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Study · Case report or series · n = 2 · 2021

3 results

Acute Kidney Injury Associated With Semaglutide.

Leehey DJ, Rahman MA, Borys E, Picken MM, Clise CE

Kidney medicine7 Jan 2021Cited by 43 (Europe PMC)

PMID33851124 (opens in a new tab)PMCIDPMC8039426 (opens in a new tab)DOI10.1016/j.xkme.2020.10.008 (opens in a new tab)PepBankPUB-33851124
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanCase report or seriesSafety outcome

    In 2 patients with diabetic chronic kidney disease, kidney function worsened rapidly after semaglutide was prescribed.

    In plain wordsTwo people with diabetic kidney disease had a rapid drop in kidney function after starting semaglutide.

    Peptide
    Semaglutide
    Outcome
    DecreaseWorsening of kidney function after semaglutide
    Study

    n = 2

    Outcome group
    Kidney function · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We report 2 patients with chronic kidney disease due to diabetic kidney disease who experienced rapid worsening of kidney function and increased proteinuria after being prescribed the GLP-1 receptor agonist semaglutide.
  2. 02HumanCase report or seriesSafety outcome

    In 2 patients with diabetic chronic kidney disease, proteinuria increased after semaglutide was prescribed.

    In plain wordsTwo people with diabetic kidney disease had more protein in the urine after starting semaglutide.

    Peptide
    Semaglutide
    Outcome
    IncreaseProteinuria after semaglutide
    Study

    n = 2

    Outcome group
    Kidney function · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We report 2 patients with chronic kidney disease due to diabetic kidney disease who experienced rapid worsening of kidney function and increased proteinuria after being prescribed the GLP-1 receptor agonist semaglutide.
  3. 03HumanCase report or seriesSafety outcome

    In 1 of the 2 patients, kidney biopsy showed advanced diffuse and nodular glomerulosclerosis, interstitial infiltrate and acute tubular injury.

    In plain wordsIn one of the two people, a kidney biopsy showed advanced scarring and signs of acute kidney tube injury.

    Peptide
    Semaglutide
    Outcome
    Not applicableKidney biopsy findings
    Study

    n = 1

    Outcome group
    Kidney function · Kidney and urinary
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We report 2 patients with chronic kidney disease due to diabetic kidney disease who experienced rapid worsening of kidney function and increased proteinuria after being prescribed the GLP-1 receptor agonist semaglutide.
    1 context sentence
    Summary · context
    In 1 patient, kidney biopsy showed advanced diffuse and nodular glomerulosclerosis accompanied by interstitial lymphoplasmacytic and eosinophilic infiltrate and evidence of acute tubular injury.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    12 Oct 2026, 11:11 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:06 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:05 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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