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Setmelanotide clinical trials: 15 trials

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Read 15 Setmelanotide clinical trials with posted results or linked papers with results in PepBank.

  1. Long Term Extension Trial of Setmelanotide

    NCT03651765 · Phase 2/3 · Completed

    Posted results

  2. A Trial of Setmelanotide in Acquired Hypothalamic Obesity

    NCT05774756 · Phase 3 · Active, not recruiting

    Posted results

  3. Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants

    NCT05046132 · Phase 4 · Completed

    Posted results

  4. Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

    NCT03746522 · Phase 3 · Completed

    Posted results

  5. Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R Pathway

    NCT05194124 · Phase 3 · Completed

    Posted results

  6. Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

    NCT02896192 · Phase 3 · Completed

    Posted results

  7. Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

    NCT03287960 · Phase 3 · Completed

    Posted results

  8. Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity

    NCT04966741 · Phase 3 · Completed

    Posted results

  9. Real-World Effects of MC4R Agonist Therapy in BBS and Severe Genetic Obesity

    NCT07674290 · Phase 4 · Recruiting

    Linked paper with results

  10. Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

    NCT03013543 · Phase 2 · Completed

    Posted results

  11. DAYBREAK: A Study of Setmelanotide in Participants With Specific Gene Variants in the Melanocortin-4 Receptor (MC4R) Pathway

    NCT04963231 · Phase 2 · Completed

    Posted results

  12. Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients

    NCT02041195 · Phase 1/2 · Completed

    Posted results

  13. Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants

    NCT01749137 · Phase 2 · Completed

    Posted results

  14. Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome

    NCT02311673 · Phase 2 · Completed

    Posted results

  15. Open-Label Study of Setmelanotide in Hypothalamic Obesity

    NCT04725240 · Phase 2 · Completed

    Posted results

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