MK-677 (ibutamoren) studies: 90 papers with results
Page 2 of 2
- Expression of functional growth hormone secretagogue receptors in human pituitary adenomas: polymerase chain reaction, triple in-situ hybridization and cell culture studies.
Barlier A · Journal of neuroendocrinology · 1999
In vitro (cells) · 7 results
- Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.
Baldanzi G · The Journal of cell biology · 2002
In vitro (cells) · 7 results
- Identification, characterization, and biological activity of specific receptors for natural (ghrelin) and synthetic growth hormone secretagogues and analogs in human breast carcinomas and cell lines.
Cassoni P · The Journal of clinical endocrinology and metabolism · 2001
In vitro (cells) · 4 results
- Ghrelin and des-acyl ghrelin both inhibit isoproterenol-induced lipolysis in rat adipocytes via a non-type 1a growth hormone secretagogue receptor.
Muccioli G · European journal of pharmacology · 2004
In vitro (cells) · rat · 6 results
- Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling.
Holst B · Molecular endocrinology (Baltimore, Md.) · 2005
In vitro (cells) · 10 results
- The antiproliferative effect of synthetic peptidyl GH secretagogues in human CALU-1 lung carcinoma cells.
Ghè C · Endocrinology · 2002
In vitro (cells) · 7 results
- Natural (ghrelin) and synthetic (hexarelin) GH secretagogues stimulate H9c2 cardiomyocyte cell proliferation.
Pettersson I · The Journal of endocrinology · 2002
In vitro (cells) · 6 results
- Adenosine: A partial agonist of the growth hormone secretagogue receptor.
Smith RG · Biochemical and biophysical research communications · 2000
In vitro (cells) · 2 results
- Pharmacological characterisation of a new oral GH secretagogue, NN703.
Hansen BS · European journal of endocrinology · 1999
In vitro (cells) · 6 results
- Hexarelin protects H9c2 cardiomyocytes from doxorubicin-induced cell death.
Filigheddu N · Endocrine · 2001
In vitro (cells) · 5 results
- Ghrelin Aggravates Prostate Enlargement in Rats with Testosterone-Induced Benign Prostatic Hyperplasia, Stromal Cell Proliferation, and Smooth Muscle Contraction in Human Prostate Tissues.
Wang X · Oxidative medicine and cellular longevity · 2019
In vitro (cells) · 3 results
- Antiviral activity of sertindole, raloxifene and ibutamoren against transcription and replication-competent Ebola virus-like particles.
Yoon YS · BMB reports · 2020
In vitro (cells) · 7 results
- Investigating the P53-dependent anti-cancer effect of ibutamoren in human cancer cell lines.
Abdul Ghafoor N · Basic & clinical pharmacology & toxicology · 2025
In vitro (cells) · 6 results
- Binding of 125I-labeled ghrelin to membranes from human hypothalamus and pituitary gland.
Muccioli G · Journal of endocrinological investigation · 2001
In vitro (cell-free) · 2 results
- Growth hormone secretagogues and growth hormone releasing peptides act as orthosteric super-agonists but not allosteric regulators for activation of the G protein Galpha(o1) by the Ghrelin receptor.
Bennett KA · Molecular pharmacology · 2009
In vitro (cell-free) · 10 results
- Evidence against adenosine analogues being agonists at the growth hormone secretagogue receptor.
Johansson S · Biochemical pharmacology · 2005
In vitro (cell-free) · 1 result
- Novel domain-selective ACE-inhibiting activity of synthetic growth hormone secretagogues.
Torsello A · Pharmacological research · 2012
In vitro (cell-free) · 5 results
- Characterization of equine liver microsome-generated metabolites of growth hormone secretagogue small molecule ibutamoren.
Philip M · Rapid communications in mass spectrometry : RCM · 2021
In vitro (cell-free) · horse · 8 results
- LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report.
Cardaci TD · Experimental physiology · 2022
Not a test of MK-677 (ibutamoren) alone · 26 results
- Rapid and harmonized analytical workflow for the determination of peptidic and non-peptidic doping agents in dried and liquid blood matrices.
Mazzarino M · The Analyst · 2026
Not a test of MK-677 (ibutamoren) alone · 21 results
- Identification of a new G-protein-linked receptor for growth hormone secretagogues.
Pong SS · Molecular endocrinology (Baltimore, Md.) · 1996
Not a test of MK-677 (ibutamoren) alone · 15 results
- Development and validation of SARMs and metabolic modulators screening in hair using UHPLC-MS/MS: Application to a doping case and first identification of S23 in authentic human hair.
Gheddar L · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2021
Not a test of MK-677 (ibutamoren) alone · 7 results
- Determination of a novel growth hormone secretagogue (MK-677) in human plasma at picogram levels by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry.
Constanzer ML · Journal of chromatography. B, Biomedical sciences and applications · 1997
Not a test of MK-677 (ibutamoren) alone · 6 results
- Solubilization and characterization of a growth hormone secretagogue receptor from porcine anterior pituitary membranes.
Pomés A · Biochemical and biophysical research communications · 1996
Not a test of MK-677 (ibutamoren) alone · 7 results
- Somatostatin receptor subtype 2 knockout mice are refractory to growth hormone-negative feedback on arcuate neurons.
Zheng H · Molecular endocrinology (Baltimore, Md.) · 1997
Not a test of MK-677 (ibutamoren) alone · 5 results
- Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues.
Feighner SD · Molecular endocrinology (Baltimore, Md.) · 1998
Not a test of MK-677 (ibutamoren) alone · 4 results
- Overlapping binding site for the endogenous agonist, small-molecule agonists, and ago-allosteric modulators on the ghrelin receptor.
Holst B · Molecular pharmacology · 2009
Not a test of MK-677 (ibutamoren) alone · 9 results
- Reversible Gynecomastia and Hypogonadism Due to Usage of Commercial Performance-Enhancing Supplement Use.
Chong S · JCEM case reports · 2024
Not a test of MK-677 (ibutamoren) alone · 4 results
- Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren.
Liu H · Nature communications · 2021
Not a test of MK-677 (ibutamoren) alone · 3 results
- Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer's disease.
Tian J · Science translational medicine · 2019
Not a test of MK-677 (ibutamoren) alone · 3 results
- Adenosine is an agonist of the growth hormone secretagogue receptor.
Tullin S · Endocrinology · 2000
Not a test of MK-677 (ibutamoren) alone · 2 results
- Thyroid hormone modulates food intake and glycemia via ghrelin secretion in Zucker fatty rats.
Patel K · Drug research · 2014
Not a test of MK-677 (ibutamoren) alone · 2 results
- Spontaneous Splenic Rupture in a Patient With Recent Use of Performance-Enhancing Compounds: A Case Report and Literature Review.
Jaffry K · Cureus · 2026
Not a test of MK-677 (ibutamoren) alone · 2 results
- Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.
McKee KK · Molecular endocrinology (Baltimore, Md.) · 1997
Not a test of MK-677 (ibutamoren) alone · 1 result
- Oxindole derivatives as orally active potent growth hormone secretagogues.
Tokunaga T · Journal of medicinal chemistry · 2001
Not a test of MK-677 (ibutamoren) alone · 1 result
- Pharmacological profile of a new orally active growth hormone secretagogue, SM-130686.
Nagamine J · The Journal of endocrinology · 2001
Not a test of MK-677 (ibutamoren) alone · 1 result
- Attenuation of the growth hormone secretagogue induction of Fos protein in the rat arcuate nucleus by central somatostatin action.
Dickson SL · Neuroendocrinology · 1997
Not a test of MK-677 (ibutamoren) alone · 3 results
- Development and validation of liquid chromatography-tandem mass spectrometry method for screening six selective androgen receptor modulators in dietary supplements.
Lee JH · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment · 2021
Not a test of MK-677 (ibutamoren) alone · 1 result
- SARMs, Metabolic Modulators and Growth Hormone Secretagogues in Suspected Illegal Medicines, Bought as Sport Performance Enhancers: A Retro- and Prospective Study Within the GEON.
Barrios MM · Drug testing and analysis · 2025
Not a test of MK-677 (ibutamoren) alone · 1 result
- Two methods for the measurement of the dissociation pressure of a crystalline hydrate.
Crocker LS · Journal of pharmaceutical and biomedical analysis · 1997
Not a test of MK-677 (ibutamoren) alone · 1 result