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Exenatide (exendin-4) studies: 530 papers with results

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  1. Effects of exenatide on microvascular reactivity in patients with type 2 diabetes and coronary artery disease: A randomized controlled study.

    Östlund Papadogeorgos N · Microcirculation (New York, N.Y. : 1994) · 2021

    Randomized controlled trial · 4 results

  2. Exenatide once weekly slows gastric emptying of solids and liquids in healthy, overweight people at steady-state concentrations.

    Jones KL · Diabetes, obesity & metabolism · 2020

    Randomized controlled trial · 8 results

  3. Effect of exenatide on the pharmacokinetics of a combination oral contraceptive in healthy women: an open-label, randomised, crossover trial.

    Kothare PA · BMC clinical pharmacology · 2012

    Randomized controlled trial · 12 results

  4. Exenatide reduces urinary transforming growth factor-β1 and type IV collagen excretion in patients with type 2 diabetes and microalbuminuria.

    Zhang H · Kidney & blood pressure research · 2012

    Randomized controlled trial · 4 results

  5. One-year treatment with exenatide vs. insulin glargine: effects on postprandial glycemia, lipid profiles, and oxidative stress.

    Bunck MC · Atherosclerosis · 2010

    Randomized controlled trial · 7 results

  6. Effect of exenatide on 24-hour blood glucose profile compared with placebo in patients with type 2 diabetes: a randomized, double-blind, two-arm, parallel-group, placebo-controlled, 2-week study.

    Schwartz SL · Clinical therapeutics · 2008

    Randomized controlled trial · 8 results

  7. The effects of add-on exenatide to insulin on glycemic variability and hypoglycemia in patients with type 1 diabetes mellitus.

    Jiang LL · Journal of endocrinological investigation · 2018

    Randomized controlled trial · 16 results

  8. The effects of exenatide and insulin glargine treatments on bone turnover markers and bone mineral density in postmenopausal patients with type 2 diabetes mellitus.

    Akyay OZ · Medicine · 2023

    Randomized controlled trial · 8 results

  9. Improvement of postprandial endothelial function after a single dose of exenatide in individuals with impaired glucose tolerance and recent-onset type 2 diabetes.

    Koska J · Diabetes care · 2010

    Randomized controlled trial · 2 results

  10. Exenatide for diagnosing endogenous hyperinsulinemic hypoglycemia: a randomized placebo-controlled, double-blind, cross-over proof-of-principle study.

    Hepprich M · European journal of endocrinology · 2025

    Randomized controlled trial · 7 results

  11. [Effects of GLP-1 Agonist Exenatide on Cardiac Diastolic Function and Vascular Endothelial Function in Diabetic Patients].

    Wang XH · Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2015

    Randomized controlled trial · 11 results

  12. Comparison of the effects of exenatide and insulin glargine on right and left ventricular myocardial deformation as shown by 2D-speckle-tracking echocardiograms.

    Akyay OZ · Nigerian journal of clinical practice · 2022

    Randomized controlled trial · 8 results

  13. The use of exenatide in severely burned pediatric patients.

    Mecott GA · Critical care (London, England) · 2010

    Randomized controlled trial · 4 results

  14. Exenatide Increases IL-1RA Concentration and Induces Nrf-2‒Keap-1‒Regulated Antioxidant Enzymes: Relevance to β-Cell Function.

    Dandona P · The Journal of clinical endocrinology and metabolism · 2018

    Randomized controlled trial · 7 results

  15. Exenatide pharmacokinetics in healthy Chinese subjects.

    Zhao X · International journal of clinical pharmacology and therapeutics · 2008

    Randomized controlled trial · 13 results

  16. Effect of exenatide on inflammatory and oxidative stress markers in patients with type 2 diabetes mellitus.

    Wu JD · Diabetes technology & therapeutics · 2011

    Randomized controlled trial · 11 results

  17. Exenatide improves diastolic function and attenuates arterial stiffness but does not alter exercise capacity in individuals with type 2 diabetes.

    Scalzo RL · Journal of diabetes and its complications · 2017

    Randomized controlled trial · 5 results

  18. Exenatide decreases hepatic fibroblast growth factor 21 resistance in non-alcoholic fatty liver disease in a mouse model of obesity and in a randomised controlled trial.

    Samson SL · Diabetologia · 2011

    Randomized controlled trial · 11 results

  19. The Glucagon-Like Peptide 1 Receptor Agonist Exenatide Inhibits Small Intestinal Motility, Flow, Transit, and Absorption of Glucose in Healthy Subjects and Patients With Type 2 Diabetes: A Randomized Controlled Trial.

    Thazhath SS · Diabetes · 2016

    Randomized controlled trial · 7 results

  20. Exenatide in obesity with accelerated gastric emptying: a randomized, pharmacodynamics study.

    Acosta A · Physiological reports · 2015

    Randomized controlled trial · 7 results

  21. Preventive effects of exenatide on endothelial dysfunction induced by ischemia-reperfusion injury via KATP channels.

    Ha SJ · Arteriosclerosis, thrombosis, and vascular biology · 2012

    Randomized controlled trial · 5 results

  22. Effect of exenatide, insulin and pioglitazone on bone metabolism in patients with newly diagnosed type 2 diabetes.

    Li R · Acta diabetologica · 2015

    Randomized controlled trial · 6 results

  23. Study of postprandial lipaemia in type 2 diabetes mellitus: exenatide versus liraglutide.

    Voukali M · Journal of diabetes research · 2014

    Randomized controlled trial · 5 results

  24. Effect of administration time of exenatide on satiety responses, blood glucose, and adverse events in healthy volunteers.

    Pinelli NR · Journal of clinical pharmacology · 2011

    Randomized controlled trial · 11 results

  25. Exenatide: effect of injection time on postprandial glucose in patients with Type 2 diabetes.

    Linnebjerg H · Diabetic medicine : a journal of the British Diabetic Association · 2006

    Randomized controlled trial · 8 results

  26. Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes.

    Linnebjerg H · Regulatory peptides · 2008

    Randomized controlled trial · 8 results

  27. Exenatide, a glucagon-like peptide-1 receptor agonist, acutely inhibits intestinal lipoprotein production in healthy humans.

    Xiao C · Arteriosclerosis, thrombosis, and vascular biology · 2012

    Randomized controlled trial · 4 results

  28. Exenatide Regulates Cerebral Glucose Metabolism in Brain Areas Associated With Glucose Homeostasis and Reward System.

    Daniele G · Diabetes · 2015

    Randomized controlled trial · 6 results

  29. Acute Exenatide Therapy Attenuates Postprandial Vasodilation in Humans with Prediabetes: A Randomized Controlled Trial.

    Hamidi V · Metabolic syndrome and related disorders · 2020

    Randomized controlled trial · 11 results

  30. Exenatide exerts a potent antiinflammatory effect.

    Chaudhuri A · The Journal of clinical endocrinology and metabolism · 2012

    Randomized controlled trial · 24 results

  31. Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia.

    Degn KB · Diabetes · 2004

    Randomized controlled trial · 11 results

  32. Effects of exenatide on cardiac function, perfusion, and energetics in type 2 diabetic patients with cardiomyopathy: a randomized controlled trial against insulin glargine.

    Chen WJY · Cardiovascular diabetology · 2017

    Randomized controlled trial · 4 results

  33. Acute effects of the glucagon-like peptide-1 receptor agonist, exenatide, on blood pressure and heart rate responses to intraduodenal glucose infusion in type 2 diabetes.

    Thazhath SS · Diabetes & vascular disease research · 2017

    Randomized controlled trial · 5 results

  34. Exenatide alters myocardial glucose transport and uptake depending on insulin resistance and increases myocardial blood flow in patients with type 2 diabetes.

    Gejl M · The Journal of clinical endocrinology and metabolism · 2012

    Randomized controlled trial · 6 results

  35. The role of adjunctive exenatide therapy in pediatric type 1 diabetes.

    Raman VS · Diabetes care · 2010

    Randomized controlled trial · 3 results

  36. Safety, tolerability, pharmacokinetics, and pharmacodynamics of exenatide once weekly in Japanese patients with type 2 diabetes.

    Iwamoto K · Endocrine journal · 2009

    Randomized controlled trial · 13 results

  37. Acute effects of glucagon-like peptide-1, GLP-19-36 amide, and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers.

    Bremholm L · Physiological reports · 2017

    Randomized controlled trial · 5 results

  38. A randomized, open-label, crossover study examining the effect of injection site on bioavailability of exenatide (synthetic exendin-4).

    Calara F · Clinical therapeutics · 2005

    Randomized controlled trial · 17 results

  39. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes.

    DeFronzo RA · Diabetes care · 2005

    Randomized controlled trial · 9 results

  40. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea.

    Kendall DM · Diabetes care · 2005

    Randomized controlled trial · 9 results

  41. Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus.

    Kolterman OG · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2005

    Randomized controlled trial · 8 results

  42. A Pilot Study of Exenatide Actions in Alzheimer's Disease.

    Mullins RJ · Current Alzheimer research · 2019

    Randomized controlled trial · 7 results

  43. Further improvement in postprandial glucose control with addition of exenatide or sitagliptin to combination therapy with insulin glargine and metformin: a proof-of-concept study.

    Arnolds S · Diabetes care · 2010

    Randomized controlled trial · 12 results

  44. Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.

    Bunck MC · Diabetes care · 2010

    Randomized controlled trial · 6 results

  45. Effects of exenatide plus rosiglitazone on beta-cell function and insulin sensitivity in subjects with type 2 diabetes on metformin.

    DeFronzo RA · Diabetes care · 2010

    Randomized controlled trial · 11 results

  46. Safety and Efficacy of Exenatide Once Weekly Plus Dapagliflozin Once Daily Versus Exenatide or Dapagliflozin Alone in Patients With Type 2 Diabetes Inadequately Controlled With Metformin Monotherapy: 52-Week Results of the DURATION-8 Randomized Controlled Trial.

    Jabbour SA · Diabetes care · 2018

    Randomized controlled trial · 12 results

  47. Exenatide, Dapagliflozin, or Phentermine/Topiramate Differentially Affect Metabolic Profiles in Polycystic Ovary Syndrome.

    Elkind-Hirsch KE · The Journal of clinical endocrinology and metabolism · 2021

    Randomized controlled trial · 4 results

  48. Efficacy and safety of biphasic insulin aspart 70/30 versus exenatide in subjects with type 2 diabetes failing to achieve glycemic control with metformin and a sulfonylurea.

    Bergenstal R · Current medical research and opinion · 2009

    Randomized controlled trial · 9 results

  49. Exenatide-induced reduction in energy intake is associated with increase in hypothalamic connectivity.

    Schlögl H · Diabetes care · 2013

    Randomized controlled trial · 2 results

  50. Impact of acute hyperglycemia on myocardial infarct size, area at risk, and salvage in patients with STEMI and the association with exenatide treatment: results from a randomized study.

    Lønborg J · Diabetes · 2014

    Randomized controlled trial · 2 results

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