In people with obesity and type 1 diabetes, liraglutide use was associated with a 0.23% HbA1c reduction over 12 months.
In plain wordsIn people with type 1 diabetes and obesity, liraglutide use was linked to a 0.23% HbA1c reduction.
- Peptide
- Liraglutide
- Outcome
- DecreaseHbA1c
- Study
n = 97
- Analysis
- Secondary
- Outcome group
- Glycemic control · Metabolic and weight
- Studied dose
- Dose not stated · 12 monthsAs given in this study (human).
Measurements
- HbA1c reduction
- 0.23%
- liraglutide
- P value
- 0.017
- liraglutide HbA1c reduction
Source sentences
Tirzepatide, semaglutide and liraglutide modestly reduced HbA1c by 0.65% (p = 0.004), 0.33% (p = 0.034) and 0.23% (p = 0.017), respectively.
3 context sentences(design, population, supporting numbers)
This study aimed to compare the effects of tirzepatide, semaglutide, and liraglutide on body weight and metabolic risk markers over 12 months in people with body mass index ≥27 kg/m2 and type 1 diabetes (T1D).
This real-world study included 250 people with obesity and T1D (female = 54.8%), treated with either tirzepatide (n = 35), semaglutide (n = 36), liraglutide (n = 97) or usual care (n = 82).
Secondary outcomes included changes in lipid profile, renal and liver markers, blood pressure, and HbA1c.