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Study · Not a test of the peptide alone · 1997

1 result

Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.

McKee KK, Palyha OC, Feighner SD, Hreniuk DL, Tan CP, Phillips MS, Smith RG, Van der Ploeg LH, Howard AD

Molecular endocrinology (Baltimore, Md.)1 Apr 1997Cited by 249 (Europe PMC)

PMID9092793 (opens in a new tab)DOI10.1210/mend.11.4.9908 (opens in a new tab)PepBankPUB-09092793
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, MK-677 (ibutamoren) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking MK-677 (ibutamoren).

  1. 01LabNot a test of MK-677 (ibutamoren) aloneIn vitro (cells)Activity measurement

    In lab tests, cloned rat GHS-R bound radiolabelled MK-0677 with high affinity.

    In plain wordsIn lab tests, cloned rat GHS-R bound radiolabelled MK-0677 with high affinity.

    Peptide
    MK-677 (ibutamoren)
    Outcome
    Not applicableCloned rat receptor binding affinity
    Study

    n: not reported in source

    HEK-293 cells
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Measurements

    K(D)
    0.7 nM
    cloned rat GHS-R

    Source sentences

    Summary
    The cloned rat GHS-R binds [35S]MK-0677 with high affinity [dissociation constant (K(D)) = 0.7 nM] and is functionally active when expressed in HEK-293 cells.

    In this study, MK-677 (ibutamoren) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MK-677 (ibutamoren).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 2

    14 Oct 2026, 01:46 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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