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Dulaglutide (Trulicity) studies: 418 papers with results

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  1. Effects of the once-weekly glucagon-like peptide-1 receptor agonist dulaglutide on ambulatory blood pressure and heart rate in patients with type 2 diabetes mellitus.

    Ferdinand KC · Hypertension (Dallas, Tex. : 1979) · 2014

    Randomized controlled trial · 6 results

  2. Once-weekly glucagon-like peptide-1 receptor agonist dulaglutide is non-inferior to once-daily liraglutide and superior to placebo in Japanese patients with type 2 diabetes: a 26-week randomized phase III study.

    Miyagawa J · Diabetes, obesity & metabolism · 2015

    Randomized controlled trial · 15 results

  3. Monotherapy with the once weekly GLP-1 receptor agonist dulaglutide for 12 weeks in Japanese patients with type 2 diabetes: dose-dependent effects on glycaemic control in a randomised, double-blind, placebo-controlled study.

    Terauchi Y · Endocrine journal · 2014

    Randomized controlled trial · 12 results

  4. Efficacy and safety of an expanded dulaglutide dose range: A phase 2, placebo-controlled trial in patients with type 2 diabetes using metformin.

    Frias JP · Diabetes, obesity & metabolism · 2019

    Randomized controlled trial · 12 results

  5. Achieving the composite end-point of glycated hemoglobin <7.0% without weight gain or hypoglycemia with once-weekly dulaglutide in Chinese patients with type 2 diabetes: A post-hoc analysis.

    Xiao X · Journal of diabetes investigation · 2020

    Randomized controlled trial · 5 results

  6. Gender differences in weight gain during attempted and successful smoking cessation on dulaglutide treatment: a predefined secondary analysis of a randomised trial.

    Baur F · BMJ nutrition, prevention & health · 2023

    Randomized controlled trial · 4 results

  7. Effects of dulaglutide on alcohol consumption during smoking cessation.

    Probst L · JCI insight · 2023

    Randomized controlled trial · 2 results

  8. Improvement in treatment satisfaction after switching from liraglutide to dulaglutide in patients with type 2 diabetes: A randomized controlled trial.

    Takase T · Journal of diabetes investigation · 2019

    Randomized controlled trial · 10 results

  9. Blood pressure changes during smoking cessation in a randomized, double-blind, placebo-controlled trial of dulaglutide treatment.

    Beck J · European journal of preventive cardiology · 2025

    Randomized controlled trial · 7 results

  10. A comparison of the effects of tirzepatide and dulaglutide on major kidney events in people with type 2 diabetes: pre-specified exploratory analyses of the SURPASS-CVOT trial.

    Zoungas S · The lancet. Diabetes & endocrinology · 2026

    Randomized controlled trial · 19 results

  11. Dulaglutide and renal outcomes in type 2 diabetes: an exploratory analysis of the REWIND randomised, placebo-controlled trial.

    Gerstein HC · Lancet (London, England) · 2019

    Randomized controlled trial · 4 results

  12. The effect of dulaglutide on stroke: an exploratory analysis of the REWIND trial.

    Gerstein HC · The lancet. Diabetes & endocrinology · 2020

    Randomized controlled trial · 6 results

  13. Glycaemic control, body weight, and safety of tirzepatide versus dulaglutide by baseline glycated haemoglobin level in Japanese patients with type 2 diabetes: A subgroup analysis of the SURPASS J-mono study.

    Osonoi T · Diabetes, obesity & metabolism · 2024

    Randomized controlled trial · 16 results

  14. Efficacy and safety of subgroup analysis stratified by baseline HbA1c in a Japanese phase 3 study of dulaglutide 0.75 mg compared with insulin glargine in patients with type 2 diabetes.

    Kaneko S · Endocrine journal · 2017

    Randomized controlled trial · 11 results

  15. Effects of Tirzepatide, a Dual GIP and GLP-1 RA, on Lipid and Metabolite Profiles in Subjects With Type 2 Diabetes.

    Pirro V · The Journal of clinical endocrinology and metabolism · 2022

    Randomized controlled trial · 11 results

  16. Effect of dulaglutide 3.0 and 4.5 mg on weight in patients with type 2 diabetes: Exploratory analyses of AWARD-11.

    Bonora E · Diabetes, obesity & metabolism · 2021

    Randomized controlled trial · 8 results

  17. Clinical Outcomes by Albuminuria Status with Dulaglutide versus Insulin Glargine in Participants with Diabetes and CKD: AWARD-7 Exploratory Analysis.

    Tuttle KR · Kidney360 · 2021

    Randomized controlled trial · 3 results

  18. Patient-reported Outcomes in Patients with Type 2 Diabetes Treated with Dulaglutide Added to Titrated Insulin Glargine (AWARD-9).

    Yu M · Clinical therapeutics · 2017

    Randomized controlled trial · 8 results

  19. Orforglipron, an oral non-peptide glucagon-like peptide-1 receptor agonist, improves markers of β-cell function and insulin sensitivity in type 2 diabetes.

    Rosenstock J · Diabetes, obesity & metabolism · 2025

    Randomized controlled trial · 17 results

  20. Change in HbA1c Across the Baseline HbA1c Range in Type 2 Diabetes Patients Receiving Once-Weekly Dulaglutide Versus Other Incretin Agents.

    Gentilella R · Diabetes therapy : research, treatment and education of diabetes and related disorders · 2019

    Randomized controlled trial · 9 results

  21. Evaluation of the impact of once weekly dulaglutide on patient-reported outcomes in Japanese patients with type 2 diabetes: comparisons with liraglutide, insulin glargine, and placebo in two randomized studies.

    Suzuki S · Health and quality of life outcomes · 2017

    Randomized controlled trial · 4 results

  22. Efficacy and Safety of Once-Weekly Dulaglutide in Type 2 Diabetes Patients Using Insulin: Exploratory Subgroup Analysis by Insulin Regimen.

    Onishi Y · Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020

    Randomized controlled trial · 8 results

  23. Efficacy of Dulaglutide Expanded Doses by Baseline A1C Categories: Post Hoc Analysis of AWARD-11

    Frias J · Journal of the Endocrine Society · 2021

    Randomized controlled trial · 28 results

  24. Dulaglutide and cardiovascular and heart failure outcomes in patients with and without heart failure: a post-hoc analysis from the REWIND randomized trial.

    Branch KRH · European journal of heart failure · 2022

    Randomized controlled trial · 5 results

  25. Total cardiovascular or fatal events in people with type 2 diabetes and cardiovascular risk factors treated with dulaglutide in the REWIND trail: a post hoc analysis.

    Dagenais GR · Cardiovascular diabetology · 2020

    Randomized controlled trial · 2 results

  26. Dulaglutide and incident atrial fibrillation or flutter in patients with type 2 diabetes: A post hoc analysis from the REWIND randomized trial.

    Raubenheimer PJ · Diabetes, obesity & metabolism · 2022

    Randomized controlled trial · 3 results

  27. Once-weekly dulaglutide versus insulin glargine in the early control of fasting serum glucose and HbA1c.

    Romera I · Journal of diabetes and its complications · 2020

    Randomized controlled trial · 3 results

  28. Differential effects of once-weekly glucagon-like peptide-1 receptor agonist dulaglutide and metformin on pancreatic β-cell and insulin sensitivity during a standardized test meal in patients with type 2 diabetes.

    Mari A · Diabetes, obesity & metabolism · 2016

    Randomized controlled trial · 7 results

  29. Insulin Sensitivity and Beta-Cell Function Following Tirzepatide in Japanese Patients with Type 2 Diabetes: A SURPASS J-mono Analysis.

    Hamamoto Y · Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025

    Randomized controlled trial · 40 results

  30. A 24-week study to evaluate the efficacy and safety of once-weekly dulaglutide added on to glimepiride in type 2 diabetes (AWARD-8).

    Dungan KM · Diabetes, obesity & metabolism · 2016

    Randomized controlled trial · 9 results

  31. Efficacy and Safety of Dulaglutide Monotherapy Compared to Glimepiride in Oral Antihyperglycemic Medication-Naïve Chinese patients with Type 2 Diabetes: A Post Hoc Analysis of AWARD-CHN1.

    Li YM · Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020

    Randomized controlled trial · 11 results

  32. The effects of LY2189265, a long-acting glucagon-like peptide-1 analogue, in a randomized, placebo-controlled, double-blind study of overweight/obese patients with type 2 diabetes: the EGO study.

    Umpierrez GE · Diabetes, obesity & metabolism · 2011

    Randomized controlled trial · 12 results

  33. Pancreatic Safety of Once-Weekly Dulaglutide in Chinese Patients with Type 2 Diabetes Mellitus: Subgroup Analysis by Potential Influencing Factors.

    Zhou Y · Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021

    Randomized controlled trial · 12 results

  34. Once-Weekly Dulaglutide with Insulin Therapy for Type 2 Diabetes: Efficacy and Safety Results from a Phase 4, Randomized, Placebo-Controlled Study.

    Ishii H · Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020

    Randomized controlled trial · 9 results

  35. Pharmacoeconomic analysis (CER) of Dulaglutide and Liraglutide in the treatment of patients with type 2 diabetes.

    Su Y · Frontiers in endocrinology · 2023

    Randomized controlled trial · 15 results

  36. Dulaglutide-combined basal plus correction insulin therapy contributes to ideal glycemic control in non-critical hospitalized patients.

    Fushimi N · Journal of diabetes investigation · 2020

    Randomized controlled trial · 8 results

  37. Effects of GLP-1 receptor agonists on copeptin in euvolemic participants.

    Leibnitz S · European journal of endocrinology · 2026

    Randomized controlled trial · 4 results

  38. Effect of a 3-Week Treatment with GLP-1 Receptor Agonists on Vasoactive Hormones in Euvolemic Participants.

    Vukajlovic T · The Journal of clinical endocrinology and metabolism · 2022

    Randomized controlled trial · 7 results

  39. Change in pharmacodynamic variables following once-weekly tirzepatide treatment versus dulaglutide in Japanese patients with type 2 diabetes (SURPASS J-mono substudy).

    Yabe D · Diabetes, obesity & metabolism · 2023

    Randomized controlled trial · 12 results

  40. Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial.

    Coskun T · The lancet. Diabetes & endocrinology · 2025

    Randomized controlled trial · 18 results

  41. Effects of dulaglutide on endothelial progenitor cells and arterial elasticity in patients with type 2 diabetes mellitus.

    Xie D · Cardiovascular diabetology · 2022

    Randomized controlled trial · 14 results

  42. The Effects of Once-Weekly Dulaglutide and Insulin Glargine on Glucose Fluctuation in Poorly Oral-Antidiabetic Controlled Patients with Type 2 Diabetes Mellitus.

    Wang J · BioMed research international · 2019

    Randomized controlled trial · 19 results

  43. Effects of the glucagon-like peptide-1 receptor agonist dulaglutide on sexuality in healthy men: a randomised, double-blind, placebo-controlled crossover study.

    Lengsfeld S · EBioMedicine · 2024

    Randomized controlled trial · 6 results

  44. A Randomized Study to Compare the Effects of Once-Weekly Dulaglutide Injection and Once-Daily Glimepiride on Glucose Fluctuation of Type 2 Diabetes Mellitus Patients: A 26-Week Follow-Up.

    Li H · Journal of diabetes research · 2019

    Randomized controlled trial · 15 results

  45. Effects of Glucagon-Like Peptide-1 Receptor Agonists on Hypothalamic-Pituitary-Adrenal Axis in Healthy Volunteers.

    Winzeler B · The Journal of clinical endocrinology and metabolism · 2019

    Randomized controlled trial · 6 results

  46. Effects of GLP-1 Receptor Agonists on Bone Mineral Density in Patients with Type 2 Diabetes Mellitus: A 52-Week Clinical Study.

    Cai TT · BioMed research international · 2021

    Randomized controlled trial · 3 results

  47. Effect on Hemoglobin A1c (HbA1c) and Body Weight After Discontinuation of Tirzepatide, a Novel Glucose-Dependent Insulinotropic Peptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist: A Single-Center Case Series Study.

    Kubota M · Cureus · 2023

    Randomized controlled trial · 7 results

  48. A phase 1b randomised controlled trial of a glucagon-like peptide-1 and glucagon receptor dual agonist IBI362 (LY3305677) in Chinese patients with type 2 diabetes.

    Jiang H · Nature communications · 2022

    Randomized controlled trial · 13 results

  49. LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial.

    Urva S · Lancet (London, England) · 2022

    Randomized controlled trial · 13 results

  50. The dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist, tirzepatide, improves lipoprotein biomarkers associated with insulin resistance and cardiovascular risk in patients with type 2 diabetes.

    Wilson JM · Diabetes, obesity & metabolism · 2020

    Randomized controlled trial · 21 results

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