In adults with type 2 diabetes, pooled GLP-1 receptor agonists (including semaglutide) did not change the risk of pancreatitis versus comparators.
In plain wordsIn adults with type 2 diabetes, GLP-1 drugs as a class, semaglutide among them, did not raise pancreatitis risk compared with comparators.
- Peptide
- Semaglutide
- Outcome
- No significant changePancreatitis risk
- Study
n = 14,972
- Comparator
- Placebo or active drugs
- Outcome group
- Adverse events · Gastrointestinal
Measurements
- MH-OR
- 1.01 ratio
- pancreatitis, GLP-1 RA vs comparators
Source sentences
The overall risk of pancreatitis was not different between GLP-1RA and comparators (MH-OR: 1.01[0.37; 2.76]; p = 0.99).
1 context sentence(design, population, supporting numbers)
(i) randomized trials, (ii) duration ≥12 weeks; (iii) on type 2 diabetes; and (iv) comparison of GLP-1RA with placebo or active drugs.
In this study, Semaglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Semaglutide.