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Trial · Interventional

CompletedNot applicableRegistry data

GnRH Agonist Administration in the Luteal Phase of ICSI-ET Cycles

NCTNCT00516490 (opens ClinicalTrials.gov in a new tab)Other idAH-47/07
Open at ClinicalTrials.govAsk about this trial

Overview

Status
Completed
Phase
Not applicable
Enrollment
570 participants (actual)
Sponsor
V.K.V. American Hospital, Istanbul · Other
Design
Randomized · Triple masking
Countries
1 country

Turkey (Türkiye)

Start
Sept 2006
Primary completion
Not stated
Completion
Jul 2007
First posted
15 Aug 2007 (estimated)
Last update posted
15 Aug 2007 (estimated)
Conditions
Infertility

Timeline

1 trial · 1 completed

  • Completed
  • Ongoing
  • Not yet recruiting
  • Stopped
  • Estimated dates (est.)
  • Results posted
200620072008
  1. N/A

    GnRH Agonist Administration in the Luteal Phase of ICSI-ET Cycles

    NCT00516490

    Sept 2006 to Jul 2007

Registry summary

Text and fields below are the sponsor's entries at ClinicalTrials.gov, shown as posted.

A single dose GnRH agonist administration in the luteal phase of assisted reproduction cycles was reported to increase pregnancy and birth rates. This study was done to evaluate the reproducibility of previous findings.

Interventions

  • triptorelin acetateDrug
  • Na Cl %0.9Drug

Arms2

  • Experimental

    1

    GnRH agonist administration

  • Placebo comparator

    2

    Sterile saline injection

Primary outcomes1

Outcomes the sponsor listed as primary.

  1. Ongoing pregnancy rate beyond 20 weeks

Secondary outcomes(2)

  1. Clinical pregnancy

  2. Embryo implantation rate

Posted results

Values are shown as posted at ClinicalTrials.gov, with their units. PepBank has not converted, pooled or compared them.

No results are posted for this trial.

Completed trials do not always post results.

Registry data comes from ClinicalTrials.gov. Study results come from studies, not from the registry. How PepBank works

Studies1

Studies that cite this trial.

Studies with results

1 study on this page

Indexing hint: Randomized controlled trial · 2006

6 results

Beneficial effect of luteal-phase GnRH agonist administration on embryo implantation after ICSI in both GnRH agonist- and antagonist-treated ovarian stimulation cycles.

Tesarik et al. 2006Human reproduction (Oxford, England)cited by 89

PMID 16926261DOI 10.1093/humrep/del173PUB-16926261

Full text at the publisher6 results
Publisher pageSee results (6)

Other registry references

References listed at the registry that are not in PepBank. They link to PubMed.

  • DerivedAta B, Yakin K, Balaban B, Urman B. GnRH agonist protocol administration in the luteal phase in ICSI-ET cycles stimulated with the long GnRH agonist protocol: a randomized, controlled double blind study. Hum Reprod. 2008 Mar;23(3):668-73. doi: 10.1093/humrep/dem421. Epub 2008 Jan 12. PMID 18192671

Eligibility

Who could join, as posted.

Sex
Female
Age
from 18 Years up to 45 Years
Healthy volunteers
Not accepted
Inclusion and exclusion criteria, as posted
Inclusion Criteria: * Women undergoing embryo transfer following controlled ovarian hyperstimulation with a long GnRH agonist protocol, oocyte pick-up and ICSI. * Embryo transfer performed on day 3. Exclusion Criteria: * Participation in another trial that was being conducted in our unit at the same time. * Preimplantation genetic screening cycles. * Day 5 embryo transfers.

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