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Study · Not a test of the peptide alone · 2000

2 results

Adenosine is an agonist of the growth hormone secretagogue receptor.

Tullin S, Hansen BS, Ankersen M, Møller J, Von Cappelen KA, Thim L

Endocrinology1 Sept 2000Cited by 45 (Europe PMC)

PMID10965912 (opens in a new tab)DOI10.1210/endo.141.9.7631 (opens in a new tab)PepBankPUB-10965912
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, MK-677 (ibutamoren) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking MK-677 (ibutamoren).

  1. 01LabNot a test of MK-677 (ibutamoren) aloneIn vitro (cell-free)Activity measurement

    In receptor-expressing cell membranes, MK-0677 and adenosine had nearly identical binding capacities.

    In plain wordsIn lab tests, MK-0677 and adenosine had nearly identical receptor binding capacities.

    Peptide
    MK-677 (ibutamoren)
    Outcome
    No significant changeReceptor binding capacity
    Study

    n: not reported in source

    Membranes from cells expressing recombinant human GHS-R
    Comparator
    Adenosine
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Measurements

    Bmax
    2 x 10(-10) mol/mg protein
    MK-0677

    Source sentences

    Summary
    Binding experiments show that adenosine and the GHS compound MK-0677 bind to membranes from GHS-R expressing cells with nearly identical Bmax values (2.6 +/- 0.1 x 10(-10) mol/mg protein for adenosine and 2.0 +/- 0.3 x 10(-10) mol/mg protein for MK-0677).

    In this study, MK-677 (ibutamoren) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MK-677 (ibutamoren).

  2. 02LabNot a test of MK-677 (ibutamoren) aloneIn vitro (cell-free)Activity measurement

    In nontransfected cell membranes, no MK-0677 binding was detected.

    In plain wordsIn lab tests, MK-0677 showed no detectable binding to membranes from nontransfected cells.

    Peptide
    MK-677 (ibutamoren)
    Outcome
    Not applicableBinding in nontransfected membranes
    Study

    n: not reported in source

    Membranes from nontransfected cells
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    However, no binding to membranes from nontransfected cells could be detected.
    1 context sentence
    Summary · context
    Binding experiments show that adenosine and the GHS compound MK-0677 bind to membranes from GHS-R expressing cells with nearly identical Bmax values (2.6 +/- 0.1 x 10(-10) mol/mg protein for adenosine and 2.0 +/- 0.3 x 10(-10) mol/mg protein for MK-0677).

    In this study, MK-677 (ibutamoren) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MK-677 (ibutamoren).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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