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Exenatide (exendin-4) studies: 530 papers with results

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  1. Combined exenatide and dapagliflozin has no additive effects on reduction of hepatocellular lipids despite better glycaemic control in patients with type 2 diabetes mellitus treated with metformin: EXENDA, a 24-week, prospective, randomized, placebo-controlled pilot trial.

    Harreiter J · Diabetes, obesity & metabolism · 2021

    Randomized controlled trial · 7 results

  2. Treatment of clozapine-associated obesity and diabetes with exenatide in adults with schizophrenia: A randomized controlled trial (CODEX).

    Siskind DJ · Diabetes, obesity & metabolism · 2018

    Randomized controlled trial · 6 results

  3. The effect of exenatide on lisinopril pharmacodynamics and pharmacokinetics in patients with hypertension.

    Linnebjerg H · International journal of clinical pharmacology and therapeutics · 2009

    Randomized controlled trial · 5 results

  4. Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety.

    Nathanson D · Diabetologia · 2012

    Randomized controlled trial · 8 results

  5. Prehospital exenatide in hyperglycemic stroke-A randomized trial.

    Larsson M · Acta neurologica Scandinavica · 2019

    Randomized controlled trial · 2 results

  6. The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial.

    Mitchell JL · Brain : a journal of neurology · 2023

    Randomized controlled trial · 4 results

  7. Effect of exenatide, sitagliptin, or glimepiride on β-cell secretory capacity in early type 2 diabetes.

    Gudipaty L · Diabetes care · 2014

    Randomized controlled trial · 4 results

  8. Pharmacology and tolerability of a single dose of exenatide in adolescent patients with type 2 diabetes mellitus being treated with metformin: a randomized, placebo-controlled, single-blind, dose-escalation, crossover study.

    Malloy J · Clinical therapeutics · 2009

    Randomized controlled trial · 11 results

  9. Exenatide as a weight-loss therapy in extreme pediatric obesity: a randomized, controlled pilot study.

    Kelly AS · Obesity (Silver Spring, Md.) · 2012

    Randomized controlled trial · 7 results

  10. Glucagon-like peptide-1 receptor agonist exenatide has no acute effect on MRI-measured exocrine pancreatic function in patients with type 2 diabetes: a randomized trial.

    Smits MM · Diabetes, obesity & metabolism · 2016

    Randomized controlled trial · 4 results

  11. Exenatide corrects postprandial hyperglycaemia in young people with cystic fibrosis and impaired glucose tolerance: A randomized crossover trial.

    Geyer MC · Diabetes, obesity & metabolism · 2019

    Randomized controlled trial · 7 results

  12. Use of twice-daily exenatide in Basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial.

    Buse JB · Annals of internal medicine · 2011

    Randomized controlled trial · 10 results

  13. Comparison of single and combined treatment with exenatide and metformin on menstrual cyclicity in overweight women with polycystic ovary syndrome.

    Elkind-Hirsch K · The Journal of clinical endocrinology and metabolism · 2008

    Randomized controlled trial · 13 results

  14. The fate of taspoglutide, a weekly GLP-1 receptor agonist, versus twice-daily exenatide for type 2 diabetes: the T-emerge 2 trial.

    Rosenstock J · Diabetes care · 2013

    Randomized controlled trial · 15 results

  15. Comparison of the effects on glycaemic control and β-cell function in newly diagnosed type 2 diabetes patients of treatment with exenatide, insulin or pioglitazone: a multicentre randomized parallel-group trial (the CONFIDENCE study).

    Xu W · Journal of internal medicine · 2015

    Randomized controlled trial · 5 results

  16. Exenatide at therapeutic and supratherapeutic concentrations does not prolong the QTc interval in healthy subjects.

    Darpö B · British journal of clinical pharmacology · 2013

    Randomized controlled trial · 4 results

  17. Albuminuria-lowering effect of dapagliflozin, exenatide, and their combination in patients with type 2 diabetes: A randomized cross-over clinical study.

    van der Aart-van der Beek AB · Diabetes, obesity & metabolism · 2023

    Randomized controlled trial · 16 results

  18. Impact of exenatide on weight loss and eating behavior in adults with craniopharyngioma-related obesity: the CRANIOEXE randomized placebo-controlled trial.

    Gatta-Cherifi B · European journal of endocrinology · 2024

    Randomized controlled trial · 4 results

  19. Comparing the effects of twice-daily exenatide and insulin on renal function in patients with type 2 diabetes mellitus: secondary analysis of a randomized controlled trial.

    Zhang J · Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022

    Randomized controlled trial · 5 results

  20. Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes Mellitus With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial.

    Fudim M · Circulation · 2019

    Randomized controlled trial · 7 results

  21. Within-Trial Evaluation of Medical Resources, Costs, and Quality of Life Among Patients With Type 2 Diabetes Participating in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).

    Reed SD · Diabetes care · 2020

    Randomized controlled trial · 9 results

  22. Effect of short-acting exenatide administered three times daily on markers of cardiovascular disease in type 1 diabetes: A randomized double-blind placebo-controlled trial.

    Johansen NJ · Diabetes, obesity & metabolism · 2020

    Randomized controlled trial · 10 results

  23. Exenatide Adjunct to Nicotine Patch Facilitates Smoking Cessation and May Reduce Post-Cessation Weight Gain: A Pilot Randomized Controlled Trial.

    Yammine L · Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021

    Randomized controlled trial · 5 results

  24. Effect of exenatide twice daily and dapagliflozin, alone and in combination, on markers of kidney function in obese patients with type 2 diabetes: A prespecified secondary analysis of a randomized controlled clinical trial.

    van Ruiten CC · Diabetes, obesity & metabolism · 2021

    Randomized controlled trial · 6 results

  25. Mechanisms underlying the blood pressure lowering effects of dapagliflozin, exenatide, and their combination in people with type 2 diabetes: a secondary analysis of a randomized trial.

    van Ruiten CC · Cardiovascular diabetology · 2022

    Randomized controlled trial · 7 results

  26. A double-blind, placebo-controlled trial of exenatide for the treatment of olanzapine-related weight gain in obese and overweight adults.

    Patino LR · Journal of affective disorders · 2025

    Randomized controlled trial · 5 results

  27. Effects of exenatide versus insulin analogues on weight change in subjects with type 2 diabetes: a pooled post-hoc analysis.

    Glass LC · Current medical research and opinion · 2008

    Randomized controlled trial · 5 results

  28. Exenatide once weekly decreases urinary albumin excretion in patients with type 2 diabetes and elevated albuminuria: Pooled analysis of randomized active controlled clinical trials.

    van der Aart-van der Beek AB · Diabetes, obesity & metabolism · 2020

    Randomized controlled trial · 9 results

  29. Exenatide twice daily versus insulin glargine for the treatment of type 2 diabetes in Poland - subgroup data from a randomised multinational trial GWAA.

    Matyjaszek-Matuszek B · Endokrynologia Polska · 2013

    Randomized controlled trial · 12 results

  30. What Effects Might Exenatide have on Non-Motor Symptoms in Parkinson's Disease: A Post Hoc Analysis.

    Athauda D · Journal of Parkinson's disease · 2018

    Randomized controlled trial · 5 results

  31. Efficacy and Safety Over 2 Years of Exenatide Plus Dapagliflozin in the DURATION-8 Study: A Multicenter, Double-Blind, Phase 3, Randomized Controlled Trial.

    Jabbour SA · Diabetes care · 2020

    Randomized controlled trial · 5 results

  32. Brain Activation in Response to Low-Calorie Food Pictures: An Explorative Analysis of a Randomized Trial With Dapagliflozin and Exenatide.

    van Ruiten CC · Frontiers in endocrinology · 2022

    Randomized controlled trial · 5 results

  33. Risk factors for bone fractures in type 2 diabetes and the impact of once-weekly exenatide: insights from an EXSCEL post-hoc analysis.

    Maddaloni E · Diabetes research and clinical practice · 2025

    Randomized controlled trial · 1 result

  34. Effect of race on cardiometabolic responses to once-weekly exenatide: insights from the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).

    Davis TME · Cardiovascular diabetology · 2022

    Randomized controlled trial · 7 results

  35. Long-term changes in cardiovascular risk markers during administration of exenatide twice daily or glimepiride: results from the European exenatide study.

    Simó R · Cardiovascular diabetology · 2015

    Randomized controlled trial · 12 results

  36. Efficacy and tolerability of exenatide once weekly versus sitagliptin in patients with type 2 diabetes mellitus: a retrospective analysis of pooled clinical trial data.

    Malloy J · Postgraduate medicine · 2013

    Randomized controlled trial · 8 results

  37. Efficacy and safety of exenatide once-weekly vs exenatide twice-daily in Asian patients with type 2 diabetes mellitus.

    Ji L · Journal of diabetes investigation · 2013

    Randomized controlled trial · 14 results

  38. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial.

    Heine RJ · Annals of internal medicine · 2005

    Randomized controlled trial · 11 results

  39. A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a non-inferiority study.

    Nauck MA · Diabetologia · 2007

    Randomized controlled trial · 9 results

  40. Patient-reported outcomes in a trial of exenatide and insulin glargine for the treatment of type 2 diabetes.

    Secnik Boye K · Health and quality of life outcomes · 2006

    Randomized controlled trial · 2 results

  41. Safety and efficacy of once-weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes over 84 weeks.

    Diamant M · Diabetes care · 2012

    Randomized controlled trial · 8 results

  42. Patient-reported outcomes are superior in patients with Type 2 diabetes treated with liraglutide as compared with exenatide, when added to metformin, sulphonylurea or both: results from a randomized, open-label study.

    Schmidt WE · Diabetic medicine : a journal of the British Diabetic Association · 2011

    Randomized controlled trial · 18 results

  43. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes.

    Buse JB · Diabetes care · 2004

    Randomized controlled trial · 8 results

  44. Exenatide twice daily versus premixed insulin aspart 70/30 in metformin-treated patients with type 2 diabetes: a randomized 26-week study on glycemic control and hypoglycemia.

    Gallwitz B · Diabetes care · 2011

    Randomized controlled trial · 4 results

  45. Exenatide effects on statin pharmacokinetics and lipid response.

    Kothare PA · International journal of clinical pharmacology and therapeutics · 2007

    Randomized controlled trial · 8 results

  46. Improved treatment satisfaction and weight-related quality of life with exenatide once weekly or twice daily.

    Best JH · Diabetic medicine : a journal of the British Diabetic Association · 2009

    Randomized controlled trial · 10 results

  47. Exenatide once weekly versus daily basal insulin as add-on treatment to metformin with or without a sulfonylurea: a retrospective pooled analysis in patients with poor glycemic control.

    Grimm M · Postgraduate medicine · 2013

    Randomized controlled trial · 5 results

  48. DURATION-1: exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks.

    Buse JB · Diabetes care · 2010

    Randomized controlled trial · 8 results

  49. Efficacy and safety of exenatide once weekly versus metformin, pioglitazone, and sitagliptin used as monotherapy in drug-naive patients with type 2 diabetes (DURATION-4): a 26-week double-blind study.

    Russell-Jones D · Diabetes care · 2012

    Randomized controlled trial · 10 results

  50. Exenatide compared with long-acting insulin to achieve glycaemic control with minimal weight gain in patients with type 2 diabetes: results of the Helping Evaluate Exenatide in patients with diabetes compared with Long-Acting insulin (HEELA) study.

    Davies MJ · Diabetes, obesity & metabolism · 2009

    Randomized controlled trial · 7 results

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