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Study · Animal study (in vivo) · mouse · 1991

2 results

[The effect of thymalin on the count of large granular lymphocytes in the peripheral blood of mice with leukemia P388].

Potapov IuN, Khaleev DV, Krutova TV, Pashkova VS

Izvestiia Akademii nauk SSSR. Seriia biologicheskaia1 Jan 1991

PMID1856357 (opens in a new tab)PepBankPUB-01856357
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice with P388 leukemia, multiple thymaline injections maintained large granular lymphocyte counts at the control level.

    In plain wordsIn mice with leukemia, thymaline injections maintained large granular lymphocyte counts at the level of control animals.

    Peptide
    Thymalin
    Outcome
    No significant changeLarge granular lymphocyte count
    Study

    Micen: not reported in source

    P388 leukemia
    Comparator
    Control animals
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    0.66 mg/kg · InjectionAs given in this study (Mice).

    Source sentences

    Summary
    Multiple thymaline injections (0.66 mg/kg) maintain the numbers of the lymphocytes at the level of control animals but did not increase the life span of leukemia mice.
    1 context sentence
    Summary · context
    Effect of thymaline injections on peripheral blood natural killer cells in mice with p388 leukemia has been studied.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In mice with P388 leukemia, multiple thymaline injections did not increase lifespan.

    In plain wordsIn mice with leukemia, thymaline injections did not increase lifespan.

    Peptide
    Thymalin
    Outcome
    No significant changeLifespan
    Study

    Micen: not reported in source

    P388 leukemia
    Outcome group
    Mortality · Whole body
    Studied dose
    0.66 mg/kg · InjectionAs given in this study (Mice).

    Source sentences

    Summary
    Multiple thymaline injections (0.66 mg/kg) maintain the numbers of the lymphocytes at the level of control animals but did not increase the life span of leukemia mice.
    1 context sentence
    Summary · context
    Effect of thymaline injections on peripheral blood natural killer cells in mice with p388 leukemia has been studied.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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