Semaglutide studies: 1,194 papers with results
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- Long-term kidney outcomes of semaglutide in obesity and cardiovascular disease in the SELECT trial.
Colhoun HM · Nature medicine · 2024
Randomized controlled trial · 3 results
- Effect of Semaglutide on Regression and Progression of Glycemia in People With Overweight or Obesity but Without Diabetes in the SELECT Trial.
Kahn SE · Diabetes care · 2024
Randomized controlled trial · 7 results
- Semaglutide and Cardiovascular Outcomes by Baseline HbA1c and Change in HbA1c in People With Overweight or Obesity but Without Diabetes in SELECT.
Lingvay I · Diabetes care · 2024
Randomized controlled trial · 3 results
- The Effect of Semaglutide on Mortality and COVID-19-Related Deaths: An Analysis From the SELECT Trial.
Scirica BM · Journal of the American College of Cardiology · 2024
Randomized controlled trial · 9 results
- Impact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial.
Mann JFE · Diabetes care · 2026
Randomized controlled trial · 5 results
- Effects of once-weekly subcutaneous semaglutide on kidney function and safety in patients with type 2 diabetes: a post-hoc analysis of the SUSTAIN 1-7 randomised controlled trials.
Mann JFE · The lancet. Diabetes & endocrinology · 2020
Randomized controlled trial · 19 results
- Proportion of participants with type 2 diabetes achieving a metabolic composite endpoint with once-weekly semaglutide treatment versus comparators: Post hoc pooled analysis from SUSTAIN 1-5, 7-10 and SUSTAIN China.
Ji L · Diabetes, obesity & metabolism · 2024
Randomized controlled trial · 3 results
- Effects of Semaglutide on Stroke Subtypes in Type 2 Diabetes: Post Hoc Analysis of the Randomized SUSTAIN 6 and PIONEER 6.
Strain WD · Stroke · 2022
Randomized controlled trial · 7 results
- Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial.
Deanfield J · Lancet (London, England) · 2024
Randomized controlled trial · 10 results
- Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials.
Kosiborod MN · Lancet (London, England) · 2024
Randomized controlled trial · 4 results
- Gastrointestinal tolerability of once-weekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss.
Wharton S · Diabetes, obesity & metabolism · 2022
Randomized controlled trial · 10 results
- Psychiatric Safety of Semaglutide for Weight Management in People Without Known Major Psychopathology: Post Hoc Analysis of the STEP 1, 2, 3, and 5 Trials.
Wadden TA · JAMA internal medicine · 2024
Randomized controlled trial · 5 results
- The effect of glucagon-like peptide-1 receptor agonists liraglutide and semaglutide on cardiovascular and renal outcomes across baseline blood pressure categories: Analysis of the LEADER and SUSTAIN 6 trials.
Leiter LA · Diabetes, obesity & metabolism · 2020
Randomized controlled trial · 4 results
- Impact of microvascular disease on cardiovascular outcomes in type 2 diabetes: Results from the LEADER and SUSTAIN 6 clinical trials.
Verma S · Diabetes, obesity & metabolism · 2020
Randomized controlled trial · 4 results
- Oral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes: A Secondary Analysis of the SOUL Randomized Clinical Trial.
Pop-Busui R · JAMA internal medicine · 2026
Randomized controlled trial · 7 results
- Tirzepatide Improved Markers of Islet Cell Function and Insulin Sensitivity in People With T2D (SURPASS-2).
Frias JP · The Journal of clinical endocrinology and metabolism · 2024
Randomized controlled trial · 10 results
- Effect of semaglutide 2.4 mg once weekly on 10-year type 2 diabetes risk in adults with overweight or obesity.
Wilkinson L · Obesity (Silver Spring, Md.) · 2023
Randomized controlled trial · 5 results
- Efficacy and safety of oral semaglutide in Chinese participants with type 2 diabetes: Subgroup analyses by baseline characteristics in the PIONEER 11 and 12 randomised controlled trials.
Ji L · Diabetes, obesity & metabolism · 2025
Randomized controlled trial · 4 results
- Semaglutide and NT-proBNP in Obesity-Related HFpEF: Insights From the STEP-HFpEF Program.
Petrie MC · Journal of the American College of Cardiology · 2024
Randomized controlled trial · 6 results
- Semaglutide and NYHA Functional Class in Obesity-Related Heart Failure With Preserved Ejection Fraction: The STEP-HFpEF Program.
Schou M · Journal of the American College of Cardiology · 2024
Randomized controlled trial · 8 results
- Impact of baseline characteristics on the efficacy of once-weekly subcutaneous semaglutide among participants with type 2 diabetes: A post hoc analysis of SUSTAIN China.
Ji L · Diabetes, obesity & metabolism · 2024
Randomized controlled trial · 6 results
- Clinical characteristics affecting weight loss in an East Asian population receiving semaglutide: A STEP 6 subgroup analysis.
Kadowaki T · Obesity research & clinical practice · 2024
Randomized controlled trial · 5 results
- Similar weight loss with semaglutide regardless of diabetes and cardiometabolic risk parameters in individuals with metabolic dysfunction-associated steatotic liver disease: Post hoc analysis of three randomised controlled trials.
Armstrong MJ · Diabetes, obesity & metabolism · 2025
Randomized controlled trial · 10 results
- Exploration of Multiple Non-Invasive Tests for Assessing Response to Treatment in a Semaglutide Phase 2b Trial in Patients with MASH.
Nitze LM · Alimentary pharmacology & therapeutics · 2026
Randomized controlled trial · 4 results
- Safety and Pharmacokinetics of Single and Multiple Ascending Doses of the Novel Oral Human GLP-1 Analogue, Oral Semaglutide, in Healthy Subjects and Subjects with Type 2 Diabetes.
Granhall C · Clinical pharmacokinetics · 2019
Randomized controlled trial · 6 results
- Tirzepatide compared with semaglutide in obesity disease: a subpopulation analysis applying Japan Society for the Study of Obesity criteria in the global SURMOUNT-5 trial.
Kitamoto T · Current medical research and opinion · 2026
Randomized controlled trial · 7 results
- Two-year effect of semaglutide 2.4 mg on control of eating in adults with overweight/obesity: STEP 5.
Wharton S · Obesity (Silver Spring, Md.) · 2023
Randomized controlled trial · 12 results
- Improved quality of life with semaglutide in schizophrenia: Secondary analyses from a randomized controlled trial.
Uhrenholt N · Schizophrenia research · 2026
Randomized controlled trial · 7 results
- Improvement of β-Cell Function After Switching From DPP-4 Inhibitors to Oral Semaglutide: SWITCH-SEMA2 Post Hoc Analysis.
Nomoto H · The Journal of clinical endocrinology and metabolism · 2025
Randomized controlled trial · 7 results
- Semaglutide Effects on Insulin Sensitivity and β-Cell Function in Patients With Schizophrenia, Prediabetes, and Obesity Treated With Second-Generation Antipsychotics: Findings From the HISTORI Trial, a 30-Week Randomized, Placebo-Controlled Trial With Semaglutide 1.0 mg Weekly.
Ganeshalingam AA · Diabetes care · 2026
Randomized controlled trial · 9 results
- Short- and long-term effects of semaglutide 2.4 mg on energy intake, appetite, and food reward: a 60-week, double-blind randomized controlled trial.
Tronieri JS · The American journal of clinical nutrition · 2026
Randomized controlled trial · 9 results
- Effects of subcutaneous tirzepatide versus placebo or semaglutide on pancreatic islet function and insulin sensitivity in adults with type 2 diabetes: a multicentre, randomised, double-blind, parallel-arm, phase 1 clinical trial.
Heise T · The lancet. Diabetes & endocrinology · 2022
Randomized controlled trial · 12 results
- Oral semaglutide for weight loss and liver fibrosis in overweight and obesity: A randomized controlled trial.
Katrevula A · Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
Randomized controlled trial · 14 results
- Effect of Swallow Balloon Therapy with the Combination of Semaglutide Oral Formulation: a Randomised Double-Blind Single-Centre Study.
Mathur W · Obesity surgery · 2024
Randomized controlled trial · 10 results
- Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised controlled clinical trial.
McCrimmon RJ · Diabetologia · 2020
Randomized controlled trial · 5 results
- Effects of Semaglutide on Cognitive Function in People With HIV: A Randomized, Controlled Trial.
Atieh O · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
Randomized controlled trial · 7 results
- Effect of once-weekly subcutaneous semaglutide on arterial inflammation in people with type 2 diabetes and cardiovascular disease using PET-MRI: Primary results of a randomized, double-blind, placebo-controlled trial.
James S · American heart journal · 2025
Randomized controlled trial · 2 results
- Effects of Semaglutide on Body Composition and GFR: A Prespecified Analysis of the SMART Trial.
Heerspink HJL · Clinical journal of the American Society of Nephrology : CJASN · 2026
Randomized controlled trial · 7 results
- Effects of a 6-week subcutaneous infusion of native GIP alone or as add-on to semaglutide in people with type 2 diabetes: a single-centre, double-blind, parallel-group, randomised, placebo-controlled trial.
Helsted MM · The lancet. Diabetes & endocrinology · 2026
Randomized controlled trial · 4 results
- Effects of semaglutide, empagliflozin and their combination on renal diffusion-weighted MRI and total kidney volume in patients with type 2 diabetes: a post hoc analysis from a 32 week randomised trial.
Vernstrøm L · Diabetologia · 2024
Randomized controlled trial · 10 results
- Adjunctive Semaglutide in Patients Undergoing Intragastric Balloon for Weight Loss: 12-Month Prospective Comparative Study.
Barakat KE · Obesity surgery · 2025
Randomized controlled trial · 4 results
- Pharmacokinetic Properties of a Once-Weekly Fixed-Ratio Combination of Insulin Icodec and Semaglutide Compared with Separate Administration of Each Component in Individuals with Type 2 Diabetes Mellitus.
Westergaard L · Clinical drug investigation · 2024
Randomized controlled trial · 6 results
- Effect of Switching to Once-Weekly Semaglutide on Non-Alcoholic Fatty Liver Disease: The SWITCH-SEMA 1 Subanalysis.
Nomoto H · Pharmaceutics · 2023
Randomized controlled trial · 7 results
- Effects of once-weekly semaglutide on appetite, energy intake, control of eating, food preference and body weight in subjects with obesity.
Blundell J · Diabetes, obesity & metabolism · 2017
Randomized controlled trial · 13 results
- Semaglutide improves postprandial glucose and lipid metabolism, and delays first-hour gastric emptying in subjects with obesity.
Hjerpsted JB · Diabetes, obesity & metabolism · 2018
Randomized controlled trial · 11 results
- Semaglutide and Taste in Women With Obesity and Polycystic Ovary Syndrome: A Randomized Placebo-Controlled Study.
Jensterle M · The Journal of clinical endocrinology and metabolism · 2025
Randomized controlled trial · 4 results
- Changes to insulin requirements over time with semaglutide in adults with type 1 diabetes on insulin pump therapy: A post-hoc analysis of a double-blinded, randomised, crossover trial.
Pasqua MR · Diabetes, obesity & metabolism · 2026
Randomized controlled trial · 8 results
- Semaglutide reduces fat accumulation in the tongue: A randomized single-blind, pilot study.
Jensterle M · Diabetes research and clinical practice · 2021
Randomized controlled trial · 3 results
- Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism.
Gregorič N · Diabetes, obesity & metabolism · 2025
Randomized controlled trial · 7 results
- Semaglutide Use With Automated Insulin Delivery in Adults With Type 1 Diabetes: Qualitative Analyses and Patient-reported Outcomes From a Randomized Controlled Trial.
Pasqua MR · Canadian journal of diabetes · 2026
Randomized controlled trial · 8 results