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Study · Animal study (in vivo) · mouse · 1982

4 results

[Effect of thymalin on the cyclic nucleotide system in the mouse spleen].

Gavrilenko IS, Khavinson VKh, Morozov VG, Ivnitskiĭ IuIu

Biulleten' eksperimental'noi biologii i meditsiny1 Apr 1982

PMID6282361 (opens in a new tab)DOI10.1007/bf00830542 (opens in a new tab)PepBankPUB-06282361
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In mice, thymalin produced two-phasic changes in spleen cAMP content.

    In plain wordsIn mice, thymalin changed spleen cAMP levels in two phases.

    Peptide
    Thymalin
    Outcome
    MixedSpleen cAMP content
    Study

    mousen: not reported in source

    mouse spleen
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    1000 micrograms/mouse · i.p.As given in this study (mouse).

    Source sentences

    Summary
    The preparation produced two-phasic changes in the content of cAMP and cGMP, as well as in the activity of cAMP phosphodiesterase.
    1 context sentence
    Summary · context
    The effect of the thymus preparation thymalin (1000 micrograms/mouse, i.p.) on the system of cyclic nucleotides in the spleen has been studied.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In mice, thymalin produced two-phasic changes in spleen cGMP content.

    In plain wordsIn mice, thymalin changed spleen cGMP levels in two phases.

    Peptide
    Thymalin
    Outcome
    MixedSpleen cGMP content
    Study

    mousen: not reported in source

    mouse spleen
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    1000 micrograms/mouse · i.p.As given in this study (mouse).

    Source sentences

    Summary
    The preparation produced two-phasic changes in the content of cAMP and cGMP, as well as in the activity of cAMP phosphodiesterase.
    1 context sentence
    Summary · context
    The effect of the thymus preparation thymalin (1000 micrograms/mouse, i.p.) on the system of cyclic nucleotides in the spleen has been studied.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In mice, thymalin produced two-phasic changes in spleen cAMP phosphodiesterase activity.

    In plain wordsIn mice, thymalin changed spleen cAMP phosphodiesterase activity in two phases.

    Peptide
    Thymalin
    Outcome
    MixedcAMP phosphodiesterase activity
    Study

    mousen: not reported in source

    mouse spleen
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    1000 micrograms/mouse · i.p.As given in this study (mouse).

    Source sentences

    Summary
    The preparation produced two-phasic changes in the content of cAMP and cGMP, as well as in the activity of cAMP phosphodiesterase.
    1 context sentence
    Summary · context
    The effect of the thymus preparation thymalin (1000 micrograms/mouse, i.p.) on the system of cyclic nucleotides in the spleen has been studied.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In mice treated with thymalin, spleen cAMP changes followed changes in phosphodiesterase activity.

    In plain wordsIn mice treated with thymalin, spleen cAMP changes followed changes in phosphodiesterase activity.

    Peptide
    Thymalin
    Outcome
    Not applicableRelationship of cAMP changes to phosphodiesterase activity
    Study

    mousen: not reported in source

    mouse spleen
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    1000 micrograms/mouse · i.p.As given in this study (mouse).

    Source sentences

    Summary
    The changes in the spleen cAMP content are consequent on those in the activity of phosphodiesterase.
    1 context sentence
    Summary · context
    The effect of the thymus preparation thymalin (1000 micrograms/mouse, i.p.) on the system of cyclic nucleotides in the spleen has been studied.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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