In the systematic review of pediatric studies, semaglutide 2.4 mg/week had the greatest reported BMI reduction in adolescents with obesity.
In plain wordsIn reviewed adolescent obesity studies, semaglutide had the greatest reported BMI reduction.
- Peptide
- Semaglutide
- Outcome
- DecreaseBody mass index
- Study
n: not reported in source
- Outcome group
- Body weight · Metabolic and weight
- Studied dose
- 2.4 mg/weekAs given in this study (human).
Source sentences
Semaglutide 2.4 mg/week produced the greatest BMI reduction in adolescents with obesity, followed by liraglutide 3.0 mg/day, which also improved BMI SDS in adolescents and younger children.
2 context sentences(design, population, supporting numbers)
This review systematically evaluated the efficacy and safety of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in children and adolescents with obesity or T2DM.
PubMed-indexed studies published from 2000 to 2025 were reviewed, including seven pivotal randomized controlled trials and six meta-analyses involving 901 participants aged 6 to < 18 years.