Semaglutide studies: 1,194 papers with results
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- Clinical Trial: Semaglutide Versus Placebo in NIT-Assessed MASH-A Multicenter Randomised Placebo-Controlled Trial (SAMARA).
Ajmera V · Alimentary pharmacology & therapeutics · 2026
Randomized controlled trial · 9 results
- A randomized study investigating the effect of omeprazole on the pharmacokinetics of oral semaglutide.
Bækdal TA · Expert opinion on drug metabolism & toxicology · 2018
Randomized controlled trial · 4 results
- Oral Semaglutide for Alcohol Use Disorder: A Randomized Clinical Trial.
Schacht JP · The American journal of psychiatry · 2026
Randomized controlled trial · 8 results
- Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes (PIONEER 9): a 52-week, phase 2/3a, randomised, controlled trial.
Yamada Y · The lancet. Diabetes & endocrinology · 2020
Randomized controlled trial · 13 results
- Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial.
Hendershot CS · JAMA psychiatry · 2025
Randomized controlled trial · 8 results
- Semaglutide promotes bone marrow-derived progenitor cell flux towards an anti-inflammatory and pro-regenerative profile in high-risk patients: the SEMA-VR CardioLink-15 trial.
Park B · European heart journal · 2026
Randomized controlled trial · 6 results
- A Randomized Trial Investigating the Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Semaglutide Once-Weekly in Healthy Male Japanese and Caucasian Subjects.
Ikushima I · Advances in therapy · 2018
Randomized controlled trial · 10 results
- Comparison of Effects of Injectable Semaglutide and Dulaglutide on Oxidative Stress and Glucose Variability in Patients with Type 2 Diabetes Mellitus: A Prospective Preliminary Study.
Omachi T · Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
Randomized controlled trial · 10 results
- Pharmacokinetics, Safety and Tolerability of Once-Weekly Subcutaneous Semaglutide in Healthy Chinese Subjects: A Double-Blind, Phase 1, Randomized Controlled Trial.
Shi A · Advances in therapy · 2021
Randomized controlled trial · 5 results
- Effect of once-weekly semaglutide on the counterregulatory response to hypoglycaemia in people with type 2 diabetes: A randomized, placebo-controlled, double-blind, crossover trial.
Korsatko S · Diabetes, obesity & metabolism · 2018
Randomized controlled trial · 8 results
- A phase 1, randomized, double-blind, placebo-controlled trial investigating the pharmacokinetics, pharmacodynamics, safety and tolerability of oral semaglutide in healthy Chinese subjects.
Xie P · Diabetes, obesity & metabolism · 2024
Randomized controlled trial · 10 results
- Efficacy and safety of semaglutide versus placebo for people with schizophrenia on clozapine with obesity (COaST): a phase 2, multi-centre, participant and investigator- blinded, randomised controlled trial in Australia.
Siskind D · The lancet. Psychiatry · 2025
Randomized controlled trial · 6 results
- Relationship Between Oral Semaglutide Tablet Erosion and Pharmacokinetics: A Pharmacoscintigraphic Study.
Baekdal TA · Clinical pharmacology in drug development · 2021
Randomized controlled trial · 7 results
- Subcutaneous weekly semaglutide with automated insulin delivery in type 1 diabetes: a double-blind, randomized, crossover trial.
Pasqua MR · Nature medicine · 2025
Randomized controlled trial · 6 results
- Once-Weekly Semaglutide in Adults With Daily Cigarette Use: A Randomized Clinical Trial.
Hendershot CS · JAMA network open · 2026
Randomized controlled trial · 7 results
- Evaluation of the Safety, Efficacy and Pharmacokinetics of BGM0504 in Chinese Adults With Type 2 Diabetes: A Multicentre, Randomised, Controlled and Double-Blind Phase II Trial.
Jin P · Diabetes, obesity & metabolism · 2026
Randomized controlled trial · 1 result
- Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes.
Dahl K · Diabetes, obesity & metabolism · 2021
Randomized controlled trial · 14 results
- A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis.
Newsome PN · The New England journal of medicine · 2021
Randomized controlled trial · 10 results
- Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.
Frías JP · The New England journal of medicine · 2021
Randomized controlled trial · 19 results
- Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial.
Rubino DM · JAMA · 2022
Randomized controlled trial · 14 results
- Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial.
O'Neil PM · Lancet (London, England) · 2018
Randomized controlled trial · 10 results
- Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial.
Rosenstock J · JAMA · 2019
Randomized controlled trial · 10 results
- A Phase 2, Randomized, Dose-Finding Study of the Novel Once-Weekly Human GLP-1 Analog, Semaglutide, Compared With Placebo and Open-Label Liraglutide in Patients With Type 2 Diabetes.
Nauck MA · Diabetes care · 2016
Randomized controlled trial · 14 results
- A 26-Week Randomized Controlled Trial of Semaglutide Once Daily Versus Liraglutide and Placebo in Patients With Type 2 Diabetes Suboptimally Controlled on Diet and Exercise With or Without Metformin.
Lingvay I · Diabetes care · 2018
Randomized controlled trial · 7 results
- Bimagrumab plus semaglutide alone or in combination for the treatment of obesity: a randomized phase 2 trial.
Heymsfield SB · Nature medicine · 2026
Randomized controlled trial · 6 results
- Artificial intelligence scoring of liver biopsies in a phase II trial of semaglutide in nonalcoholic steatohepatitis.
Ratziu V · Hepatology (Baltimore, Md.) · 2024
Randomized controlled trial · 4 results
- Effects of Aerobic Training and Semaglutide Treatment on Pancreatic β-Cell Secretory Function in Patients With Type 2 Diabetes.
Ingersen A · The Journal of clinical endocrinology and metabolism · 2023
Randomized controlled trial · 5 results
- Efficacy and safety of oral semaglutide monotherapy vs placebo in a predominantly Chinese population with type 2 diabetes (PIONEER 11): a double-blind, Phase IIIa, randomised trial.
Wang W · Diabetologia · 2024
Randomized controlled trial · 12 results
- Separate and combined effects of empagliflozin and semaglutide on vascular function: A 32-week randomized trial.
Vernstrøm L · Diabetes, obesity & metabolism · 2024
Randomized controlled trial · 6 results
- Assessment of Cardiovascular Risk With Glucagon-Like Peptide 1 Receptor Agonists in Patients With Type 2 Diabetes Using an Alternative Measure to the Hazard Ratio.
Kaneko M · The Annals of pharmacotherapy · 2018
Randomized controlled trial · 4 results
- Weekly and Biweekly Treatment With Bofanglutide Versus Semaglutide in Chinese Patients With Type 2 Diabetes : A Phase 2b Randomized Clinical Trial.
Liu M · Annals of internal medicine · 2026
Randomized controlled trial · 3 results
- Semaglutide and diuretic use in obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF-DM trials.
Shah SJ · European heart journal · 2024
Randomized controlled trial · 9 results
- Benefit of Semaglutide in Symptomatic Peripheral Artery Disease by Baseline Type 2 Diabetes Characteristics: Insights From STRIDE, a Randomized, Placebo-Controlled, Double-Blind Trial.
Rasouli N · Diabetes care · 2025
Randomized controlled trial · 7 results
- Improved health-related quality of life with semaglutide in people with non-alcoholic steatohepatitis: A randomised trial.
Romero-Gómez M · Alimentary pharmacology & therapeutics · 2023
Randomized controlled trial · 8 results
- Long-term efficacy and safety of oral semaglutide and the effect of switching from sitagliptin to oral semaglutide in patients with type 2 diabetes: a 52-week, randomized, open-label extension of the PIONEER 7 trial.
Buse JB · BMJ open diabetes research & care · 2020
Randomized controlled trial · 7 results
- Effect of Semaglutide on Insulin Sensitivity and Cardiometabolic Risk Factors in Adolescents With Obesity: The STEP TEENS Study.
Arslanian S · Diabetes care · 2026
Randomized controlled trial · 10 results
- Effects of semaglutide and empagliflozin on oxygenation, vascular autoregulation, and central thickness of the retina in people with type 2 diabetes: A prespecified secondary analysis of a randomised clinical trial.
Gullaksen S · Journal of diabetes and its complications · 2023
Randomized controlled trial · 5 results
- The impact of semaglutide on liver fat assessed by serial cardiac CT scans in patients with type 2 diabetes: Results from STOP trial.
Golub IS · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
Randomized controlled trial · 2 results
- Semaglutide and Effort-Based Decision-Making in Major Depressive Disorder: A Randomized Clinical Trial.
Gill H · JAMA psychiatry · 2026
Randomized controlled trial · 4 results
- Efficacy and safety of oral semaglutide in Japanese patients with type 2 diabetes: A subgroup analysis by baseline variables in the PIONEER 9 and PIONEER 10 trials.
Yabe D · Journal of diabetes investigation · 2022
Randomized controlled trial · 5 results
- Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension.
Wilding JPH · Diabetes, obesity & metabolism · 2022
Randomized controlled trial · 4 results
- Semaglutide slows epigenetic aging in a randomized trial of HIV-associated lipohypertrophy.
Corley MJ · Nature communications · 2026
Randomized controlled trial · 7 results
- Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients with non-alcoholic steatohepatitis: A randomised, open-label phase II trial.
Alkhouri N · Journal of hepatology · 2022
Randomized controlled trial · 6 results
- Semaglutide, reduction in glycated haemoglobin and the risk of diabetic retinopathy.
Vilsbøll T · Diabetes, obesity & metabolism · 2018
Randomized controlled trial · 2 results
- Reducing BMI below the obesity threshold in adolescents treated with once-weekly subcutaneous semaglutide 2.4 mg.
Kelly AS · Obesity (Silver Spring, Md.) · 2023
Randomized controlled trial · 3 results
- Improved treatment satisfaction in patients with type 2 diabetes treated with once-weekly semaglutide in the SUSTAIN trials.
Jendle J · Diabetes, obesity & metabolism · 2019
Randomized controlled trial · 6 results
- Impact of BMI and comorbidities on efficacy of once-weekly semaglutide: Post hoc analyses of the STEP 1 randomized trial.
McGowan BM · Obesity (Silver Spring, Md.) · 2023
Randomized controlled trial · 4 results
- Greater improvement in insulin sensitivity per unit weight loss associated with tirzepatide versus semaglutide: An exploratory analysis.
Mather KJ · Diabetes, obesity & metabolism · 2025
Randomized controlled trial · 4 results
- Efficacy and safety of oral semaglutide in Japanese patients with type 2 diabetes: A post hoc subgroup analysis of the PIONEER 1, 3, 4 and 8 trials.
Araki E · Diabetes, obesity & metabolism · 2021
Randomized controlled trial · 10 results
- Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial.
Ryan DH · Nature medicine · 2024
Randomized controlled trial · 12 results