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Study · In vitro (cells) · paralichthys olivaceus (olive flounder) and paralichthys olivaceus · 2016

5 results

Native recombinant kisspeptin can induce gnrh1 and kissr2 expression in Paralichthys olivaceus in vitro.

Song H, Wang M, Qi J, Wang Z, Zhang Q

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology1 Jun 2016Cited by 6 (Europe PMC)

PMID27260091 (opens in a new tab)DOI10.1016/j.cbpb.2016.05.002 (opens in a new tab)PepBankPUB-27260091
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In cultured olive flounder brain cells, recombinant Kp10 induced expression of kissr2.

    In plain wordsIn cells from olive flounder brain, a kisspeptin‑10 protein raised activity of the kisspeptin receptor gene kissr2.

    Peptide
    Kisspeptin-10
    Outcome
    Increasekissr2 expression
    Study

    Paralichthys olivaceus (olive flounder)n: not reported in source

    Cultured brain cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In the dose course of treatments with prokaryotically expressed peptides, Kp54 and Kp10 could induce the expression of kissr2 and gnrh1
    1 context sentence
    Summary · context
    Kisspeptin fragments Kp54, Kp44, and Kp10 translated from Paralichthys olivaceus kiss2 gene were then obtained.
  2. 02LabIn vitro (cells)Mechanism

    In cultured olive flounder brain cells, recombinant Kp10 induced expression of gnrh1.

    In plain wordsIn cells from olive flounder brain, a kisspeptin‑10 protein raised activity of the gnrh1 gene.

    Peptide
    Kisspeptin-10
    Outcome
    Increasegnrh1 expression
    Study

    Paralichthys olivaceus (olive flounder)n: not reported in source

    Cultured brain cells
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In the dose course of treatments with prokaryotically expressed peptides, Kp54 and Kp10 could induce the expression of kissr2 and gnrh1
    1 context sentence
    Summary · context
    Kisspeptin fragments Kp54, Kp44, and Kp10 translated from Paralichthys olivaceus kiss2 gene were then obtained.
  3. 03LabIn vitro (cells)Activity measurement

    In cultured Paralichthys olivaceus brain cells, recombinant Kp54 induced kissr2 expression.

    In plain wordsIn cells from olive flounder brain, Kp54 raised kissr2 gene expression.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    Increasekissr2 expression
    Study

    Paralichthys olivaceusn: not reported in source

    cultured brain cells
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Kp54 and Kp10 could induce the expression of kissr2 and gnrh1
    1 context sentence
    Summary · context
    In our study, three kinds of recombinant kisspeptin proteins were expressed in Escherichia coli.
  4. 04LabIn vitro (cells)Activity measurement

    In cultured Paralichthys olivaceus brain cells, recombinant Kp54 induced gnrh1 expression.

    In plain wordsIn cells from olive flounder brain, Kp54 raised gnrh1 gene expression.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    Increasegnrh1 expression
    Study

    Paralichthys olivaceusn: not reported in source

    cultured brain cells
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Kp54 and Kp10 could induce the expression of kissr2 and gnrh1
    1 context sentence
    Summary · context
    In our study, three kinds of recombinant kisspeptin proteins were expressed in Escherichia coli.
  5. 05LabIn vitro (cells)Activity measurement

    In two kinds of cultured brain cells, Kp54 treatment gave different kissr2 and gnrh1 mRNA patterns over time, depending on cell type and treatment duration.

    In plain wordsIn two kinds of cultured flounder brain cells, the gene responses to Kp54 differed by cell type and treatment time.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    MixedTime course of kissr2 and gnrh1 mRNA
    Study

    Paralichthys olivaceusn: not reported in source

    cultured brain cells
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In the time course of the Kp54 treatments on two kinds of cultured brain cells, different patterns of kissr2 and gnrh1 mRNA suggested that the responses of these cells to kisspeptins depends on cell type and treatment duration.
    1 context sentence
    Summary · context
    In our study, three kinds of recombinant kisspeptin proteins were expressed in Escherichia coli.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 4 to 18Current

    28 Oct 2026, 02:02 UTC

    The same notice was added 15 times, first on 13 Oct 2026, 21:44 UTC. The status did not change between them.

    Study results updated

  2. Version 3

    13 Oct 2026, 16:31 UTC

    Study data updated · source update from Europe PMC

  3. Version 2

    10 Oct 2026, 09:43 UTC

    Study results updated

  4. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

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