Peptides / Immune and antimicrobial

Mixture

Thymalin

Approved in RussiaNot banned in sport

Thymalin is a medicine made from thymus extract, a mix of peptides, and it is approved in Russia. Studies in people tested it on the immune system and blood clotting, and most results come from animal studies. PepBank shows 76 results on Thymalin from 26 studies in people, and 166 from animal and lab studies. The strongest evidence is a trial in people without random groups. Data as of 2026-10-30.

Also known as Thymaline, Timalin, Тималин

Evidence level: Some studies in people76 of 242 results come from studies in people.

Results in people

31% of 242 results

Results in animals

146

60% of 242 results

Results in lab cells

8% of 242 results

From computer models

0% of 242 results

Overview

Thymalin at a glance

What it is	Mixture
Approval	Approved in Russia only (registered as Thymalin / Тималин)
In sport	Not listed as banned by WADA
Studies	161 studies with results. 85 of them gave Thymalin, with 242 results. 76 in people146 in animals20 in lab cells
Best study in people	Non-randomized trial with 116 people (1989)
Clinical trials	None registered
Community use	Community immune and aging use

The science

What is Thymalin?

Russian registered thymus-extract medicine with a mixture of peptide components.

242

Study results in PepBank

Thymalin structure and chemistry

The key facts about the molecule. Long codes are in the closed section below.

Structure

Thymalin is a mixture, with no ring, no changed amino acids.

Development

Samson-Med (manufacturer). Highest phase: past the trial stage (see status).

See charge, composition and 3D structure on the Scientific page

The evidence

What Thymalin studies show

Results grouped by what the studies measured. Each card shows where its results come from.

Some studies in people76 of 242 results come from studies in people.

Immune system and inflammation

116 results · 45 in people · 57 animal · 14 lab

In tuberculosis patients, thymalin with chemotherapy restored cellular immune measures compared with control treatment. Vrachebnoe delo, 1989

Top results

In tuberculosis patients, thymalin with chemotherapy restored cellular immune measures compared with control treatment. (Vrachebnoe delo, 1989)
In patients with COVID-19, thymalin with standard therapy lowered IL-6, C-reactive protein and D-dimer faster than standard therapy alone. (Stem cell reviews and reports, 2021)
In pulmonary disease patients with preserved phagocytic function, thymalin improved the disease course compared with control treatment. (Terapevticheskii arkhiv, 1989)

Blood and clotting

22 results · 9 in people · 11 animal · 2 lab

In patients with periodontosis, thymaline returned blood clotting to normal. Farmakologiia i toksikologiia, 1984

Top results

In patients with periodontosis, thymaline returned blood clotting to normal. (Farmakologiia i toksikologiia, 1984)
In patients with severe COVID-19, Thymalin reduced blood fibrinogen. (Advances in gerontology = Uspekhi gerontologii, 2022)
In patients with lung abscess, added Timalin normalized clot breakdown activity faster than traditional treatment. (Khirurgiia, 2012)

Survival and serious illness

10 results · 5 in people · 5 animal

In older people, mortality was 2.0-2.1-fold lower in the Thymalin group than control during observation. Neuro endocrinology letters, 2003

Top results

In older people, mortality was 2.0-2.1-fold lower in the Thymalin group than control during observation. (Neuro endocrinology letters, 2003)
In patients with severe burns, thymalin treatment was linked to 11 days shorter hospital stay. (Vestnik khirurgii imeni I. I. Grekova, 2000)
In patients with severe COVID-19, Thymalin reduced blood lactate dehydrogenase. (Advances in gerontology = Uspekhi gerontologii, 2022)

Infections

7 results · 3 in people · 4 animal

In children with herpes stomatitis, thymalin did not rapidly relieve acute symptoms. Stomatologiia, 1994

Top results

In children with herpes stomatitis, thymalin did not rapidly relieve acute symptoms. (Stomatologiia, 1994)
In tuberculosis patients, thymalin with chemotherapy improved treatment efficacy earlier than control treatment. (Vrachebnoe delo, 1989)
In children at high risk of recurrent stomatitis, thymalin helped achieve a stable effect against recurrence. (Stomatologiia, 1994)

Cancer

7 results · 2 in people · 5 animal

In women with advanced cervical cancer, adding thymalin to radiotherapy allowed wider use of radical surgery than radiotherapy alone. Voprosy onkologii, 1991

Top results

In women with advanced cervical cancer, adding thymalin to radiotherapy allowed wider use of radical surgery than radiotherapy alone. (Voprosy onkologii, 1991)
In rats with transplanted tumors, Thymalin stopped tumor growth and produced regression in more than half of animals. (Bulletin of experimental biology and medicine, 2018)
In women with advanced cervical cancer, adding thymalin to radiotherapy improved treatment results compared with radiotherapy alone. (Voprosy onkologii, 1991)

Daily life and fitness

3 results · 2 in people · 1 animal

In patients with idiopathic parkinsonism, tremor, stiffness and slowed movement showed a positive course during thymalin treatment. Likars'ka sprava, 1999

Top results

In patients with idiopathic parkinsonism, tremor, stiffness and slowed movement showed a positive course during thymalin treatment. (Likars'ka sprava, 1999)
In patients with idiopathic parkinsonism, general physical and mental well-being improved during thymalin treatment. (Likars'ka sprava, 1999)
In mixed human and animal studies of radiation injury, thymalin reduced weakness. (Arkhiv patologii, 1993)

All 161 Thymalin studies by area Open the Scientific page

Key Thymalin studies

Studies in people come first, then studies in animals and in the lab.

People
[The use of thymalin in the combined chemotherapy of patients with infiltrative destructive pulmonary tuberculosis]
Ivanova et al. 1989 · Vrachebnoe delo · 116 people · cited by 0
2 results
People
[Dynamics of immunological indices in patients with chronic viral hepatitis B and the effect of thymalin therapy]
Gol'zand et al. 1986 · Zhurnal mikrobiologii, epidemiologii i immunobiologii · 102 people · cited by 0
6 results
People
[The use of thymalin in the combined treatment of patients with disseminated cancer of the cervix uteri]
Vishnevskaia et al. 1991 · Voprosy onkologii · 96 people · cited by 0
2 results
People
[A comparative evaluation of the efficacy of immunocorrection in children with bronchial asthma living in ecologically contrasted regions]
Trishina et al. 1995 · Likars'ka sprava · 50 people · cited by 0
1 result
People
[Differentiated immunocorrective therapy in nonspecific ulcerative colitis]
Tkach et al. 1992 · Likars'ka sprava · 50 people · cited by 0
1 result

All 161 Thymalin studies

Thymalin clinical trials

ClinicalTrials.gov lists no trial of Thymalin. A trial under another name may exist.

Status and safety

Is Thymalin approved?

FDA

United States

Not approved

No approved medicine contains it.

EMA

European Union

Not approved

No approved medicine contains it.

WADA

Sport

Not banned

Not on the 2026 Prohibited List.

Yes. Approved in Russia only (registered as Thymalin / Тималин). No FDA approval and no central EU authorisation (EMA). Not listed as banned by WADA.

Laws and labels change, so check the regulator for the current status.

Thymalin side effects and safety

PepBank has 4 safety results from studies of Thymalin. 3 of them come from studies in people.

Safety results from studies (4)

In older people, mortality was 2.0-2.1-fold lower in the Thymalin group than control during observation. (Neuro endocrinology letters, 2003)
In patients with severe COVID-19, hospital mortality was lower with Thymalin than with basic therapy. (Advances in gerontology = Uspekhi gerontologii, 2022)
In patients with severe COVID-19, hospital mortality was lower with Thymalin than with Tocilizumab. (Advances in gerontology = Uspekhi gerontologii, 2022)
In guinea pigs immunized with bacterial antigen, the study found that allergic reactions to thymalin were possible. (Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1993)

See every safety result on the Scientific page

Doses studied (10 shown)

The doses that these studies used. They are not recommendations.

Dose as reported	Class	Species	Route	Duration	Design	Source
5 ml, 4-6 injections per treatment course	Human	human	Not reported	Not reported	Trial in people without random groups · n = 35	Dovnar 1989
100 micrograms per mouse	Animal	mouse	Subcutaneous	Single application at the day of infection	Study in live animals	Hermánek 1989
1.2 mg/kg	Animal	rat	Not reported	Not reported	Study in live animals	Platonov 2004
0.66 mg/kg	Animal	Mice	Injection	Not reported	Study in live animals	Potapov 1991
0.2 mlg/mice	Animal	mouse	intraperitoneally	Not reported	Study in live animals	Melekhin 1989
1 mg/kg/day	Animal	guinea pig	intramuscular	5 days	Study in live animals	Grintsevich 1984
1000 micrograms/mouse	Animal	mouse	i.p.	Not reported	Study in live animals	Gavrilenko 1982
2 mg	Animal	cat	Not reported	5 days	Study in live animals	Kuznik 1981
5 ng/ml	Lab	rat	Not reported	Not reported	Study on tissue taken from a body	Chalisova 1999
1000 and 100 micrograms/ml	Lab	Not reported	Not reported	Not reported	Test-tube study without cells	Pastorova 1989

From the community

How people use it

What people report online. It comes from forums and guides, not from studies.

Community-reported. Not tested in trials.

The wiki reports community use. The manufacturer reports a separate label regimen. Neither source establishes community efficacy or safety.

Reported routines and cautions

What people use it for

Community immune and aging useS1

Reported regimens

Regimens that community sources report for Thymalin. Community-reported, not tested in trials.
Context	Route	Amount	How often	How long	Agreement	Sources
Community immune and aging use	intramuscular injection	5 to 10 mg per dose	once daily	5 to 10 days, repeated 2 to 4 times per year	Single secondary wiki source. Original user reports and extract identity remain unverified.	S1

Community sources

S1Thymalin community protocols (opens in a new tab)www.peptideprotocolwiki.com

plus 1 seller page (not linked)

Gaps

The wiki does not verify direct community reports or product equivalence. Affiliate payments remain unconfirmed. Full manufacturer instruction access requires authorisation. Adult label duration remains unset because the public dose sentence also covers children.

Questions and more

Ask a question about Thymalin

The answer links to every study it uses.

What does the evidence say about Thymalin?Is Thymalin tested in people?Compare with Thymosin alpha-1 Compare with Vasoactive intestinal peptide (VIP, aviptadil)

Sources

Database: PepBank data for Thymalin (data version 308560)
Regulator: FDA status record
Regulator: EMA status record
Regulator: WADA status record
Community: community sources (forums and guides), as summarized in the PepBank community file

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

PepBank is a research reference. Talk to a doctor before you use any peptide.

Ask your AI about Thymalin

Curo is a peptide shop. PepBank and Curo have the same owner. See the Curo catalog (opens in a new tab).

Thymalin

Approved in RussiaNot banned in sport

Also known as Thymaline, Timalin, Тималин

What it is

Mixture

Approval

Approved in Russia only (registered as Thymalin / Тималин)

In sport

Not listed as banned by WADA

Studies

161 studies with results. 85 of them gave Thymalin, with 242 results.
76 in people146 in animals20 in lab cells

Best study in people

Non-randomized trial with 116 people (1989)

Clinical trials

None registered

Community use

Community immune and aging use

Dose as reported

Class

Species

Route

Duration

Design

Source

5 ml, 4-6 injections per treatment course

Human

human

Not reported

Trial in people without random groups · n = 35

Dovnar 1989

100 micrograms per mouse

Animal

mouse

Subcutaneous

Single application at the day of infection

Study in live animals

Hermánek 1989

1.2 mg/kg

Animal

rat

Not reported

Study in live animals

Platonov 2004

0.66 mg/kg

Animal

Mice

Injection

Not reported

Study in live animals

Potapov 1991

0.2 mlg/mice

Animal

mouse

intraperitoneally

Not reported

Study in live animals

Melekhin 1989

1 mg/kg/day

Animal

guinea pig

intramuscular

5 days

Study in live animals

Grintsevich 1984

1000 micrograms/mouse

Animal

mouse

i.p.

Not reported

Study in live animals

Gavrilenko 1982

2 mg

Animal

cat

Not reported

5 days

Study in live animals

Kuznik 1981

5 ng/ml

Lab

rat

Not reported

Study on tissue taken from a body

Chalisova 1999

1000 and 100 micrograms/ml

Lab

Not reported

Test-tube study without cells

Pastorova 1989

Context

Route

Amount

How often

How long

Agreement

Sources

Community immune and aging use

intramuscular injection

5 to 10 mg per dose

once daily

5 to 10 days, repeated 2 to 4 times per year

Single secondary wiki source. Original user reports and extract identity remain unverified.

Thymalin

Thymalin at a glance

What is Thymalin?

Thymalin structure and chemistry

What Thymalin studies show

Immune system and inflammation

Blood and clotting

Survival and serious illness

Infections

Cancer

Daily life and fitness

Key Thymalin studies

Thymalin clinical trials

Is Thymalin approved?

Thymalin side effects and safety

How people use it

What people use it for

Reported regimens

Community sources

Ask a question about Thymalin

Related peptides

Sources

Thymalin

Thymalin at a glance

What is Thymalin?

Thymalin structure and chemistry

What Thymalin studies show

Immune system and inflammation

Blood and clotting

Survival and serious illness

Infections

Cancer

Daily life and fitness

Key Thymalin studies

Thymalin clinical trials

Is Thymalin approved?

Thymalin side effects and safety

How people use it

What people use it for

Reported regimens

Community sources

Ask a question about Thymalin

Related peptides

Sources