The Effect of Byetta and Symlin on Post-meal Meal Blood Sugar Levels in Children With Type 2 Diabetes

Inclusion Criteria: * Children with Type 2 Diabetes, * Between the ages of 12-21 years, * Tanner stage 4-5 for pubertal development, * Menstruating females must have a negative urine pregnancy test for inclusion, * Must have T2DM for at least 6 months, * History of negative anti-glutamic acid decarboxylase (GAD) -65 and anti-islet cell antibodies, * HbA1c \< 8.5% and on a stable dose of an oral hypoglycemic agent (with or without insulin) over the last 2 months, or well controlled on diet. Exclusion Criteria: * A history of a chronic disease other than diabetes (leukemia, asthma, inflammatory bowel disease, cystic fibrosis, juvenile rheumatoid arthritis, dyslipidemia, cholelithiasis etc), * BMI\> 40 kg/m2, * Weight of \< 60 kg, * Female with menstrual irregularities, * Allergy to local anesthetics (ELAMAX Cream, Ethyl Chloride), * Evidence or history of chemical abuse, * Anemia (age specific normal range for hemoglobin will be used), * Elevated liver enzymes (defined as more than 3 times the upper limit of the normal range for age), * Elevated BUN or creatinine (defined as more than 3 times the upper limit of the normal range for age), * Use of medications that may increase the blood sugars and admission to the hospital for diabetes related problems over the last 6 months.