In ulcerative colitis with inflammatory-destructive mucosal changes, thymalin was less effective than corticosteroids.
In plain wordsIn patients with ulcerative colitis and inflammatory-destructive changes, thymalin was less effective than corticosteroids.
- Peptide
- Thymalin
- Outcome
- DecreaseEfficacy in inflammatory-destructive mucosal changes
- Study
n = 50
- Comparator
- Corticosteroids
- Outcome group
- Gastrointestinal protection · Gastrointestinal
- Studied dose
- Dose not stated
Source sentences
Corticosteroids were more effective in inflammatory-destructive changes in the mucosa of the large intestine while in mild inflammation with prevalence of ulcerative-reparative processes, immunomodulators (thymalin) are preferred.
1 context sentence(design, population, supporting numbers)
A comparative study of the clinico-immunological efficacy of steroid hormones and thymus drugs in 50 patients with unspecific ulcerative colitis of different activity grades revealed that their efficacy was not similar at different phases of the disease and depended on the activity of the inflammatory process.