Palmitoyl tripeptide-1, also called pal-GHK, is a palmitoylated form of the peptide GHK used in skin care, different from GHK-Cu and not an approved drug. Lab studies in skin cells tested it mostly on collagen. PepBank shows 3 results on palmitoyl tripeptide-1 from animal and lab studies. No study in people has reported results yet. Data as of 2026-10-30.
Also known as pal-GHK, palmitoyl tripeptide 1, palmitoyl-GHK
| What it is | Modified form, 3 amino acids |
|---|---|
| Approval | Regulatory status not recorded |
| In sport | Status unknown |
| Studies | 4 studies with results. 2 of them gave palmitoyl tripeptide-1, with 3 results. 3 in lab cells |
| Clinical trials | None registered |
| Community use | Skin conditioning in cosmetic products |
A palmitoylated GHK peptide used in skin-conditioning cosmetics.
Amino acids in one chain
The key facts about the molecule. Long codes are in the closed section below.
Three-letter sequenceGly-His-Lys
InChIKeyBYUQATUKPXLFLZ-UIOOFZCWSA-N
SMILESCCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)O
Results grouped by what the studies measured. Each card shows where its results come from.
In cells, PT-1 increased nighttime collagen production. Journal of cosmetic dermatology, 2026
Studies in people come first, then studies in animals and in the lab.
Status unknown.
Status unknown.
Status unknown.
Regulatory status not recorded. Status unknown.
Laws and labels change, so check the regulator for the current status.
PepBank has 1 safety result from studies of palmitoyl tripeptide-1. None of them come from studies in people, so they do not show what happens in people.
What people report online. It comes from forums and guides, not from studies.
The CIR safety assessment reports cosmetic use of palmitoyl tripeptide-1. This report does not establish isolated clinical efficacy or a quantified regimen.
| Context | Route | Amount | How often | How long | Agreement | Sources |
|---|---|---|---|---|---|---|
| Skin conditioning in cosmetic products | Not stated | Not stated | Not stated | Not stated | Single safety assessment, reproduced in EPA HERO. These are not two independent reports. | S1 |
Gaps
No quoted amount, route, frequency or duration establishes a regimen. No independent community outcome report was established.
The answer links to every study it uses.
AI wrote and checked these results. AI can make mistakes, so check important results against the source.
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In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated