Peptides / Skin and hair
Synthetic analog · 8 amino acids · 1,075.2 Da
SNAP-8 (acetyl octapeptide-3)
Not approved
SNAP-8, also called acetyl octapeptide-3, is a synthetic peptide used in skin products for expression lines. It is listed as an EU cosmetic ingredient, not approved as a drug, and studies so far tested it only mixed with other ingredients. PepBank shows no results on SNAP-8 from studies in people, animals, the lab or computer predictions. Data as of 2026-10-30.
Also known as Ac-EEMQRRAD-NH2, Acetyl Octapeptide-3, SNAP-8
8 amino acids, from first to lastEEMQRRAD
Evidence level: No study results yetPepBank has no study results for SNAP-8 yet.
Results in people
0
0% of 0 results
Results in animals
0
0% of 0 results
Results in lab cells
0
0% of 0 results
From computer models
0
0% of 0 results
Overview
SNAP-8 (acetyl octapeptide-3) at a glance
| What it is | Synthetic analog, 8 amino acids |
|---|---|
| Approval | Not approved for any use |
| In sport | Status unknown |
| Studies | 2 studies with results. None of them gave SNAP-8. |
| Clinical trials | None registered |
| Community use | Expression line appearance |
The science
What is SNAP-8?
An acetylated octapeptide used in topical cosmetics for expression lines.
8
Amino acids in one chain
SNAP-8 (acetyl octapeptide-3) structure and chemistry
The key facts about the molecule. Long codes are in the closed section below.
Sequence, 8 amino acidsFrom the first amino acid to the last
−E1−EMQ+R5+RA−D
Darker means more water-repelling+ and − show charge in the bodyOutlined: changed amino acid
Structure
SNAP-8 (acetyl octapeptide-3) is a synthetic analog of 8 amino acids, with no ring, 2 changed amino acids.
Formula
C41H70N16O16S
Molecular weight
1,075.2 g/mol
Development
Highest phase: unknown.
Identifiers
Full sequence, SMILES and InChIKey
InChIKeyKMACPCJUCHVVGP-FNRPHRCSSA-N
SMILESC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)C
The evidence
What SNAP-8 studies show
Results grouped by what the studies measured. Each card shows where its results come from.
No study results yetPepBank has no study results for SNAP-8 yet.
Key SNAP-8 studies
No study of SNAP-8 has results in PepBank yet.
SNAP-8 clinical trials
ClinicalTrials.gov lists no trial of SNAP-8. A trial under another name may exist.
Status and safety
Is SNAP-8 approved?
FDA
United States
Not approvedNo approved medicine contains it.
EMA
European Union
Not approvedNo approved medicine contains it.
WADA
Sport
Not recordedStatus unknown.
No. Not approved for any use. The FDA, the EMA and the other sources we use show no approval (as of 22 Oct 2026). Status unknown.
Laws and labels change, so check the regulator for the current status.
SNAP-8 side effects and safety
PepBank has no safety result from studies of SNAP-8 yet. That does not mean SNAP-8 is safe.
From the community
How people use it
What people report online. It comes from forums and guides, not from studies.
Community-reported. Not tested in trials.
The source describes topical cosmetic use. These reports do not establish a safe or effective concentration.
Reported routines and cautions
What people use it for
- Expression line appearanceS1
Reported regimens
| Context | Route | Amount | How often | How long | Agreement | Sources |
|---|---|---|---|---|---|---|
| Reported cosmetic serum | topical | 3 to 10 % per supplier solution incorporated into the finished cosmetic formulation | twice daily | ongoing, minimum 4 to 8 weeks | One community aggregation source. A supplier confirms the solution convention. No independent user reports were checked. | S1 |
Cautions
- The guide does not establish clinical safety or efficacy. The 3-10% supplier use rate applies to solution containing 0.05% peptide. It does not mean 3-10% pure peptide.S1
Community sources
- S1SNAP-8 community guide (opens in a new tab)peptideprotocolwiki.com
plus 1 seller page (not linked)
Gaps
S1 describes AI-generated aggregation and labels the page unverified. Underlying user reports were not independently checked. No Reddit pages were accessed. Actual concentrations in reported serums remain unverified. Source statements do not establish safety, efficacy, or an approved dose.
Questions and more
Ask a question about SNAP-8
The answer links to every study it uses.
Sources
- Database: PepBank data for SNAP-8 (data version 308560)
- Regulator: FDA status record
- Regulator: EMA status record
- Regulator: WADA status record
- Community: community sources (forums and guides), as summarized in the PepBank community file
AI wrote and checked these results. AI can make mistakes, so check important results against the source.
PepBank is a research reference. Talk to a doctor before you use any peptide.
Ask your AI about SNAP-8
Curo is a peptide shop. PepBank and Curo have the same owner. See the Curo catalog (opens in a new tab).