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Pramlintide (Symlin) studies: 145 papers with results

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  1. Ex vivo human placental transfer of the peptides pramlintide and exenatide (synthetic exendin-4).

    Hiles RA · Human & experimental toxicology · 2003

    Ex vivo tissue · 1 result

  2. Pramlintide Antagonizes Beta Amyloid (Aβ)- and Human Amylin-Induced Depression of Hippocampal Long-Term Potentiation.

    Kimura R · Molecular neurobiology · 2017

    Ex vivo tissue · mouse · 5 results

  3. Islet amyloid polypeptide toxicity and membrane interactions.

    Cao P · Proceedings of the National Academy of Sciences of the United States of America · 2013

    In vitro (cells) · 2 results

  4. Activity of pramlintide, rat and human amylin but not Aβ1-42 at human amylin receptors.

    Gingell JJ · Endocrinology · 2014

    In vitro (cells) · 4 results

  5. Pramlintide regulation of extracellular matrix (ECM) and apoptosis through mitochondrial-dependent pathways in human nucleus pulposus cells.

    Wu X · International journal of immunopathology and pharmacology · 2018

    In vitro (cells) · 12 results

  6. Pramlintide, an antidiabetic, is antineoplastic in colorectal cancer and synergizes with conventional chemotherapy.

    Al-Keilani MS · Clinical pharmacology : advances and applications · 2018

    In vitro (cells) · 5 results

  7. Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide.

    Nuñez-Diaz C · Molecular brain · 2023

    In vitro (cells) · 1 result

  8. Pramlintide: An Amylin Analogue Protects Endothelial Cells against Oxidative Stress through Regulating Oxidative Markers and NF-κb Expression.

    Safaeian L · International journal of preventive medicine · 2022

    In vitro (cells) · 7 results

  9. Development of the novel amylin and calcitonin receptor activators by peptide mutagenesis.

    Lee S · Archives of biochemistry and biophysics · 2024

    In vitro (cells) · 2 results

  10. The effect of pramlintide, an antidiabetic amylin analogue, on angiogenesis-related markers in vitro.

    Safaeian L · Research in pharmaceutical sciences · 2020

    In vitro (cells) · 6 results

  11. Amylin receptor agonism enhances the effects of liraglutide in protecting against the acute metabolic side effects of olanzapine.

    Medak KD · iScience · 2024

    Other design · 8 results

  12. A co-formulation of pramlintide and insulin A21G (ADO09) improves postprandial glucose and short-term control of mean glucose, time in range, and body weight versus insulin aspart in adults with type 1 diabetes.

    Andersen G · Diabetes, obesity & metabolism · 2023

    Not a test of Pramlintide (Symlin) alone · 11 results

  13. Enhanced weight loss following coadministration of pramlintide with sibutramine or phentermine in a multicenter trial.

    Aronne LJ · Obesity (Silver Spring, Md.) · 2010

    Not a test of Pramlintide (Symlin) alone · 10 results

  14. A Phase 2 Evaluation of a Novel Co-Formulation of Pramlintide and Regular Insulin to Improve Postprandial Glycemic Control in Adults with Type 1 Diabetes (T1D)

    Edelman S · Journal of the Endocrine Society · 2021

    Not a test of Pramlintide (Symlin) alone · 10 results

  15. ADO09, a co-formulation of the amylin analogue pramlintide and the insulin analogue A21G, lowers postprandial blood glucose versus insulin lispro in type 1 diabetes.

    Andersen G · Diabetes, obesity & metabolism · 2021

    Not a test of Pramlintide (Symlin) alone · 7 results

  16. Combined GLP-1 Receptor Agonist and Amylin Analogue Pharmacotherapy to Treat Obesity Comorbid With Type 1 Diabetes.

    Wong G · JCEM case reports · 2023

    Not a test of Pramlintide (Symlin) alone · 10 results

  17. ADO09, a co-formulation of pramlintide and insulin A21G, lowers body weight versus insulin lispro in type 1 diabetes.

    Andersen G · Diabetes, obesity & metabolism · 2024

    Not a test of Pramlintide (Symlin) alone · 6 results

  18. A Pilot Outpatient Assessment of a Fully Closed-Loop Insulin and Pramlintide System.

    Odabassian M · Journal of diabetes science and technology · 2025

    Not a test of Pramlintide (Symlin) alone · 6 results

  19. Properties of pramlintide and insulin upon mixing.

    Weyer C · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2005

    Not a test of Pramlintide (Symlin) alone · 5 results

  20. Simple meal announcements and pramlintide delivery versus carbohydrate counting in type 1 diabetes with automated fast-acting insulin aspart delivery: a randomised crossover trial in Montreal, Canada.

    Cohen E · The Lancet. Digital health · 2024

    Not a test of Pramlintide (Symlin) alone · 5 results

  21. Fully Automated Artificial Pancreas for Adults With Type 1 Diabetes Using Multiple Hormones: Exploratory Experiments.

    Majdpour D · Canadian journal of diabetes · 2021

    Not a test of Pramlintide (Symlin) alone · 5 results

  22. Ultra-Fast Insulin-Pramlintide Co-Formulation for Improved Glucose Management in Diabetic Rats.

    Maikawa CL · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021

    Not a test of Pramlintide (Symlin) alone · 5 results

  23. Involvement of amylin B-H2S-connexin 43 signaling pathway in vascular dysfunction and enhanced ischemia-reperfusion-induced myocardial injury in diabetic rats.

    Liu X · Bioscience reports · 2020

    Not a test of Pramlintide (Symlin) alone · 5 results

  24. Systemic Pharmacokinetic Principles of Therapeutic Peptides.

    Nordell P · Clinical pharmacokinetics · 2026

    Not a test of Pramlintide (Symlin) alone · 22 results

  25. A co-formulation of supramolecularly stabilized insulin and pramlintide enhances mealtime glucagon suppression in diabetic pigs.

    Maikawa CL · Nature biomedical engineering · 2020

    Not a test of Pramlintide (Symlin) alone · 4 results

  26. A fully artificial pancreas versus a hybrid artificial pancreas for type 1 diabetes: a single-centre, open-label, randomised controlled, crossover, non-inferiority trial.

    Tsoukas MA · The Lancet. Digital health · 2021

    Not a test of Pramlintide (Symlin) alone · 4 results

  27. Zn(II) binding to pramlintide results in a structural kink, fibril formation and antifungal activity.

    Dudek D · Scientific reports · 2022

    Not a test of Pramlintide (Symlin) alone · 4 results

  28. A temperature-responsive dual-hormone foam nanoengine improves rectal absorptivity of insulin-pramlintide for diabetes treatment.

    Feng S · Science advances · 2024

    Not a test of Pramlintide (Symlin) alone · 4 results

  29. Comparison of the post-meal glucose response to different insulin bolus waveforms in insulin pump- and pre-meal pramlintide-treated type 1 diabetes patients.

    King AB · Diabetes technology & therapeutics · 2010

    Not a test of Pramlintide (Symlin) alone · 4 results

  30. In silico design of optimal ratio for co-administration of pramlintide and insulin in type 1 diabetes.

    Micheletto F · Diabetes technology & therapeutics · 2013

    Not a test of Pramlintide (Symlin) alone · 3 results

  31. Reducing postprandial hyperglycemia with adjuvant premeal pramlintide and postmeal insulin in children with type 1 diabetes mellitus.

    Hassan K · Pediatric diabetes · 2009

    Not a test of Pramlintide (Symlin) alone · 3 results

  32. Effect of proline mutations on the monomer conformations of amylin.

    Chiu CC · Biophysical journal · 2013

    Not a test of Pramlintide (Symlin) alone · 2 results

  33. Rationally designed, nontoxic, nonamyloidogenic analogues of human islet amyloid polypeptide with improved solubility.

    Wang H · Biochemistry · 2014

    Not a test of Pramlintide (Symlin) alone · 2 results

  34. Fusion Outcomes of GLP-1 Agonist Therapy in Multilevel Cervical Spinal Fusion: A Propensity-Matched Analysis.

    Vatsia SK · Clinical spine surgery · 2025

    Not a test of Pramlintide (Symlin) alone · 8 results

  35. Complete characterization of the mutation landscape reveals the effect on amylin stability and amyloidogenicity.

    Smaoui MR · Proteins · 2015

    Not a test of Pramlintide (Symlin) alone · 2 results

  36. INTERACTIONS OF METFORMIN AND OTHER MEDICATIONS IN REDUCING THE ODDS OF AGE-RELATED MACULAR DEGENERATION IN A COHORT OF PATIENTS WITH DIABETES.

    Shaw L · Retina (Philadelphia, Pa.) · 2024

    Not a test of Pramlintide (Symlin) alone · 2 results

  37. A model of glucose-insulin-pramlintide pharmacokinetics and pharmacodynamics in type I diabetes.

    Ramkissoon CM · Journal of diabetes science and technology · 2014

    Not a test of Pramlintide (Symlin) alone · 2 results

  38. A model of subcutaneous pramlintide pharmacokinetics and its effect on gastric emptying: Proof-of-concept based on populational data.

    Furió-Novejarque C · Computer methods and programs in biomedicine · 2024

    Not a test of Pramlintide (Symlin) alone · 2 results

  39. Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies.

    Roth JD · Proceedings of the National Academy of Sciences of the United States of America · 2008

    Not a test of Pramlintide (Symlin) alone · 1 result

  40. A closed-loop synthetic gene circuit for the treatment of diet-induced obesity in mice.

    Rössger K · Nature communications · 2013

    Not a test of Pramlintide (Symlin) alone · 1 result

  41. Analysis of the ability of pramlintide to inhibit amyloid formation by human islet amyloid polypeptide reveals a balance between optimal recognition and reduced amyloidogenicity.

    Wang H · Biochemistry · 2015

    Not a test of Pramlintide (Symlin) alone · 1 result

  42. Structural effects driven by rare point mutations in amylin hormone, the type II diabetes-associated peptide.

    Mendes WS · Biochimica et biophysica acta. General subjects · 2021

    Not a test of Pramlintide (Symlin) alone · 1 result

  43. Synergistic long-range effects of mutations underlie aggregation propensities of amylin analogues.

    Alves NA · Journal of molecular modeling · 2019

    Not a test of Pramlintide (Symlin) alone · 1 result

  44. Case Series of Nizon-Isidor Syndrome by Heterozygous Variants in MED12L With Further Evidence of Mitotic Instability in One Case With Diploid-Triploid Mosaicism.

    Stewart R · American journal of medical genetics. Part A · 2026

    Not a test of Pramlintide (Symlin) alone · 2 results

  45. In silico evaluation of pramlintide dosing algorithms in artificial pancreas systems.

    Pons Torres B · Computers in biology and medicine · 2025

    Not a test of Pramlintide (Symlin) alone · 1 result

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