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Study · Systematic review · 2026

2 resultsCorrected

Medical treatments for obesity: what does the future have in store?

Bassatne A, Rizo I

The Journal of clinical endocrinology and metabolism1 Oct 2026

CorrectedReported by Europe PMC

The publisher issued a correction. Read the notice to see what changed. PepBank shows the study as the source lists it today.

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanSystematic reviewEfficacy outcome

    In adults with obesity, a review of phase 2 and 3 trials reports that tirzepatide achieved weight reductions exceeding 20%.

    In plain wordsIn adults with obesity, a review reports that tirzepatide led to weight loss of more than 20%.

    Outcome
    DecreaseWeight reduction
    Study

    n: not reported in source

    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    Dose not stated

    Measurements

    weight reduction
    > 20%
    tirzepatide

    Source sentences

    Summary
    Tirzepatide, CagriSema, and amycretin achieved weight reductions exceeding 20%
    2 context sentences
    Summary · context
    A systematic literature search of the Medline database using MeSH terms and keywords related to new-generation obesity pharmacotherapy was conducted to identify articles published between 2021 and 2026.
    Summary · context
    Phase 2 and 3 clinical trials evaluating emerging obesity pharmacotherapies in adults and reporting outcomes, including weight loss and obesity-related complications, were included.
  2. 02HumanSystematic reviewEfficacy outcome

    In adults with obesity, a review of phase 2 and 3 trials reports that the triple agonist retatrutide produced weight reductions exceeding 25%.

    In plain wordsIn adults with obesity, a review reports that retatrutide led to weight loss of more than 25%.

    Outcome
    DecreaseWeight reduction
    Study

    n: not reported in source

    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    Dose not stated

    Measurements

    weight reduction
    > 25%
    retatrutide

    Source sentences

    Summary
    the triple agonist retatrutide produced reductions exceeding 25%.
    2 context sentences
    Summary · context
    A systematic literature search of the Medline database using MeSH terms and keywords related to new-generation obesity pharmacotherapy was conducted to identify articles published between 2021 and 2026.
    Summary · context
    Phase 2 and 3 clinical trials evaluating emerging obesity pharmacotherapies in adults and reporting outcomes, including weight loss and obesity-related complications, were included.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 37 to 40Current

    28 Oct 2026, 02:04 UTC

    The same notice was added 4 times, first on 27 Oct 2026, 18:19 UTC. The status did not change between them.

    Study results updated · status corrected

  2. Version 36

    27 Oct 2026, 16:32 UTC

    Study data updated · status corrected · source update from Europe PMC

  3. Versions 4 to 35

    22 Oct 2026, 02:26 UTC

    The same notice was added 32 times, first on 9 Oct 2026, 18:17 UTC. The status did not change between them.

    Study results updated

  4. Versions 2 to 3

    9 Oct 2026, 03:07 UTC

    The same notice was added 2 times, first on 9 Oct 2026, 03:04 UTC. The status did not change between them.

    Study data updated · source update from Europe PMC

  5. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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