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Study · Not a test of the peptide alone · 2014

2 results

Thyroid hormone modulates food intake and glycemia via ghrelin secretion in Zucker fatty rats.

Patel K, Joharapurkar A, Dhanesha N, Patel V, Kshirsagar S, Raval P, Raval S, Jain MR

Drug research19 Dec 2013Cited by 7 (Europe PMC)

PMID24357139 (opens in a new tab)DOI10.1055/s-0033-1363222 (opens in a new tab)PepBankPUB-24357139
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, MK-677 (ibutamoren) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking MK-677 (ibutamoren).

  1. 01AnimalNot a test of MK-677 (ibutamoren) aloneAnimal study (in vivo)Efficacy outcome

    In Zucker fatty rats, oral T3 with central MK-0677 produced an additive appetite effect.

    In plain wordsIn rats, oral T3 with central MK-0677 produced an additive increase in appetite.

    Peptide
    MK-677 (ibutamoren)
    Outcome
    IncreaseAppetite
    Study

    ratn: not reported in source

    Zucker fatty rats
    Outcome group
    Appetite and food intake · Metabolic and weight

    Source sentences

    Summary
    An additive effect on appetite and glucose was observed when T3 (oral) was administered with central (intracerebroventricular) administration of a ghrelin mimetic, MK-0677.
    1 context sentence
    Summary · context
    We investigated whether T3 influences appetite and glucose homeostasis by modulating circulating ghrelin, an important orexigenic hormone, in Zucker fatty rats.

    In this study, MK-677 (ibutamoren) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MK-677 (ibutamoren).

  2. 02AnimalNot a test of MK-677 (ibutamoren) aloneAnimal study (in vivo)Efficacy outcome

    In Zucker fatty rats, oral T3 with central MK-0677 produced an additive glucose effect.

    In plain wordsIn rats, oral T3 with central MK-0677 produced an additive increase in glucose.

    Peptide
    MK-677 (ibutamoren)
    Outcome
    IncreaseGlucose
    Study

    ratn: not reported in source

    Zucker fatty rats
    Outcome group
    Glycemic control · Metabolic and weight

    Source sentences

    Summary
    An additive effect on appetite and glucose was observed when T3 (oral) was administered with central (intracerebroventricular) administration of a ghrelin mimetic, MK-0677.
    1 context sentence
    Summary · context
    We investigated whether T3 influences appetite and glucose homeostasis by modulating circulating ghrelin, an important orexigenic hormone, in Zucker fatty rats.

    In this study, MK-677 (ibutamoren) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MK-677 (ibutamoren).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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