Peptides / Sexual health and hormones
Natural fragment · 13 amino acids · 1,664.9 Da
alpha-Melanocyte-stimulating hormone (alpha-MSH)
Not approvedMay be banned in sport
PepBank shows no results on alpha-Melanocyte-stimulating hormone (alpha-MSH) from studies in people, animals, the lab or computer predictions. Data as of 2026-10-30.
Also known as alpha-MSH, α-MSH, Melanocyte-stimulating hormone alpha, alpha-Melanocyte-stimulating hormone, alpha-Melanotropin, Intermedine and 1 more
13 amino acids, from first to lastSYSMEHFRWGKPV
Evidence level: No study results yetPepBank has no study results for alpha-Melanocyte-stimulating hormone (alpha-MSH) yet.
Results in people
0
0% of 0 results
Results in animals
0
0% of 0 results
Results in lab cells
0
0% of 0 results
From computer models
0
0% of 0 results
Overview
alpha-Melanocyte-stimulating hormone (alpha-MSH) at a glance
| What it is | Natural fragment, 13 amino acids |
|---|---|
| Approval | Not approved for any use |
| In sport | Not named on the List; S0 may still apply (no approval anywhere) |
| Studies | No study results for alpha-Melanocyte-stimulating hormone (alpha-MSH) yet |
| Clinical trials | None registered |
The science
What is alpha-Melanocyte-stimulating hormone (alpha-MSH)?
Natural 13-residue pituitary hormone cut from POMC; activates melanocortin receptors MC1R, MC3R, MC4R and MC5R. Parent of KPV.
13
Amino acids in one chain
alpha-Melanocyte-stimulating hormone (alpha-MSH) structure and chemistry
The key facts about the molecule. Long codes are in the closed section below.
Sequence, 13 amino acidsFrom the first amino acid to the last
S1YSM−E5HF+RWG10+KPV
Darker means more water-repelling+ and − show charge in the bodyOutlined: changed amino acid
Structure
alpha-Melanocyte-stimulating hormone (alpha-MSH) is a natural fragment of 13 amino acids, with no ring, 2 changed amino acids.
Formula
C77H109N21O19S
Molecular weight
1,664.9 g/mol
CAS number
581-05-5
Targets
Melanocyte-stimulating hormone receptor (gene MC1R): agonistEvidence: UniProt function annotation; GSRS TARGET->AGONIST relationshipMelanocortin receptor 3 (gene MC3R): agonistEvidence: UniProt function annotation; cryo-EM complex PDB 8W8WMelanocortin receptor 4 (gene MC4R): agonistEvidence: UniProt function annotation; cryo-EM complex PDB 7F53
Development
Highest phase: phase 1.
Identifiers
Full sequence, SMILES and InChIKey
Three-letter sequenceAc-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
InChIKeyWHNFPRLDDSXQCL-UAZQEYIDSA-N
SMILESCC(C)[C@@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CNC=N5)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)[C@H](CC6=CC=C(C=C6)O)NC(=O)[C@H](CO)NC(=O)C
The evidence
What alpha-Melanocyte-stimulating hormone (alpha-MSH) studies show
Results grouped by what the studies measured. Each card shows where its results come from.
No study results yetPepBank has no study results for alpha-Melanocyte-stimulating hormone (alpha-MSH) yet.
Key alpha-Melanocyte-stimulating hormone (alpha-MSH) studies
No study of alpha-Melanocyte-stimulating hormone (alpha-MSH) has results in PepBank yet.
alpha-Melanocyte-stimulating hormone (alpha-MSH) clinical trials
ClinicalTrials.gov lists no trial of alpha-Melanocyte-stimulating hormone (alpha-MSH). A trial under another name may exist.
Status and safety
Is alpha-Melanocyte-stimulating hormone (alpha-MSH) approved?
FDA
United States
Not approvedNo approved medicine contains it.
EMA
European Union
Not approvedNo approved medicine contains it.
WADA
Sport
May be bannedNot named on the List. Section S0 covers substances with no approval.
No. Not approved for any use. Its most advanced trial is in phase 1. The FDA, the EMA and the other sources we use show no approval (as of 8 Oct 2026). Not named on the List; S0 may still apply (no approval anywhere).
Laws and labels change, so check the regulator for the current status.
alpha-Melanocyte-stimulating hormone (alpha-MSH) side effects and safety
PepBank has no safety result from studies of alpha-Melanocyte-stimulating hormone (alpha-MSH) yet. That does not mean alpha-Melanocyte-stimulating hormone (alpha-MSH) is safe.
Questions and more
Ask a question about alpha-Melanocyte-stimulating hormone (alpha-MSH)
The answer links to every study it uses.
Sources
- Database: PepBank data for alpha-Melanocyte-stimulating hormone (alpha-MSH) (data version 308560)
- Regulator: FDA status record
- Regulator: EMA status record
- Regulator: WADA status record
AI wrote and checked these results. AI can make mistakes, so check important results against the source.
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