injection on Ghrelin Levels in Girls
Rodanaki et al. 2022 · Hormone research in paediatrics · 13 people · cited by 2
2 results
People
Effect of a GnRH injection on kisspeptin levels in girls with suspected precocious puberty: a randomized-controlled pilot study
Rodanaki et al. 2025 · Journal of pediatric endocrinology & metabolism : JPEM · 13 people · cited by 0
2 results
People
The Pulsatile Gonadorelin Pump Induces Earlier Spermatogenesis Than Cyclical Gonadotropin Therapy in Congenital Hypogonadotropic Hypogonadism Men
Zhang et al. 2019 · American journal of men's health · 28 people · cited by 13
5 results
People
[Pituitary response to GnRH analogue testing in girls with a polycystic ovary syndrome]
Wikiera et al. 2006 · Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych · 57 people · cited by 0
4 results

All 56 Gonadorelin (GnRH, LHRH) studies

Gonadorelin clinical trials

ClinicalTrials.gov lists 14 trials of gonadorelin. 4 are active or planned, and 6 have posted results. PepBank does not show trial results.

Solid bars are dates that happened. Hatched bars are planned dates. Data from ClinicalTrials.gov.

LutrePulse Hypogonadotropic Hypogonadism

Phase 3completed39 people

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH

Phase 2/3completed132 people

Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome

Phase 4status unknown78 planned

All 7 Gonadorelin (GnRH, LHRH) trials

Status and safety

Is gonadorelin approved?

FDA

United States

Discontinued

Discontinued.

EMA

European Union

Not approved

No approved medicine contains it.

WADA

Sport

Banned

On the 2026 Prohibited List, section S2.2.1.

Yes. Approved nationally in the UK, Germany and Japan. No FDA approval and no central EU authorisation (EMA). Banned in sport (WADA S2.2.1).

Laws and labels change, so check the regulator for the current status.

Gonadorelin side effects and safety

PepBank has 9 safety results from studies of gonadorelin. 9 of them come from studies in people.

Safety results from studies (9)

In men using the gonadorelin pump, a skin allergic reaction was a common side effect. (American journal of men's health, 2019)
In eight patients treated with pulsed intravenous GnRH, no complications were seen. (The Journal of reproductive medicine, 1985)
In women treated with pulsed GnRH, problems with placing the intravenous line occurred in 0% to 11% of cases, 7% on average. (American journal of obstetrics and gynecology, 1990)
In one 8-year-old girl with early puberty, gonadorelin acetate given into a vein caused a severe allergic reaction within minutes. (Journal of pediatric endocrinology & metabolism, 2015)
A woman with severe hypogonadotropic hypogonadism developed a skin reaction at the sites where LHRH was injected by pump. (American journal of obstetrics and gynecology, 1989)
In women treated with pulsed GnRH, the reported incidence of multiple pregnancy was 12%. (American journal of obstetrics and gynecology, 1990)
In this patient, a skin prick test reacted to LHRH but not to the vehicle. (American journal of obstetrics and gynecology, 1989)
In this patient, a radioallergosorbent test found no LHRH-reactive IgE antibodies. (American journal of obstetrics and gynecology, 1989)
In this patient, a blood test found antibody to LHRH, only of the IgE type. (American journal of obstetrics and gynecology, 1989)

See every safety result on the Scientific page

Doses studied (12 shown)

The doses that these studies used. They are not recommendations.

Dose as reported	Class	Species	Route	Duration	Design	Source
100 μg/m2	Human	human	Not reported	Not reported	Randomized trial in people · n = 13	Rodanaki 2022
100 microg	Human	human	subcutaneous	Not reported	Trial in people without random groups · n = 57	Wikiera 2006
100 micrograms	Human	human	intravenous	Not reported	Trial in people without random groups · n = 24	Mendelson 1989
80 micrograms	Human	human	intravenous	Not reported	Trial in people without random groups · n = 10	Vesper 1986
100 ng/kg per bolus every 90 minutes	Human	human	intravenous	two consecutive ovulatory cycles	Trial in people without random groups · n = 5	Corenthal 1994
100 µg	Human	human	intravenous	Not reported	Observational study · n = 67	Sansone 2021
0.1 mg	Human	human	intravenous	Not reported	Observational study · n = 37	Martin 2005
0.1 mg/m2	Human	human	intravenous	Not reported	Observational study · n = 32	Kauschansky 2002
60 microg/m2	Human	human	Not reported	Not reported	Observational study	Mitrović 2006
10 µg per 90 min	Human	human	pump	1 week	Reports of single patients · n = 5	Liu 2015
16 micrograms every 120 min	Human	human	subcutaneous	Not reported	Reports of single patients · n = 1	Iwabuchi 2021
50 mumol.L-1	Lab	rat	superfusion and/or bath application	Not reported	Study on tissue taken from a body · n = 29	Zhou 1996

From the community

How people use it

What people report online. It comes from forums and guides, not from studies.

Community-reported. Not tested in trials.

Sources report that men use compounded gonadorelin injections next to testosterone therapy, usually 100 to 200 mcg under the skin two to three times a week, to keep testicular size and function. Others use it after steroid cycles. The only label dose is a single 100 mcg diagnostic injection, and sources say the community schedules have not been tested as protocols.

Reported routines and cautions

What people use it for

Keeping testicular size and function during testosterone therapy, often as a stand-in for hCGS3S4S5S6
Restarting natural production after a steroid cycle (post-cycle therapy, PCT)S3S7S8S10
Fertility support or sperm production, often between cyclesS3S9S11S13
Higher libido, testosterone and semen volume (goals named in questions)S4S14

Reported regimens

Regimens that community sources report for Gonadorelin. Community-reported, not tested in trials.
Context	Route	Amount	How often	How long	Agreement	Sources
Diagnostic test of pituitary gonadotrope function (UK product label). It is a one-time test, not a treatment course.Official label dosing of an approved product	subcutaneous or intravenous injection	100 mcg per dose	single injection	one dose; blood samples for LH are drawn before and up to 120 minutes after	label	S1
Diagnostic test of the pituitary-gonadal axis (German product information, LHRH Ferring 0.1 mg/1 ml)Official label dosing of an approved product	intravenous bolus injection	25 to 100 mcg per dose	single dose; the text also names repeated stimulation a few hours apart or pulsatile infusion	Not stated	label	S2
Next to testosterone therapy, to keep testicular function (often used in place of hCG)	subcutaneous injection	100 to 200 mcg per dose	2 to 3 times weekly	ongoing, alongside testosterone therapy	2 sources agree on 100 mcg doses; S3 gives 100 to 200 mcg and 2 to 3 times weekly, S4 gives 100 mcg twice weekly. S3 carries seller rankings.	S3S4
Next to testosterone therapy: a clinic schedule with a much larger amount per injection	Not statedThe thread does not name the route.	1 to 2 mg per dose	twice weekly	Not stated	single source; the same poster gives two readings (2 mg per injection, or 1 mg per injection for 2 mg a week), so the amount runs from 1 to 2 mg	S5
Next to testosterone therapy: daily or twice-daily schedule in a dosing guide	subcutaneous injectionThe guide also lists intramuscular and intravenous.	100 to 400 mcg per dose	1 to 2 times daily	Not stated	single source; it differs from R3 (twice weekly) and says twice-weekly plans give almost no cumulative exposure	S6
After a steroid cycle (post-cycle therapy, PCT), to restart natural production	subcutaneous injection	100 to 200 mcg per dose	differs: daily (S7, S8, S10); every other day (S7); daily for 3 days, then 2 to 3 times weekly (S3)	2 to 4 weeks (S3); 7 to 14 days (one post in S7)	sources differ: most give 100 mcg, from 100 to 150 mcg; frequency runs from every other day to daily; duration is 1 to 4 weeks in the two sources that give one. S3 carries seller rankings and S7, S8, S10 carry seller links.	S3S7S8S10
Fertility support or testicle size around steroid cycles (starting amounts in replies)	Not statedThe replies do not name the route.	50 to 150 mcg per dose	differs: 2 to 3 times weekly (S11); every day (S13); every third day (S9)	Not stated	sources differ: 50 mcg daily (S13), 100 mcg twice or three times weekly (S11), 100 mcg every third day (S9). S9 and S11 carry seller links.	S9S11S13
Much larger amounts in forum replies (PCT or on cycle)	Not statedThe replies do not name the route.	0.5 to 2 mg per dose	daily or every other day	Not stated	sources differ widely from R3 and R6; each figure is one reply	S9S12

Reported side effects

acne and irritability in the first weeks, as hormones changedS4
injection-site stinging, flushing, light-headedness, headache, nausea and abdominal discomfortS6
rare in the label: tachycardia, nausea, abdominal discomfort, headache, dizziness, flushing, injection-site induration, urticaria and bronchospasm; rare hypersensitivity reactionsS1

Reported benefits (claims, not shown in trials)

testicle size came back within about 10 days on testosterone therapy (one patient report)S4
stronger libido (one patient report)S4
some users report keeping testicular function on testosterone therapy, others report continued shrinkageS3

Cautions

Gonadorelin acts on the pituitary and has a half-life of minutes. S3 says the community is increasingly skeptical that twice-weekly or three-times-weekly doses replace hCG for testicular function. S6 says its own plan is an extrapolation and not a studied protocol.S3S6
Sources differ on over-frequent dosing. S3 and S6 say frequent or continuous dosing can lower LH and FSH by desensitizing the receptor, and S3 says community protocols stop at 3 daily doses in a row. S6 also says this is essentially impossible at 'sane doses'.S3S6
Forum replies often say gonadorelin does not help PCT or fertility and name hCG or clomiphene instead. One poster says friends tried it with no success.S7S8S13
S3 says blood work (LH, FSH, testosterone, estradiol) is essential when using it.S3
One forum reply says to get it from an approved source because it is faked a lot.S8
The UK label lists known or suspected pregnancy as a contraindication, and says a dose in the follicular phase of a normal cycle may cause premature ovulation.S1

Status notes

No gonadorelin product for people is marketed in the US now. Drugs@FDA lists Factrel (NDA 018123, approved 1982) and Lutrepulse (NDA 019687, approved 1989) as discontinued, and the gonadorelin labels on DailyMed are for cattle.S16 S17 S18
Gonadorelin is not in any FDA 503A category (list updated 2026-05-14). It is in category 1 (under evaluation) of the 503B list (updated 2025-03-21), marked as a component of an FDA-approved drug. It was not on the agenda of the July 2026 FDA compounding advisory committee meeting.S19 S20 S21
Sources say clinics moved to gonadorelin after hCG, FSH and LH became biologics in March 2020 (S6, S3). A 2023 survey of US outsourcing pharmacies (S15) found that 13 had made compounded gonadotropins before March 2020, that 8 of them stopped, and that 6 of those 8 gave the 2020 rule as the reason. The survey is about hCG and FSH and does not mention gonadorelin.S6S3S15
WADA names gonadorelin in S2.2.1 (testosterone-stimulating peptides in males) in the 2026 List and in the 2027 List.S22
The UK and Germany have product information for a diagnostic gonadorelin injection (single 100 mcg adult dose).S1 S2

Community sources

S1Gonadorelin 100 micrograms powder for solution for injection (SmPC, PL 17509/0005) (opens in a new tab)medicines.org.uk
S2LHRH Ferring 0,1 mg/1 ml Injektionslösung (Rote Liste) (opens in a new tab)rote-liste.de
S3Gonadorelin: Community Protocols & Reportspeptideprotocolwiki.comcarries seller links, not linked
S4Gonadorelin Works For Me. But How?excelmale.comcarries seller links, not linked
S5Gonadorelin (thread, 2020)excelmale.comcarries seller links, not linked
S6Gonadorelin: Dosage, Half-Life & Reconstitution (opens in a new tab)jackedforums.com
S7gonadorelin for pct for recoveryanabolex.comcarries seller links, not linked
S8Gonadorelin subQ dosage helpanabolex.comcarries seller links, not linked
S9gonadorelin for boost in fertility and bigger nutsanabolex.comcarries seller links, not linked
S10Gonadorelin for pct planningelitefitness.comcarries seller links, not linked
S11Gonadorelin for fertility helpevolutionary.orgcarries seller links, not linked
S12Gonadorelin 1mgs a day worth it?musclechemistry.comcarries seller links, not linked
S13gonadorelin for reproductive health?musclechemistry.comcarries seller links, not linked
S14how to run gonadorelin?elitefitness.comcarries seller links, not linked
S15The availability of gonadotropin therapy from FDA-approved pharmacies for men with hypogonadism and infertility (opens in a new tab)pmc.ncbi.nlm.nih.gov
S16Drugs@FDA: NDA 018123 (Factrel) (opens in a new tab)accessdata.fda.gov
S17Drugs@FDA: NDA 019687 (Lutrepulse) (opens in a new tab)accessdata.fda.gov
S18DailyMed: Factrel (gonadorelin hydrochloride) injection, Zoetis (veterinary) (opens in a new tab)dailymed.nlm.nih.gov
S19FDA: bulk drug substances nominated for 503A (updated 2026-05-14) (opens in a new tab)fda.gov
S20FDA: bulk drug substances nominated for 503B (updated 2025-03-21) (opens in a new tab)fda.gov
S21FDA: July 23-24, 2026 Pharmacy Compounding Advisory Committee meeting (opens in a new tab)fda.gov
S22WADA 2026 Prohibited List (opens in a new tab)wada-ama.org

plus 1 seller page (not linked)

Gaps

No Reddit page was used, because Reddit cannot be fetched. A T Nation thread (clinic gave 2 injections a week, no amount) could not be quote-checked and was dropped. No Longecity, ThinkSteroids or Meso-Rx page with gonadorelin amounts was found. No US human label exists (Drugs@FDA holds none, DailyMed lists only veterinary labels), so the label regimens come from the UK SmPC and the German Rote Liste text. The old Lutrepulse pump dose (5 mcg every 90 minutes) was found only on drug reference sites, not on a label page, so it is not written as a regimen. Most community amounts are replies to questions, not reports of finished courses. Eleven of the community sources carry seller rankings or seller links (affiliate), and S3 may copy forum posts. Some forum posts mix up units (mcg and mg) or give 'EOD' for every other day. Nasal and other routes were not found with a quotable amount. The sources do not say how long people stay on gonadorelin next to testosterone therapy beyond 'ongoing'. No source gave a measured result such as LH, sperm count or testicular volume except one poster's LH value of 2.1 mIU/mL 90 minutes after 100 mcg in S4 (not used as a regimen fact).

Questions and more

Ask a question about gonadorelin

The answer links to every study it uses.

What does the evidence say about gonadorelin?Is gonadorelin tested in people?Compare with Triptorelin (Trelstar, Decapeptyl)Compare with Oxytocin

Sources

Database: PepBank data for gonadorelin (data version 308560)
Regulator: FDA status record
Regulator: EMA status record
Regulator: WADA status record
Trial registry: ClinicalTrials.gov
Community: community sources (forums and guides), as summarized in the PepBank community file

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

PepBank is a research reference. Talk to a doctor before you use any peptide.

Ask your AI about gonadorelin

Curo is a peptide shop. PepBank and Curo have the same owner. See the Curo catalog (opens in a new tab).

Gonadorelin (GnRH, LHRH)

Approved in United Kingdom, Germany +1Banned in sport

Also known as GnRH, LH-RH, LHRH, ABBOTT-41070, AY-24031, Gonadoliberin and 12 more

What it is

Natural peptide, 10 amino acids

Approval

Approved nationally in the UK, Germany and Japan

In sport

Banned in sport (WADA S2.2.1)

Studies

56 studies with results. 33 of them gave gonadorelin, with 115 results.
107 in people1 in animals7 in lab cells

Best study in people

Randomized controlled trial with 36 people (2022)

Clinical trials

14 registered: 4 active or planned, 6 with posted results

Community use

Keeping testicular size and function during testosterone therapy, often as a stand-in for hCG; Restarting natural production after a steroid cycle (post-cycle therapy, PCT); Fertility support or sperm production, often between cycles; Higher libido, testosterone and semen volume (goals named in questions)

Dose as reported

Class

Species

Route

Duration

Design

Source

100 μg/m2

Human

human

Not reported

Randomized trial in people · n = 13

Rodanaki 2022

100 microg

Human

human

subcutaneous

Not reported

Trial in people without random groups · n = 57

Wikiera 2006

100 micrograms

Human

human

intravenous

Not reported

Trial in people without random groups · n = 24

Mendelson 1989

80 micrograms

Human

human

intravenous

Not reported

Trial in people without random groups · n = 10

Vesper 1986

100 ng/kg per bolus every 90 minutes

Human

human

intravenous

two consecutive ovulatory cycles

Trial in people without random groups · n = 5

Corenthal 1994

100 µg

Human

human

intravenous

Not reported

Observational study · n = 67

Sansone 2021

0.1 mg

Human

human

intravenous

Not reported

Observational study · n = 37

Martin 2005

0.1 mg/m2

Human

human

intravenous

Not reported

Observational study · n = 32

Kauschansky 2002

60 microg/m2

Human

human

Not reported

Observational study

Mitrović 2006

10 µg per 90 min

Human

human

pump

1 week

Reports of single patients · n = 5

Liu 2015

16 micrograms every 120 min

Human

human

subcutaneous

Not reported

Reports of single patients · n = 1

Iwabuchi 2021

50 mumol.L-1

Lab

rat

superfusion and/or bath application

Not reported

Study on tissue taken from a body · n = 29

Zhou 1996

Context

Route

Amount

How often

How long

Agreement

Sources

Diagnostic test of pituitary gonadotrope function (UK product label). It is a one-time test, not a treatment course.Official label dosing of an approved product

subcutaneous or intravenous injection

100 mcg per dose

single injection

one dose; blood samples for LH are drawn before and up to 120 minutes after

label

Diagnostic test of the pituitary-gonadal axis (German product information, LHRH Ferring 0.1 mg/1 ml)Official label dosing of an approved product

intravenous bolus injection

25 to 100 mcg per dose

single dose; the text also names repeated stimulation a few hours apart or pulsatile infusion

Not stated

label

Next to testosterone therapy, to keep testicular function (often used in place of hCG)

subcutaneous injection

100 to 200 mcg per dose

2 to 3 times weekly

ongoing, alongside testosterone therapy

2 sources agree on 100 mcg doses; S3 gives 100 to 200 mcg and 2 to 3 times weekly, S4 gives 100 mcg twice weekly. S3 carries seller rankings.

S3S4

Next to testosterone therapy: a clinic schedule with a much larger amount per injection

Not statedThe thread does not name the route.

1 to 2 mg per dose

twice weekly

Not stated

single source; the same poster gives two readings (2 mg per injection, or 1 mg per injection for 2 mg a week), so the amount runs from 1 to 2 mg

Next to testosterone therapy: daily or twice-daily schedule in a dosing guide

subcutaneous injectionThe guide also lists intramuscular and intravenous.

100 to 400 mcg per dose

1 to 2 times daily

Not stated

single source; it differs from R3 (twice weekly) and says twice-weekly plans give almost no cumulative exposure

After a steroid cycle (post-cycle therapy, PCT), to restart natural production

subcutaneous injection

100 to 200 mcg per dose

differs: daily (S7, S8, S10); every other day (S7); daily for 3 days, then 2 to 3 times weekly (S3)

2 to 4 weeks (S3); 7 to 14 days (one post in S7)

sources differ: most give 100 mcg, from 100 to 150 mcg; frequency runs from every other day to daily; duration is 1 to 4 weeks in the two sources that give one. S3 carries seller rankings and S7, S8, S10 carry seller links.

S3S7S8S10

Fertility support or testicle size around steroid cycles (starting amounts in replies)

Not statedThe replies do not name the route.

50 to 150 mcg per dose

differs: 2 to 3 times weekly (S11); every day (S13); every third day (S9)

Not stated

sources differ: 50 mcg daily (S13), 100 mcg twice or three times weekly (S11), 100 mcg every third day (S9). S9 and S11 carry seller links.

S9S11S13

Much larger amounts in forum replies (PCT or on cycle)

Not statedThe replies do not name the route.

0.5 to 2 mg per dose

daily or every other day

Not stated

sources differ widely from R3 and R6; each figure is one reply

S9S12

Gonadorelin (GnRH, LHRH)

Gonadorelin (GnRH, LHRH) at a glance

What is gonadorelin?

The history of gonadorelin

Gonadorelin (GnRH, LHRH) structure and chemistry

What gonadorelin studies show

Sex hormones and fertility

Bones and joints

Weight and appetite

Blood sugar

Cholesterol and blood fats

Key gonadorelin studies

Gonadorelin clinical trials

Is gonadorelin approved?

Gonadorelin side effects and safety

How people use it

What people use it for

Reported regimens

Reported side effects

Reported benefits (claims, not shown in trials)

Cautions

Status notes

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Gonadorelin (GnRH, LHRH)

Gonadorelin (GnRH, LHRH) at a glance

What is gonadorelin?

The history of gonadorelin

Gonadorelin (GnRH, LHRH) structure and chemistry

What gonadorelin studies show

Sex hormones and fertility

Bones and joints

Weight and appetite

Blood sugar

Cholesterol and blood fats

Key gonadorelin studies

Gonadorelin clinical trials

Is gonadorelin approved?

Gonadorelin side effects and safety

How people use it

What people use it for

Reported regimens

Reported side effects

Reported benefits (claims, not shown in trials)

Cautions

Status notes

Community sources

Ask a question about gonadorelin

Related peptides

Sources