Link Between the Sensitivity of Kisspeptin Signalling and Pubertal Onset in Boys.
Ghulam Nabi30 participants26 Jun 2014 to 5 Mar 2015
Reproductive Physiological Phenomena
In PepBank now:147 peptides, 6 blends and 13 other compounds97,577 study results from 17,383 studies8,473 clinical trialsUpdated
Comparing 2 peptides · Data version 308560
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| Peptide | Synthetic analog Prostamax (KEDP) | Natural fragment Kisspeptin-10 | |
|---|---|---|---|
| Identity | |||
| Kind | Synthetic analog | Natural fragment | |
| Area | Sexual health and hormones | Sexual health and hormones | |
| Evidence | |||
| Amount of evidence | 9 | 1,457 (plus 233 on natural levels, listed separately) | |
| Evidence level | Results from lab studies only | Has results from studies in people | |
| Safety | |||
| Safety results | No safety results | 31 (0 in people) | |
| Status | |||
| Approval | Not recorded | ||
| Sport (WADA) | |||
| Registered trials | None registered | 17 · 3 active1 more mentions it but does not test it | |
Shared outcomes
From the regulatory data of each peptide.
Its most advanced trial is in phase 2. The FDA, the EMA and the other sources we use show no approval (as of 9 Oct 2026).
Outcome groups with study results for at least two of these peptides. Counts include only results from studies that gave the peptide. Bar length is the number of results, on one scale. The bars show how much was studied, not how large an effect was. A peptide with more studies can look stronger here without being stronger. For results, see the randomized results above.
| Outcome group | Prostamax (KEDP) | Kisspeptin-10 |
|---|---|---|
| Receptor activity and mechanismPharmacology | 66 | 242142189 |
PepBank is a research reference. Talk to a doctor before you use any peptide.
| Aging markersAging and longevity | 33 | 99 |
|---|
Each analog against its native parent, residue by residue. Substitutions, non-standard residues and modifications are marked. Calculated from the two sequences.
Kisspeptin-10 is the same as Kisspeptin-54 (metastin) residues 45 to 54, with 1 added group.
What is different
For each outcome that two or more peptides have results for: the best result of a single randomized trial, on the same measure (the same kind of number, the same unit). When a trial has several dose arms, the cell shows the highest dose arm. The trials differ in people, length and dose, so a gap between two cells is not proof that one peptide works better.
No outcome has a randomized-trial result on the same measure for two or more of these peptides yet.
Registered trials, ranked by phase (late phases first), then posted results and enrollment. Status is the registry status. Study results come from published studies. Results posted at ClinicalTrials.gov are shown on each trial page.
No registered trial that tests Prostamax (KEDP) found in ClinicalTrials.gov.
Top 3 of 17 trials, ranked by phase, then posted results and enrollment: 3 completed · source ClinicalTrials.gov (opens in a new tab)
Ghulam Nabi30 participants26 Jun 2014 to 5 Mar 2015
Reproductive Physiological Phenomena
Quaid-e-Azam University15 participants8 Aug 2014 to 5 Mar 2015
Sterility, Reproductive
Quaid-e-Azam University14 participants29 Oct 2013 to 10 Jan 2014
Kisspeptin Action on Insulin in Healthy Normal Men · Kisspeptin Action on Insulin in Obese Diabetic Men
1 more mentions it but does not test it. They only measure it or name it in their text.