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Pramlintide (Symlin) studies: 145 papers with results

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  1. Psychometric properties of an instrument for assessing treatment satisfaction associated with pramlintide use.

    Rubin RR · The Diabetes educator · 2009

    Randomized controlled trial · 9 results

  2. Impact of Disease Duration on the Effects of Pramlintide in Type 1 Diabetes: A Post Hoc Analysis of Three Clinical Trials.

    Herrmann K · Advances in therapy · 2016

    Randomized controlled trial · 9 results

  3. Pramlintide for post-bariatric hypoglycaemia.

    Sheehan A · Diabetes, obesity & metabolism · 2022

    Non-randomized trial · 6 results

  4. Minimal reduction in insulin dosage with pramlintide therapy when pretreatment near-normal glycemia is established and square-wave meal bolus is used.

    King AB · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2009

    Non-randomized trial · 8 results

  5. Adjunctive therapy with pramlintide lowers HbA1c without concomitant weight gain and increased risk of severe hypoglycemia in patients with type 1 diabetes approaching glycemic targets.

    Ratner R · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2005

    Non-randomized trial · 3 results

  6. Effect of adjunctive pramlintide treatment on treatment satisfaction in patients with type 1 diabetes.

    Marrero DG · Diabetes care · 2007

    Non-randomized trial · 5 results

  7. Pramlintide as an adjunct to insulin in patients with type 2 diabetes in a clinical practice setting reduced A1C, postprandial glucose excursions, and weight.

    Karl D · Diabetes technology & therapeutics · 2007

    Non-randomized trial · 7 results

  8. Study reanalysis using a mechanism-based pharmacokinetic/pharmacodynamic model of pramlintide in subjects with type 1 diabetes.

    Fang J · The AAPS journal · 2013

    Non-randomized trial · 4 results

  9. Pharmacokinetics of an oral drug (acetaminophen) administered at various times relative to subcutaneous injection of pramlintide in subjects with type 2 diabetes.

    Kellmeyer TA · Journal of clinical pharmacology · 2007

    Non-randomized trial · 5 results

  10. The effect of pramlintide (amylin analogue) treatment on bone metabolism and bone density in patients with type 1 diabetes mellitus.

    Borm AK · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 1999

    Non-randomized trial · 5 results

  11. Impact of pramlintide on glucose fluctuations and postprandial glucose, glucagon, and triglyceride excursions among patients with type 1 diabetes intensively treated with insulin pumps.

    Levetan C · Diabetes care · 2003

    Non-randomized trial · 12 results

  12. The amylin analog pramlintide improves glycemic control and reduces postprandial glucagon concentrations in patients with type 1 diabetes mellitus.

    Nyholm B · Metabolism: clinical and experimental · 1999

    Non-randomized trial · 11 results

  13. Importance of changes in gastric emptying for postprandial plasma glucose fluxes in healthy humans.

    Woerle HJ · American journal of physiology. Endocrinology and metabolism · 2008

    Non-randomized trial · 11 results

  14. Effects of the amylin analogue pramlintide on hepatic glucagon responses and intermediary metabolism in Type 1 diabetic subjects.

    Orskov L · Diabetic medicine : a journal of the British Diabetic Association · 1999

    Non-randomized trial · 5 results

  15. Continuous subcutaneous pramlintide infusion therapy in patients with type 1 diabetes: observations from a pilot study.

    Huffman DM · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2009

    Non-randomized trial · 9 results

  16. Mitigating Meal-Related Glycemic Excursions in an Insulin-Sparing Manner During Closed-Loop Insulin Delivery: The Beneficial Effects of Adjunctive Pramlintide and Liraglutide.

    Sherr JL · Diabetes care · 2016

    Non-randomized trial · 8 results

  17. Reduction of postprandial hyperglycemia in subjects with IDDM by intravenous infusion of AC137, a human amylin analogue.

    Kolterman OG · Diabetes care · 1995

    Non-randomized trial · 5 results

  18. Effect of pramlintide on prandial glycemic excursions during closed-loop control in adolescents and young adults with type 1 diabetes.

    Weinzimer SA · Diabetes care · 2012

    Non-randomized trial · 3 results

  19. Pramlintide but Not Liraglutide Suppresses Meal-Stimulated Glucagon Responses in Type 1 Diabetes.

    Galderisi A · The Journal of clinical endocrinology and metabolism · 2018

    Non-randomized trial · 5 results

  20. Alleviating carbohydrate counting with a FiASP-plus-pramlintide closed-loop delivery system (artificial pancreas): Feasibility and pilot studies.

    Tsoukas MA · Diabetes, obesity & metabolism · 2021

    Non-randomized trial · 6 results

  21. Effects of pramlintide, an analog of human amylin, on plasma glucose profiles in patients with IDDM: results of a multicenter trial.

    Thompson RG · Diabetes · 1997

    Non-randomized trial · 11 results

  22. Pharmacokinetics and pharmacodynamics of AC137 (25,28,29 tripro-amylin, human) after intravenous bolus and infusion doses in patients with insulin-dependent diabetes.

    Colburn WA · Journal of clinical pharmacology · 1996

    Non-randomized trial · 7 results

  23. Effects of delayed gastric emptying on postprandial glucose kinetics, insulin sensitivity, and β-cell function.

    Hinshaw L · American journal of physiology. Endocrinology and metabolism · 2014

    Non-randomized trial · 6 results

  24. An amylin analog used as a challenge test for Alzheimer's disease.

    Zhu H · Alzheimer's & dementia (New York, N. Y.) · 2017

    Non-randomized trial · 5 results

  25. Assessing treatment satisfaction in patients treated with pramlintide as an adjunct to insulin therapy.

    Rubin RR · Current medical research and opinion · 2007

    Non-randomized trial · 7 results

  26. Effects of pramlintide in patients with type 2 diabetes mellitus: an analysis using daily insulin dose tertiles.

    Herrmann K · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2014

    Non-randomized trial · 7 results

  27. Pramlintide: The Effects of a Single Drug Injection on Blood Phosphatidylcholine Profile for Alzheimer's Disease.

    Tao Q · Journal of Alzheimer's disease : JAD · 2018

    Non-randomized trial · 8 results

  28. Pramlintide reduces the risks associated with glucose variability in type 1 diabetes.

    Kovatchev BP · Diabetes technology & therapeutics · 2008

    Observational study · 5 results

  29. A novel analytical method for assessing glucose variability: using CGMS in type 1 diabetes mellitus.

    McCall AL · Diabetes technology & therapeutics · 2006

    Observational study · 4 results

  30. Off-label use of exenatide for the management of insulin-resistant type 1 diabetes mellitus in an obese patient with human immunodeficiency virus infection.

    Sheffield CA · Pharmacotherapy · 2007

    Case report or series · 1 result

  31. REDUCTION IN SUBCUTANEOUS INSULIN REQUIREMENTS IN TETRAPLEGIC TYPE 1 DIABETIC WITH CERVICAL SPINAL CORD INJURY FOLLOWING PRAMLINTIDE TREATMENT.

    Salamone F · AACE clinical case reports · 2020

    Case report or series · 1 result

  32. IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo.

    Venkatanarayan A · Nature · 2015

    Animal study (in vivo) · mouse · 1 result

  33. Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition.

    Adler BL · Neurobiology of aging · 2014

    Animal study (in vivo) · mouse · 7 results

  34. Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease.

    Zhu H · Molecular psychiatry · 2015

    Animal study (in vivo) · mouse · 5 results

  35. Neuroprotective Effects of the Amylin Analog, Pramlintide, on Alzheimer's Disease Are Associated with Oxidative Stress Regulation Mechanisms.

    Patrick S · Journal of Alzheimer's disease : JAD · 2019

    Animal study (in vivo) · mouse · 6 results

  36. Effect of amylin on memory and central insulin resistance in a rat model of Alzheimer's disease.

    Nassar SZ · Archives of physiology and biochemistry · 2020

    Animal study (in vivo) · rat · 5 results

  37. [D-Leu-4]-OB3, a synthetic peptide amide with leptin-like activity, augments the effects of orally delivered exenatide and pramlintide acetate on energy balance and glycemic control in insulin-resistant male C57BLK/6-m db/db mice.

    Leinung MC · Regulatory peptides · 2012

    Animal study (in vivo) · mouse · 20 results

  38. Nephrectomy decreases amylin and pramlintide clearance in rats.

    Vine W · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 1998

    Animal study (in vivo) · rat · 1 result

  39. From the pancreas to the amygdala: New brain area critical for ingestive and motivated behavior control exerted by amylin.

    Byun S · iScience · 2025

    Animal study (in vivo) · rat · 2 results

  40. Pramlintide: A Novel Therapeutic Approach for Osteosarcoma through Metabolic Reprogramming.

    Yang Y · Cancers · 2022

    Animal study (in vivo) · mouse · 8 results

  41. Injectable Biodegradable Silica Depot: Two Months of Sustained Release of the Blood Glucose Lowering Peptide, Pramlintide.

    Tyagi P · Pharmaceutics · 2022

    Animal study (in vivo) · rat · 3 results

  42. Human IAPP is a contributor to painful diabetic peripheral neuropathy.

    Albariqi MM · The Journal of clinical investigation · 2023

    Animal study (in vivo) · mouse · 2 results

  43. Neuroprotective Mechanisms of Amylin Receptor Activation, Not Antagonism, in the APP/PS1 Mouse Model of Alzheimer's Disease.

    Corrigan RR · Journal of Alzheimer's disease : JAD · 2023

    Animal study (in vivo) · mouse · 5 results

  44. Design, synthesis and preclinical evaluation of bio-conjugated amylinomimetic peptides as long-acting amylin receptor agonists.

    Patch RJ · European journal of medicinal chemistry · 2022

    Animal study (in vivo) · mouse · 1 result

  45. Effects of pramlintide on energy intake and food preference in rats given a choice diet.

    Kern KA · Physiology & behavior · 2021

    Animal study (in vivo) · rat · 10 results

  46. Chronic pramlintide decreases feeding via a reduction in meal size in male rats.

    Kern KA · Peptides · 2024

    Animal study (in vivo) · rat · 5 results

  47. Expression, purification, and biological activity of the recombinant pramlintide precursor.

    Hu H · Applied microbiology and biotechnology · 2014

    Animal study (in vivo) · 2 results

  48. Intranasal administration of dextran-pramlintide polyelectrolyte complex-coated nanoemulsions improves cognitive impairments in a mouse model of Alzheimer's disease.

    Zuglianello C · International journal of biological macromolecules · 2024

    Animal study (in vivo) · mouse · 9 results

  49. Central pramlintide administration potently suppresses operant responding for sucrose and locomotor activity in male rats.

    Kern KA · Physiology & behavior · 2025

    Animal study (in vivo) · rat · 8 results

  50. Intranasal pramlintide matches intraperitoneal effects on food intake and gastric emptying in mice.

    Almeida MS · Endocrine · 2025

    Animal study (in vivo) · mouse · 14 results

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