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Study · Randomized controlled trial · n = 13 · 2022

2 results

A Randomized Trial of the Effect of a GnRH Analogue Injection on Ghrelin Levels in Girls.

Rodanaki M, Rask E, Lodefalk M

Hormone research in paediatrics27 Jul 2022Cited by 2 (Europe PMC)

PMID35896083 (opens in a new tab)DOI10.1159/000526147 (opens in a new tab)PepBankPUB-35896083
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In girls with suspected central precocious puberty, acylated ghrelin levels did not change after GnRH analogue injection compared with saline.

    In plain wordsIn girls with suspected early puberty, a GnRH analogue injection did not change acylated ghrelin levels compared with saline.

    Peptide
    Gonadorelin (GnRH, LHRH)
    Outcome
    No significant changeAcylated ghrelin level after GnRH analogue injection
    Study

    n = 13

    Comparator
    Saline
    Outcome group
    Appetite and food intake · Endocrine and hormones
    Studied dose
    100 μg/m2As given in this study (human).

    Source sentences

    Summary
    Neither AG nor DAG levels changed after GnRH analogue injection in comparison to saline.
    2 context sentences
    Summary · context
    In this randomized, placebo-controlled, cross-over study, 13 girls with suspected central precocious puberty were included.
    Summary · context
    They performed an adjusted GnRH stimulation test twice and were given Relefact LHRH® (100 μg/m2) or saline in a randomized order.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In girls with suspected central precocious puberty, desacylated ghrelin levels did not change after GnRH analogue injection compared with saline.

    In plain wordsIn girls with suspected early puberty, a GnRH analogue injection did not change desacylated ghrelin levels compared with saline.

    Peptide
    Gonadorelin (GnRH, LHRH)
    Outcome
    No significant changeDesacylated ghrelin level after GnRH analogue injection
    Study

    n = 13

    Comparator
    Saline
    Outcome group
    Appetite and food intake · Endocrine and hormones
    Studied dose
    100 μg/m2As given in this study (human).

    Source sentences

    Summary
    Neither AG nor DAG levels changed after GnRH analogue injection in comparison to saline.
    2 context sentences
    Summary · context
    In this randomized, placebo-controlled, cross-over study, 13 girls with suspected central precocious puberty were included.
    Summary · context
    They performed an adjusted GnRH stimulation test twice and were given Relefact LHRH® (100 μg/m2) or saline in a randomized order.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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