In adults undergoing bariatric surgery, prior pooled GLP-1 receptor agonist treatment was associated with greater preoperative weight loss than no prior GLP-1 treatment (5.1 plus or minus 4.9% versus 2.4 plus or minus 3.7%; P=0.005).
In plain wordsBefore bariatric surgery, adults with pooled GLP-1 treatment had more weight loss than adults without prior GLP-1 treatment.
- Peptide
- Liraglutide
- Outcome
- IncreasePreoperative weight loss
- Study
n = 86
- Comparator
- No prior GLP-1 receptor agonist treatment
- Outcome group
- Body weight · Metabolic and weight
Measurements
- Preoperative weight loss
- 5.1%
- prior GLP-1 treatment; plus or minus 4.9
- Preoperative weight loss
- 2.4%
- no prior GLP-1 treatment; plus or minus 3.7; P=0.005
Source sentences
Patients treated with GLP1-RA achieved greater weight loss preoperatively (5.1% ± 4.9% vs. 2.4% ± 3.7%; p = 0.005) and at 1 month postoperatively (15.4% ± 5.2% vs. 13.0% ± 3.8%; p = 0.03), but not at 6 months.
3 context sentences(design, population, supporting numbers)
Retrospective observational study of adults who underwent BS at Clínica Universidad de Navarra (Madrid) between 2017 and 2023.
Overall, 86 patients (mean age, 46.6 ± 12 years; 66% women) were included; 80.2% and 19.8% underwent sleeve gastrectomy and gastric bypass, respectively.
Preoperative GLP1-RA therapy (63.4% liraglutide and 36.6% semaglutide) was prescribed in 34.8% of patients for a mean of 21.7 ± 15.9 weeks.
In this study, Liraglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Liraglutide.