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Study · Systematic review · 2015

1 result

Clinical review: Drugs commonly associated with weight change: a systematic review and meta-analysis.

Domecq JP, Prutsky G, Leppin A, Sonbol MB, Altayar O, Undavalli C, Wang Z, Elraiyah T, Brito JP, Mauck KF, Lababidi MH, Prokop LJ and 5 more

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Asi N, Wei J, Fidahussein S, Montori VM, Murad MH

The Journal of clinical endocrinology and metabolism15 Jan 2015Cited by 239 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanSystematic reviewEfficacy outcome

    In a meta-analysis of randomized trials, liraglutide use was associated with weight loss compared with placebo.

    In plain wordsIn a review of randomized trials, people taking liraglutide lost weight compared with people taking placebo.

    Outcome
    DecreaseWeight change versus placebo
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    Dose not stated

    Measurements

    Weight loss
    1.7 kg
    liraglutide vs placebo

    Source sentences

    Summary
    Weight loss was associated with the use of metformin (1.1 kg), acarbose (0.4 kg), miglitol (0.7 kg), pramlintide (2.3 kg), liraglutide (1.7 kg), exenatide (1.2 kg), zonisamide (7.7 kg), topiramate (3.8 kg), bupropion (1.3 kg), and fluoxetine (1.3 kg).
    1 context sentence
    Summary · context
    We included randomized trials that compared an a priori selected list of drugs to placebo and measured weight change.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 18:59 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    12 Oct 2026, 12:10 UTC

    Study results updated

  3. Version 1

    9 Oct 2026, 03:06 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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