Palmitoyl tetrapeptide-7 is a cosmetic peptide used in skin care and in the Matrixyl 3000 blend, not an approved drug. On its own, it has been tested only in lab skin cells, on collagen after UV exposure and on cell safety. PepBank shows 2 results on palmitoyl tetrapeptide-7 from animal and lab studies. No study in people has reported results yet. Data as of 2026-10-30.
Also known as CytoPep, N-Palmitoyl-Rigin, N-Palmitoylrigin, Pal-GQPR, Pal-Gly-Gln-Pro-Arg, Palmitoyl Tetrapeptide-3 and 3 more
| What it is | Modified form, 4 amino acids |
|---|---|
| Approval | Regulatory status not recorded |
| In sport | Status unknown |
| Studies | 5 studies with results. 1 of them gave palmitoyl tetrapeptide-7, with 2 results. 2 in lab cells |
| Clinical trials | None registered |
| Community use | Skin conditioning in cosmetic products |
A palmitoylated GQPR peptide used in skin-conditioning cosmetics.
Amino acids in one chain
The key facts about the molecule. Long codes are in the closed section below.
Three-letter sequenceGly-Gln-Pro-Arg
InChIKeyIHRKJQSLKLYWBQ-QKDODKLFSA-N
SMILESCCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O
Results grouped by what the studies measured. Each card shows where its results come from.
In cells, palmitoyl tetrapeptide-7 significantly increased type III collagen levels after UV exposure. International journal of cosmetic science, 2026
Studies in people come first, then studies in animals and in the lab.
Status unknown.
Status unknown.
Status unknown.
Regulatory status not recorded. Status unknown.
Laws and labels change, so check the regulator for the current status.
PepBank has 1 safety result from studies of palmitoyl tetrapeptide-7. None of them come from studies in people, so they do not show what happens in people.
What people report online. It comes from forums and guides, not from studies.
A cosmetic safety assessment reports skin-conditioning use of this ingredient. This use report does not establish isolated clinical efficacy or safety.
| Context | Route | Amount | How often | How long | Agreement | Sources |
|---|---|---|---|---|---|---|
| Skin conditioning in cosmetic products | Not stated | Not stated | Not stated | Not stated | One safety assessment. The EPA record mirrors its abstract and is not a second independent source. | S1 |
Gaps
The assessment identifies cosmetic use. The quote does not establish an amount, route, frequency or duration. It does not establish isolated clinical outcomes.
The answer links to every study it uses.
AI wrote and checked these results. AI can make mistakes, so check important results against the source.
PepBank is a research reference. Talk to a doctor before you use any peptide.
Ask your AI about palmitoyl tetrapeptide-7
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In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated