SLU-PP-332 is a small molecule, not a peptide, that switches on estrogen-related receptors, and researchers call it an exercise mimetic. It is not approved and is banned in sport as an unapproved substance, and it has been studied only in cells and animals. PepBank shows 42 results on SLU-PP-332 from animal and lab studies. No study in people has reported results yet. Data as of 2026-10-30.
Also known as 332, SLU, SLU PP 332, SLUPP, SLUPP332, Sloop and 5 more
| What it is | Small molecule |
|---|---|
| Approval | Not approved for any use |
| In sport | Banned in sport (WADA S0) |
| Studies | 9 studies with results. 7 of them gave SLU-PP-332, with 42 results. 27 in animals15 in lab cells |
| Clinical trials | None registered |
| Community use | Fat loss and a leaner body composition (cutting phases); Endurance, cardio and training capacity ('exercise mimetic'); A mitochondrial-support stack with MOTS-c, L-carnitine or 5-amino-1MQ; Kidney and blood lab markers (one forum thread, anecdotal) |
Small molecule (not a peptide) that switches on all three estrogen-related receptors, ERR alpha, beta and gamma, most strongly alpha. Researchers call it an exercise mimetic. It has been studied only in cells and animals. No approval, no human trial and no FDA compounding listing were found.
Study results in PepBank
The key facts about the molecule. Long codes are in the closed section below.
InChIKeyRNZIMBFHRXYRLL-XDHOZWIPSA-N
SMILESC1=CC=C2C=C(C=CC2=C1)/C=N/NC(=O)C3=CC=C(C=C3)O
Results grouped by what the studies measured. Each card shows where its results come from.
In mice, SLU‑PP‑332 increased type IIa oxidative muscle fibers. ACS chemical biology, 2023
In mice with pressure overload-induced heart failure, SLU‑PP‑332 improved ejection fraction. Circulation, 2024
In mice with obesity and metabolic syndrome, SLU‑PP‑332 reduced fat accumulation. The Journal of pharmacology and experimental therapeutics, 2024
In mice, SLU‑PP‑332 reversed the increase in mitochondrial dysfunction associated with aging. The American journal of pathology, 2023
In mice with metabolic syndrome, SLU‑PP‑332 improved insulin sensitivity. The Journal of pharmacology and experimental therapeutics, 2024
In mice, SLU‑PP‑332 reversed the increase in inflammatory cytokines associated with aging. The American journal of pathology, 2023
Studies in people come first, then studies in animals and in the lab.
No approved medicine contains it.
No approved medicine contains it.
On the 2026 Prohibited List, section S0.
No. Not approved for any use. Preclinical research only. No clinical trial phase found. The FDA, the EMA and the other sources we use show no approval (as of 13 Oct 2026). Banned in sport (WADA S0).
Laws and labels change, so check the regulator for the current status.
PepBank has 1 safety result from studies of SLU-PP-332. None of them come from studies in people, so they do not show what happens in people.
What people report online. It comes from forums and guides, not from studies.
Community sources describe SLU-PP-332 as an 'exercise mimetic' that people mostly take by mouth in capsules or tablets, and less often by injection under the skin. Reported amounts run from a few hundred micrograms a day to 100 mg or more a day, and the sources disagree on which range makes sense. People report warmth, sweating, a faster heart rate and more hunger, and some report no effect.
| Context | Route | Amount | How often | How long | Agreement | Sources |
|---|---|---|---|---|---|---|
| Fat loss, endurance and training, low (microgram) range by mouth | oral (tablets or capsules)S1 and S8 describe capsules, some enteric coated. S5 and S4 describe tablets in 250 to 1,000 mcg sizes. | 200 to 4500 mcg per day | once daily, or split into 2 to 3 doses; S8 says doses are timed around training and cardio | reports run from about 2 weeks to 10 weeks; S5 plans 10 months a year with 1 to 2 week breaks; S8 gives 12 to 16 weeks on, then 4 to 8 weeks off | S4, S5 and S8 give amounts of 0.2 to 2 mg a day. S6 gives up to 4.5 mg a day (1,500 mcg three times a day). The sources differ on timing and cycle length. | S4S5S6S8 |
| Fat loss, endurance and training, high (milligram) range by mouth | oral (capsules or tablets)S1 says members fill their own enteric capsules from raw powder, or buy capsules or tablets. | 20 to 400 mg per day | daily, often split into 2 to 4 capsules; some members time doses away from training, others before it | 3 to 4 weeks in several posts; one S1 member reports 20 or more weeks | sources differ: most posts give 20 to 100 mg a day, but some give 150 mg to 400 mg a day. Posts do not agree on timing or cycle length. | S1S2S4S6S8 |
| Fat loss and training, injection under the skin | injection (subcutaneous in S1 and S7; S3 says 'injectable' and does not name the site)The compound does not dissolve in water. S1 reports mixing it in MCT oil. S3 reports cloudy mixes with bacteriostatic water. S7 reports a suspension. | 250 to 4500 mcg per dose or day, as each source states | S1 gives 'ED' (every day) for one member; other posts do not say | Not stated | single sources; amounts differ from 250 mcg to 4.5 mg | S1S3S7 |
| Fat loss, energy and training (trainer's blog; route not stated) | not stated | 100 to 300 mcg per dose | twice daily, one dose before fasted cardio and one about six hours later before training | 10 weeks | single source | S9 |
| Transdermal use (spray or DMSO solution) | transdermal (spray, or a DMSO solution)S3 repeats hearsay that DMSO is the carrier. S7 reports a spray. No amounts are given. | Not stated | Not stated | Not stated | sources are single posts | S3S7 |
Gaps
SLU-PP-332 has no approved product, so there is no label regimen. No human trial exists, so there is no studied human dose. Mouse amounts from the papers are not community practice and are left out of this file. No independent lab test of a gray-market product was found. The Eroids forum thread on SLU-PP-332 returned HTTP 403, so it was not used. Reddit cannot be fetched. Seller and clinic pages were not used for any line. Amounts for skin use are not given in any source read. One S1 list gives '1mg sublingual oral' for one member with no frequency or length of use, so it is not used. The two WADA lists are PDFs, so their text was read with pdftotext and not with the quote script.
The answer links to every study it uses.
AI wrote and checked these results. AI can make mistakes, so check important results against the source.
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In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated