In obese mice on a high-fat diet, implanted cells engineered to express pramlintide reduced food consumption, blood lipid levels and body weight.
In plain wordsIn mice, implanted cells engineered to express pramlintide reduced food consumption, blood lipid levels and body weight.
- Peptide
- Pramlintide (Symlin)
- Outcome
- DecreaseFood consumption, blood lipids and body weight
- Study
mousen: not reported in source
Diet-induced obesity with implanted engineered cells- Outcome group
- Body weight · Metabolic and weight
Source sentences
Mice with diet-induced obesity in which microencapsulated cells engineered for LSR-driven expression of pramlintide are implanted show significant reduction in food consumption, blood lipid levels and body weight when put on a high-fat diet.
In this study, Pramlintide (Symlin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Pramlintide (Symlin).