PepBank has 1 acetyl tetrapeptide-5 study with results. It gave acetyl tetrapeptide-5, with 1 result, grouped by what the studies measured. In each group, results from studies in people come first. Data as of 2026-10-30.
Searches 1 result and 1 paper. Newer studies from Europe PMC
Identifiers, parent molecule, targets and development stage, from curated data.
Acetyl tetrapeptide-5 contains N-acetyl-beta-alanine followed by histidine, serine and histidine. Eyeseryl is a commercial ingredient solution containing this peptide. The solution percentage differs from the pure peptide percentage.
No molecular target is recorded for this peptide.
Residues, differences from the parent, calculated properties and 3D structure. Source values and calculated values are shown separately.
4 amino acids · 2 modifications
Some values cannot be calculated. The sequence has a non-canonical residue (X). Residue tables cover only the 20 standard amino acids.
@pepdb/chem 0.2.0 · EMBOSS pKa set · ExPASy residue masses
No charge curve
The sequence has a non-canonical residue (X). Residue tables cover only the 20 standard amino acids.
4 residues. Each residue counts in one class; F and W count as aromatic.
No 3D structure
No experimental structure (PDB) and no UniProt entry for an AlphaFold model are listed for this peptide. Synthetic peptides often have neither. The sequence view above is the reference.
Draws the structure in your browser with RDKit (about 2.3 MB, loaded once).
SMILES fromPubChem CID 11620163(opens in a new tab)
CC(=O)NCCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC2=CN=CN2)C(=O)OPeople first in each area, then animals, then lab cells. Counts are exact and come from studies that gave the peptide.
PepBank reads each paper before it shows the results. This search looks in Europe PMC for newer papers that PepBank has not read yet.
Counts are exact and come from studies that gave the peptide.
Studies by year
1 of 1 study has results (100%), published 2021. Top row: every study. Bottom row: studies with results about Acetyl tetrapeptide-5, by class. The rows use different scales.
Studies1 in all, 2021
Studies with results1 in all, 2021
Retracted studies are left out. A study with results in two classes counts in both.
AI wrote and checked these results. AI can make mistakes, so check important results against the source.
Registered trials that test the peptide, with phase, status and dates. A dot marks trials with posted results.
0 trials match. Highest phase first. Data from ClinicalTrials.gov.
No trial matches these filters.
Studies on this peptide. Some have results. The others have none yet.
1 study matches. Retracted studies are left out.
Showing 1 of 1 studyquery qry_ec1e80f294654145f77d1f38
1 study
Other design · 2021
Wu et al. 2021Skin pharmacology and physiologycited by 10
PMID 33849044DOI 10.1159/000514496PUB-33849044
Page 1 of 1
Wu Y · Skin pharmacology and physiology · 2021
Other design · 14 results
Approval and sport status, and the safety outcomes reported in study results. Laws and labels change, so check the regulator for the current status.
| Jurisdiction | Body | Status | As of | Source |
|---|---|---|---|---|
| US | FDA | DailyMed lists Derma Firm Eye, containing acetyl tetrapeptide-5 and acetyl octapeptide-3, as unapproved drug other. Its labeling is not FDA approved. This listing and the UNII do not establish approval of the peptide. | 27 Oct 2026 | dailymed.nlm.nih.gov (opens in a new tab) |
| EU | EMA | No product-specific EMA authorisation was established by the targeted agency-domain search. This does not exclude national authorisations. Cosmetic ingredient listing does not establish medicinal authorisation. | 27 Oct 2026 | Not recorded |
| Sport | WADA | Status unknown The 2026 list does not name acetyl tetrapeptide-5 or Eyeseryl. | 2026 List | wada-ama.org (opens in a new tab) |
| European Union | Note | INCI: ACETYL TETRAPEPTIDE-5. CosIng reference 54142. Secondary ingredient dictionaries report this entry. The official page did not return the ingredient detail during this check. An inventory entry is not a medicinal approval. | 27 Oct 2026 | specialchem.com (opens in a new tab) |
| Canada | Note | Health Canada NHPID lists a non-medicinal skin-conditioning ingredient for topical use only. Approved Chemical Name describes nomenclature, not medicine approval. | 27 Oct 2026 | webprod.hc-sc.gc.ca (opens in a new tab) |
Reported effects from study results.
No safety results from studies in people
The doses that these studies used. They are not recommendations.
100 μg/mLLab
PepBank is a research reference. Talk to a doctor before you use any peptide.
Data version, change history and code for this peptide.
curl -s https://Evidence summary for Acetyl tetrapeptide-5: counts by class, key results with sources, notices, data version.
In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated
Top outcomes
The 1 outcome groups with the most study results, by evidence class.
Data version 308560. Bar length is the number of results, not the size of an effect.
Evidence matrix
Study results by outcome and evidence class. Arrows show how the measured outcome moved, not whether the change is good.
| Outcome group | Human | Animal | Lab | Computer model | Total |
|---|---|---|---|---|---|
| Receptor activity and mechanismPharmacology | No results | No results | Lab: 1 result from 1 study: 1 not reported. Strongest design: Other design | No results | 1 |
1 outcome group shown of 1 · 1 study result
Data version 308560. Shade grows with the number of results. Every cell shows the exact count.