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Study · Other design · 1993

8 results

[A cytomorphological basis for the correction of radiation-induced immunodeficiencies and hematopoietic depression using thymus and bone marrow peptides].

Khmel'nitskiĭ OK, Grintsevich II, Kotov VA, Seryĭ SV

Arkhiv patologii1 Mar 1993

PMID7980063 (opens in a new tab)PepBankPUB-07980063
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalOther designEfficacy outcome

    In radiation injury studies with unresolved human and animal results, thymalin compensated for immune disturbances.

    In plain wordsIn mixed human and animal studies of radiation injury, thymalin compensated for immune disturbances.

    Peptide
    Thymalin
    Outcome
    Not applicableImmune disturbances
    Study

    n: not reported in source

    Radiation-induced immunodeficiency and hematopoietic depression
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymalin was able to compensate for immune disturbances and reduce manifestations of asthenia.
    1 context sentence
    Summary · context
    The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied.
  2. 02AnimalOther designEfficacy outcome

    In radiation injury studies with unresolved human and animal results, thymalin reduced manifestations of asthenia.

    In plain wordsIn mixed human and animal studies of radiation injury, thymalin reduced weakness.

    Peptide
    Thymalin
    Outcome
    DecreaseAsthenia manifestations
    Study

    n: not reported in source

    Radiation-induced immunodeficiency and hematopoietic depression
    Outcome group
    Exercise and physical function · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymalin was able to compensate for immune disturbances and reduce manifestations of asthenia.
    1 context sentence
    Summary · context
    The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied.

Studies that did not test the peptide alone6

In this study, the peptide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking the peptide.

  1. 03AnimalNot a test of Thymalin aloneOther designEfficacy outcome

    In radiation injury studies with unresolved human and animal results, pooled marrow and thymus preparations including thymalin promoted thymus recovery.

    In plain wordsIn mixed human and animal studies, pooled marrow and thymus preparations including thymalin promoted thymus recovery.

    Peptide
    Thymalin
    Outcome
    Not applicableThymus damage recovery
    Study

    n: not reported in source

    Radiation-induced immunodeficiency and hematopoietic depression
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Administration of the bone marrow and thymus recovery of damage to the thymus, bone marrow, spleen and lymph nodes, improved the function of circulating neutrophilic granulocytes.
    1 context sentence
    Summary · context
    The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  2. 04AnimalNot a test of Thymalin aloneOther designEfficacy outcome

    In radiation injury studies with unresolved human and animal results, pooled preparations including thymalin promoted bone marrow recovery.

    In plain wordsIn mixed human and animal studies, pooled preparations including thymalin promoted bone marrow recovery.

    Peptide
    Thymalin
    Outcome
    Not applicableBone marrow damage recovery
    Study

    n: not reported in source

    Radiation-induced immunodeficiency and hematopoietic depression
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Administration of the bone marrow and thymus recovery of damage to the thymus, bone marrow, spleen and lymph nodes, improved the function of circulating neutrophilic granulocytes.
    1 context sentence
    Summary · context
    The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  3. 05AnimalNot a test of Thymalin aloneOther designEfficacy outcome

    In radiation injury studies with unresolved human and animal results, pooled preparations including thymalin promoted spleen recovery.

    In plain wordsIn mixed human and animal studies, pooled preparations including thymalin promoted spleen recovery.

    Peptide
    Thymalin
    Outcome
    Not applicableSpleen damage recovery
    Study

    n: not reported in source

    Radiation-induced immunodeficiency and hematopoietic depression
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Administration of the bone marrow and thymus recovery of damage to the thymus, bone marrow, spleen and lymph nodes, improved the function of circulating neutrophilic granulocytes.
    1 context sentence
    Summary · context
    The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  4. 06AnimalNot a test of Thymalin aloneOther designEfficacy outcome

    In radiation injury studies with unresolved human and animal results, pooled preparations including thymalin promoted lymph node recovery.

    In plain wordsIn mixed human and animal studies, pooled preparations including thymalin promoted lymph node recovery.

    Peptide
    Thymalin
    Outcome
    Not applicableLymph node damage recovery
    Study

    n: not reported in source

    Radiation-induced immunodeficiency and hematopoietic depression
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Administration of the bone marrow and thymus recovery of damage to the thymus, bone marrow, spleen and lymph nodes, improved the function of circulating neutrophilic granulocytes.
    1 context sentence
    Summary · context
    The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  5. 07AnimalNot a test of Thymalin aloneOther designEfficacy outcome

    In radiation injury studies with unresolved human and animal results, pooled preparations including thymalin improved circulating neutrophilic granulocyte function.

    In plain wordsIn mixed human and animal studies, pooled preparations including thymalin improved circulating neutrophil function.

    Peptide
    Thymalin
    Outcome
    IncreaseCirculating neutrophilic granulocyte function
    Study

    n: not reported in source

    Radiation-induced immunodeficiency and hematopoietic depression
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Administration of the bone marrow and thymus recovery of damage to the thymus, bone marrow, spleen and lymph nodes, improved the function of circulating neutrophilic granulocytes.
    1 context sentence
    Summary · context
    The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  6. 08AnimalNot a test of Thymogen (oglufanide) aloneOther designEfficacy outcome

    In pooled clinical and animal experiments, thymus and bone marrow preparations, including thymogen, improved circulating neutrophilic granulocyte function.

    In plain wordsIn pooled patient and animal experiments, preparations including thymogen improved circulating neutrophil function.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseCirculating neutrophilic granulocyte function
    Study

    n: not reported in source

    Radiation-induced immunodeficiency and hematopoietic depression
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Administration of the bone marrow and thymus recovery of damage to the thymus, bone marrow, spleen and lymph nodes, improved the function of circulating neutrophilic granulocytes.
    1 context sentence
    Summary · context
    The correction of radiation-induced immunodeficiency and hematopoiesis depression in clinical setting (100 patients) and in experiments (160 animals) by peptide preparations of the thymus and bone marrow (thymalin, hemalin, thymogemine and synthetic thymalin analog thymogen) has been studied.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 12:50 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    14 Oct 2026, 05:02 UTC

    Study results updated

  3. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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