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Brilacidin / Studies
Small molecule · 936.9 Da

Brilacidin studies and research data

PepBank has 17 brilacidin studies with results. 15 of them gave brilacidin, with 72 results, grouped by what the studies measured. In each group, results from studies in people come first. Data as of 2026-10-30.

Searches 72 results and 29 papers. Newer studies from Europe PMC

Results in people
0
0% of 72 results
Results in animals
8
11% of 72 results
Results in lab cells
64
89% of 72 results
From computer models
0
0% of 72 results
The molecule

Brilacidin identity

Identifiers, parent molecule, targets and development stage, from curated data.

Brilacidin is a synthetic non-peptide molecule modeled on host-defense peptides. Laboratory studies describe membrane effects and antimicrobial activity. These mechanisms do not establish clinical benefit.

Kind
Small molecule
Formula
C40H50F6N14O6
Identifiers
ChEMBLCHEMBL2219413 (opens in a new tab)PubChem CID25023695 (opens in a new tab)UNIII1679X069H (opens in a new tab)DrugBankDB12997 (opens in a new tab)CAS1224095-98-0KEGGD10414 (opens in a new tab)IUPHAR13807 (opens in a new tab)
Development
Phase 2Innovation PharmaceuticalsRegistry records establish completed phase 2 trials. PolyMedix sponsored the earlier PMX-30063 trial. Innovation Pharmaceuticals developed later programs. Planned phase 3 development does not establish a completed phase 3 trial or current recruitment. Source (opens in a new tab)

Targets

No molecular target is recorded.

Structure

Structure from the identity record.

2D structure

Draws the structure in your browser with RDKit (about 2.3 MB, loaded once).

SMILES fromPubChem CID 25023695(opens in a new tab)

C1CNC[C@@H]1OC2=C(C=C(C=C2NC(=O)C3=CC(=NC=N3)C(=O)NC4=CC(=CC(=C4O[C@@H]5CCNC5)NC(=O)CCCCN=C(N)N)C(F)(F)F)C(F)(F)F)NC(=O)CCCCN=C(N)N
Results by area

What the studies measured

People first in each area, then animals, then lab cells. Counts are exact and come from studies that gave the peptide.

Trials and papers
Status and safety
Data